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UniProtKB/Swiss-Prot entry Q9SU94


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name ANM11_ARATH
Primary accession number Q9SU94
Secondary accession numbers O81813 Q8VZP0
Integrated into Swiss-Prot on July 10, 2007
Sequence was last modified on May 1, 2000 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 45)
Name and origin of the protein
Protein name Probable protein arginine N-methyltransferase 1.1
Synonyms EC 2.1.1.-
Arginine methyltransferase pam1
Gene name
Name: PRMT1.1
Synonyms: PAM1
OrderedLocusNames: At4g29510
ORFNames: T16L4.20
From
Arabidopsis thaliana (Mouse-ear cress) [TaxID: 3702] 
Taxonomy Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliophyta; eudicotyledons; core eudicotyledons; rosids; eurosids II; Brassicales; Brassicaceae; Arabidopsis.
Protein existence 1: Evidence at protein level;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=cv. Columbia;
DOI=10.1038/47134; PubMed=10617198 [NCBI, ExPASy, EBI, Israel, Japan]
Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T., Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B., Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M., de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M., Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D., Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J., Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B., Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J., Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R., Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M., Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P., Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S., Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C., Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J., Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S., Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A., Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M., Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D., Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E., Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S., Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R., Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M., Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E., Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P., Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K., Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K., de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K., Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M., Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G., Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K., Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K., Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W., Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H., Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B., Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J., Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K., O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N., Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A., Martienssen R., McCombie W.R.;
"Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
Nature 402:769-777(1999).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
STRAIN=cv. Columbia;
DOI=10.1126/science.1088305; PubMed=14593172 [NCBI, ExPASy, EBI, Israel, Japan]
Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.;
"Empirical analysis of transcriptional activity in the Arabidopsis genome.";
Science 302:842-846(2003).
[3]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B., Feldmann K.A.;
"Full-length cDNA from Arabidopsis thaliana.";
Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
[4]
NUCLEOTIDE SEQUENCE [MRNA] OF 1-376.
STRAIN=cv. Columbia;
Salchert K., Breuer F., Koncz C.;
"Identification and isolation of the first protein arginine methyltransferase from Arabidopsis thaliana.";
Submitted (JUL-1998) to the EMBL/GenBank/DDBJ databases.
[5]
GENE FAMILY, AND NOMENCLATURE.
DOI=10.1016/j.pharmthera.2006.06.007; PubMed=17005254 [NCBI, ExPASy, EBI, Israel, Japan]
Krause C.D., Yang Z.H., Kim Y.S., Lee J.H., Cook J.R., Pestka S.;
"Protein arginine methyltransferases: evolution and assessment of their pharmacological and therapeutic potential.";
Pharmacol. Ther. 113:50-87(2007).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AL079344; CAB45311.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AL161575; CAB79709.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AY150407; AAN12952.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AY063970; AAL36326.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AY087817; AAM65371.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AJ007582; CAA07570.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR T09914; T09914.
T52248; T52248.
RefSeq NP_194680.1; -.
UniGene At.27463
3D structure databases
HSSP Q63009; 1ORH. [HSSP ENTRY / PDB]
ModBase Q9SU94.
Protein-protein interaction databases
IntAct Q9SU94; -.
Organism-specific databases
TAIR At4g29510; -.
Ontologies
GO
GO:0005634; Cellular component: nucleus (inferred from direct assay from TAIR).
GO:0042802; Molecular function: identical protein binding (inferred from physical interaction from IntAct).
GO:0016274; Molecular function: protein-arginine N-methyltransferase activity (inferred from direct assay from TAIR).
QuickGo view.
Family and domain databases
InterPro IPR013217; Methyltransf_12.
Graphical view of domain structure.
Pfam PF08242; Methyltransf_12; 1.
Pfam graphical view of domain structure.
BLOCKS Q9SU94.
Genome annotation databases
GeneID 829072; -.
GenomeReviews CT486007_GR; AT4G29510.
KEGG ath:AT4G29510; -.
NMPDR fig|3702.1.peg.20921; -.
Other
ProtoNet Q9SU94.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Methyltransferase; Nucleus; Transferase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   390  390     Probable protein arginine N-methyltransferase 1.1. PRO_0000293986
CONFLICT   260   260        D -> G (in Ref. 2; AAL36326). 
Sequence information
Length: 390 AA [This is the length of the unprocessed precursor] Molecular weight: 43894 Da [This is the MW of the unprocessed precursor] CRC64: 9BE43387CD7AE0B2 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MTKNSNHDEN EFISFEPNQN TKIRFEDADE DEVAEGSGVA GEETPQDESM FDAGESADTA 

        70         80         90        100        110        120 
EVTDDTTSAD YYFDSYSHFG IHEEMLKDVV RTKTYQNVIY QNKFLIKDKI VLDVGAGTGI 

       130        140        150        160        170        180 
LSLFCAKAGA AHVYAVECSQ MADMAKEIVK ANGFSDVITV LKGKIEEIEL PTPKVDVIIS 

       190        200        210        220        230        240 
EWMGYFLLFE NMLDSVLYAR DKWLVEGGVV LPDKASLHLT AIEDSEYKED KIEFWNSVYG 

       250        260        270        280        290        300 
FDMSCIKKKA MMEPLVDTVD QNQIVTDSRL LKTMDISKMS SGDASFTAPF KLVAQRNDYI 

       310        320        330        340        350        360 
HALVAYFDVS FTMCHKLLGF STGPKSRATH WKQTVLYLED VLTICEGETI TGTMSVSPNK 

       370        380        390 
KNPRDIDIKL SYSLNGQHCK ISRTQHYKMR 

Q9SU94 in FASTA format

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