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UniProtKB/Swiss-Prot entry Q9J584


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name MCEL_FOWPV
Primary accession number Q9J584
Secondary accession numbers None
Integrated into Swiss-Prot on August 29, 2001
Sequence was last modified on October 1, 2000 (Sequence version 1)
Annotations were last modified on    November 4, 2008 (Entry version 30)
Name and origin of the protein
Protein name mRNA-capping enzyme large subunit
Synonyms None
Includes Polynucleotide 5'-triphosphatase
     (EC 3.1.3.33)
     (mRNA 5'-triphosphatase)
     (TPase)
mRNA guanylyltransferase
     (EC 2.7.7.50)
     (GTP--RNA guanylyltransferase)
     (GTase)
Gene name
OrderedLocusNames: FPV146
From
Fowlpox virus (FPV) [TaxID: 10261] 
Taxonomy Viruses; dsDNA viruses, no RNA stage; Poxviridae; Chordopoxvirinae; Avipoxvirus.
Virus host Vertebrata [TaxID: 7742]
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1128/JVI.74.8.3815-3831.2000; PubMed=10729156 [NCBI, ExPASy, EBI, Israel, Japan]
Afonso C.L., Tulman E.R., Lu Z., Zsak L., Kutish G.F., Rock D.L.;
"The genome of fowlpox virus.";
J. Virol. 74:3815-3831(2000).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AF198100; AAF44490.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_039109.1; -.
3D structure databases
ModBase Q9J584.
Ontologies
GO
GO:0004484; Molecular function: mRNA guanylyltransferase activity (inferred from electronic annotation from EC).
GO:0004651; Molecular function: polynucleotide 5'-phosphatase activity (inferred from electronic annotation from EC).
QuickGo view.
Family and domain databases
InterPro IPR004971; Pox_MCEL.
Graphical view of domain structure.
Pfam PF03291; Pox_MCEL; 1.
Pfam graphical view of domain structure.
BLOCKS Q9J584.
ProtoNet Q9J584.
Genome annotation databases
GeneID 1486694; -.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Hydrolase; mRNA capping; mRNA processing; Multifunctional enzyme; Nucleotidyltransferase; Transferase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   851  851     mRNA-capping enzyme large subunit. PRO_0000210130
ACT_SITE   266   266        N6-GMP-lysine intermediate (Potential). 
Sequence information
Length: 851 AA [This is the length of the unprocessed precursor] Molecular weight: 98888 Da [This is the MW of the unprocessed precursor] CRC64: DC3607ADD634BA7A [This is a checksum on the sequence]
        10         20         30         40         50         60 
MDKYISKTPL SCYFEELVDT FISVVNSINK VDESKHHEVE LILFKPPIIT LTNLYNMATT 

        70         80         90        100        110        120 
TESYIEFTML PVDKPNTKFR NRIPLSKIHG LDVKNNQLVE SLDGFIWEEK SLLLKKDISD 

       130        140        150        160        170        180 
NSSAIIKYSI EEKTLFVDYK RRNASIKLEL VSVVRAKLRN IVIDFKMKYF LGSGAQSANS 

       190        200        210        220        230        240 
SSLLCALNHP KNKPSLYIEF EIMMQDKNIS KKKLLEELNM SASALFLSHP KYIRLCPSIN 

       250        260        270        280        290        300 
PILRTHLLKK QDIININTDD LYITSKTDGI FSHVYIEKKS IFCYFSHLGY IKEYTASREI 

       310        320        330        340        350        360 
EETIYLYAEM RKEESILYLT VIKVLKPCME DRLSELAFVK NHLTGIHDRL VFVTKCYDGP 

       370        380        390        400        410        420 
FESSSDLVVS IEEMLKTEQE GIILFYSKGE DSTTDYKVKK DNTIDQCVNV IYRYMSSEPI 

       430        440        450        460        470        480 
VFNDKGSFLE YKRYSNDKGF PKEFSTGKLD LNGSVEYINN IYCIEIKHLN PCTGITNLVL 

       490        500        510        520        530        540 
PIKFIAEFSH NDELIQPRID KTMKYLYESG YYGNQLSVIM DHLNDQKLRI GDVFEEEKLA 

       550        560        570        580        590        600 
DIAAHMKLKD SMRLNPDGNY FLSNRVRGAL GILSNFVKTL LISLYCSKTY LDNHSKRKVL 

       610        620        630        640        650        660 
AIDFGNGADL EKYFYGEIAL MVATDPDDNA IETGKKRYNE RNAGDKSKYY KFNYIKETIR 

       670        680        690        700        710        720 
SETYVSSIRQ VLYFEKFSLV DWQFAIHYSF HPKHYSTIMT NLQELTESGC KVLITTMDGD 

       730        740        750        760        770        780 
YLDTLKEKKK FIIRKLLPET ENYLSIEKID DDKVLVYNPS SMSKPMAEYI VRRDTLIRVF 

       790        800        810        820        830        840 
REYKFKLIDS CNFKTIIDRN ISFINGVSRL ESRGSTKNFF ELNRKALEEC NDTDVLELLS 

       850 
HYMVYVFSKE V 

Q9J584 in FASTA format

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