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UniProtKB/Swiss-Prot entry Q9K9W1

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name PYRD_BACHD
Primary accession number Q9K9W1
Secondary accession numbers None
Integrated into Swiss-Prot on January 23, 2002
Sequence was last modified on October 1, 2000 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 57)
Name and origin of the protein
Protein name Dihydroorotate dehydrogenase
Synonyms EC 1.3.3.1
Dihydroorotate oxidase
DHOdehase
DHODase
DHOD
Gene name
Name: pyrD
OrderedLocusNames: BH2534
From
Bacillus halodurans [TaxID: 86665] [HAMAP proteome]
Taxonomy Bacteria; Firmicutes; Bacillales; Bacillaceae; Bacillus.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC BAA-125 / C-125 / DSM 18197 / FERM 7344 / JCM 9153;
DOI=10.1093/nar/28.21.4317; PubMed=11058132 [NCBI, ExPASy, EBI, Israel, Japan]
Takami H., Nakasone K., Takaki Y., Maeno G., Sasaki R., Masui N., Fuji F., Hirama C., Nakamura Y., Ogasawara N., Kuhara S., Horikoshi K.;
"Complete genome sequence of the alkaliphilic bacterium Bacillus halodurans and genomic sequence comparison with Bacillus subtilis.";
Nucleic Acids Res. 28:4317-4331(2000).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
BA000004; BAB06253.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR F83966; F83966.
RefSeq NP_243400.1; -.
3D structure databases
HSSP P54322; 1EP2. [HSSP ENTRY / PDB]
ModBase Q9K9W1.
Enzyme and pathway databases
BioCyc BHAL272558:BH2534-MON; -.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0004158; Molecular function: dihydroorotate oxidase activity (inferred from electronic annotation from HAMAP).
GO:0006207; Biological process: 'de novo' pyrimidine base biosynthetic process (inferred from electronic annotation from InterPro).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
GO:0006222; Biological process: UMP biosynthetic process (inferred from electronic annotation from InterPro).
QuickGo view.
Family and domain databases
HAMAP MF_00224; -; 1.
PBIL [Tree]
InterPro IPR013785; Aldolase_TIM.
IPR012135; DHO_DHase_1_2.
IPR005720; DHO_DHase_1_core.
IPR001295; Dihydroorotate_DHase_core.
Graphical view of domain structure.
Gene3D G3DSA:3.20.20.70; Aldolase_TIM; 1.
Pfam PF01180; DHO_dh; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000164; DHO_oxidase; 1.
TIGRFAMs TIGR01037; pyrD_sub1_fam; 1.
PROSITE PS00911; DHODEHASE_1; 1.
PS00912; DHODEHASE_2; 1.
BLOCKS Q9K9W1.
ProtoNet Q9K9W1.
Genome annotation databases
GeneID 891493; -.
GenomeReviews BA000004_GR; BH2534.
KEGG bha:BH2534; -.
NMPDR fig|272558.1.peg.2534; -.
Phylogenomic databases
HOGENOM Q9K9W1; -.
Genome annotation databases
CMR Q9K9W1; BH2534.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Cytoplasm; Flavoprotein; FMN; Oxidoreductase; Pyrimidine biosynthesis.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   305  305     Dihydroorotate dehydrogenase. PRO_0000148388
ACT_SITE   130   130        Nucleophile (By similarity). 
Sequence information
Length: 305 AA [This is the length of the unprocessed precursor] Molecular weight: 32133 Da [This is the MW of the unprocessed precursor] CRC64: 726B468AA5ECD726 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MSRLAVELPG LSMKNPIMPA SGCFGFGKEF AGFYDLNHLG AIAIKATTVE PRFGNPTPRV 

        70         80         90        100        110        120 
AETHSGMLNA IGLQNPGLNN VIDNELARLA DVDVPIVANI AGSTVNDYVE VAEAISRVDN 

       130        140        150        160        170        180 
VHALELNISC PNVKEGGIAF GTVPDVAAQL TQEVKRVSTV PVYVKLSPNV SDIVEMAQAV 

       190        200        210        220        230        240 
ERAGADGLSM INTLLGMRLD LKRRTPILAN GTGGLSGPAI KPVAIRMIYQ VSQAVSIPII 

       250        260        270        280        290        300 
GMGGIQSADD VLEFMLAGAD AVAVGTANFT DPYVCPTIID ELPKRMDELG IERIADIVGG 


SWKQS
Q9K9W1 in FASTA format

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