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UniProtKB/Swiss-Prot entry Q9JXX4

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name CARA_NEIMB
Primary accession number Q9JXX4
Secondary accession numbers None
Integrated into Swiss-Prot on July 11, 2002
Sequence was last modified on October 1, 2000 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 58)
Name and origin of the protein
Protein name Carbamoyl-phosphate synthase small chain
Synonyms EC 6.3.5.5
Carbamoyl-phosphate synthetase glutamine chain
Gene name
Name: carA
OrderedLocusNames: NMB1849
From
Neisseria meningitidis serogroup B [TaxID: 491] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Betaproteobacteria; Neisseriales; Neisseriaceae; Neisseria.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=MC58 / Serogroup B;
DOI=10.1126/science.287.5459.1809; PubMed=10710307 [NCBI, ExPASy, EBI, Israel, Japan]
Tettelin H., Saunders N.J., Heidelberg J.F., Jeffries A.C., Nelson K.E., Eisen J.A., Ketchum K.A., Hood D.W., Peden J.F., Dodson R.J., Nelson W.C., Gwinn M.L., DeBoy R.T., Peterson J.D., Hickey E.K., Haft D.H., Salzberg S.L., White O., Fleischmann R.D., Dougherty B.A., Mason T.M., Ciecko A., Parksey D.S., Blair E., Cittone H., Clark E.B., Cotton M.D., Utterback T.R., Khouri H.M., Qin H., Vamathevan J.J., Gill J., Scarlato V., Masignani V., Pizza M., Grandi G., Sun L., Smith H.O., Fraser C.M., Moxon E.R., Rappuoli R., Venter J.C.;
"Complete genome sequence of Neisseria meningitidis serogroup B strain MC58.";
Science 287:1809-1815(2000).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE002098; AAF42183.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR F81034; F81034.
RefSeq NP_274845.1; -.
3D structure databases
HSSP P00907; 1M6V. [HSSP ENTRY / PDB]
ModBase Q9JXX4.
Enzyme and pathway databases
BioCyc NMEN122586:NMB_1849-MON; -.
Ontologies
GO
GO:0005524; Molecular function: ATP binding (inferred from electronic annotation from HAMAP).
GO:0004088; Molecular function: carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity (inferred from electronic annotation from HAMAP).
GO:0006526; Biological process: arginine biosynthetic process (inferred from electronic annotation from HAMAP).
GO:0006541; Biological process: glutamine metabolic process (inferred from electronic annotation from InterPro).
GO:0006221; Biological process: pyrimidine nucleotide biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_01209; -; 1.
PBIL [Tree]
InterPro IPR006220; Anth_synthII.
IPR001317; CarbamoylP_synth_GATase.
IPR006274; CarbamoylP_synth_ssu.
IPR002474; CarbamoylP_synth_ssu_N.
IPR011702; GATASE.
IPR012998; GATase_1_AS.
IPR000991; GATase_class1_C.
Graphical view of domain structure.
PANTHER PTHR11405:SF4; CarA_synth_small; 1.
Pfam PF00988; CPSase_sm_chain; 1.
PF00117; GATase; 1.
Pfam graphical view of domain structure.
PRINTS PR00097; ANTSNTHASEII.
PR00099; CPSGATASE.
PR00096; GATASE.
TIGRFAMs TIGR01368; CPSaseIIsmall; 1.
PROSITE PS51273; GATASE_TYPE_1; 1.
PROSITE graphical view of domain structure (profiles).
BLOCKS Q9JXX4.
ProtoNet Q9JXX4.
Genome annotation databases
GeneID 903249; -.
GenomeReviews AE002098_GR; NMB1849.
KEGG nme:NMB1849; -.
NMPDR fig|122586.1.peg.1779; -.
TIGR NMB1849; -.
Phylogenomic databases
HOGENOM Q9JXX4; -.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Amino-acid biosynthesis; Arginine biosynthesis; Complete proteome; Glutamine amidotransferase; Ligase; Pyrimidine biosynthesis.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   377  377     Carbamoyl-phosphate synthase small chain. PRO_0000112299
DOMAIN   190   377  188     Glutamine amidotransferase type-1. 
REGION   1   186  186     CPSase. 
ACT_SITE   266   266        Nucleophile (By similarity). 
ACT_SITE   350   350        By similarity. 
ACT_SITE   352   352        By similarity. 
Sequence information
Length: 377 AA [This is the length of the unprocessed precursor] Molecular weight: 40587 Da [This is the MW of the unprocessed precursor] CRC64: 36733FC0806B1670 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MSTPALLVLA DGSVFHGTSI GYEGSTSGEV VFNTSMTGYQ EILTDPSYCK QIVTLTYPHI 

        70         80         90        100        110        120 
GNTGTNAEDE ESRSVYAAGL IIRDLPLLHS NFRASESLHD YLVRNKTVAI ADIDTRRLTT 

       130        140        150        160        170        180 
LLREKGAQGG AILTGADATI EKAQELIAAF GSMVGKDLAK EVSCTETYEW TEGEWALGKG 

       190        200        210        220        230        240 
FVTPDEQPYH VVAYDFGVKT NILRMLASRG CRLTVVPAQT SAEDVLALNP DGVFLSNGPG 

       250        260        270        280        290        300 
DPEPCTYAIK AVQKLIESGK PIFGICLGHQ LISLAIGAKT LKMRFSHHGA NHPVQDLDSG 

       310        320        330        340        350        360 
KVVITSQNHG FAVDADTLPA NARITHKSLF DNTLQGIELT DKPVFCFQGH PEASPGPQDV 

       370 
GYLFDKFIGN MKAAKRA
Q9JXX4 in FASTA format

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