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UniProtKB/Swiss-Prot entry Q99TZ0

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name P5CR_STAAM
Primary accession number Q99TZ0
Secondary accession numbers None
Integrated into Swiss-Prot on December 20, 2005
Sequence was last modified on June 1, 2001 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 38)
Name and origin of the protein
Protein name Pyrroline-5-carboxylate reductase
Synonyms P5C reductase
P5CR
EC 1.5.1.2
Gene name
Name: proC
OrderedLocusNames: SAV1503
From
Staphylococcus aureus (strain Mu50 / ATCC 700699) [TaxID: 158878] [HAMAP proteome]
Taxonomy Bacteria; Firmicutes; Bacillales; Staphylococcus.
Protein existence 1: Evidence at protein level;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1016/S0140-6736(00)04403-2; PubMed=11418146 [NCBI, ExPASy, EBI, Israel, Japan]
Kuroda M., Ohta T., Uchiyama I., Baba T., Yuzawa H., Kobayashi I., Cui L., Oguchi A., Aoki K., Nagai Y., Lian J.-Q., Ito T., Kanamori M., Matsumaru H., Maruyama A., Murakami H., Hosoyama A., Mizutani-Ui Y., Takahashi N.K., Sawano T., Inoue R., Kaito C., Sekimizu K., Hirakawa H., Kuhara S., Goto S., Yabuzaki J., Kanehisa M., Yamashita A., Oshima K., Furuya K., Yoshino C., Shiba T., Hattori M., Ogasawara N., Hayashi H., Hiramatsu K.;
"Whole genome sequencing of meticillin-resistant Staphylococcus aureus.";
Lancet 357:1225-1240(2001).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
BA000017; BAB57665.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_372027.1; -.
3D structure databases
ModBase Q99TZ0.
Enzyme and pathway databases
BioCyc SAUR158878:SAV1503-MON; -.
2D gel databases
World-2DPAGE 0002:Q99TZ0; -.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from UniProtKB-KW).
GO:0005488; Molecular function: binding (inferred from electronic annotation from InterPro).
GO:0004735; Molecular function: pyrroline-5-carboxylate reductase activity (inferred from electronic annotation from InterPro).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
GO:0006561; Biological process: proline biosynthetic process (inferred from electronic annotation from InterPro).
QuickGo view.
Family and domain databases
InterPro IPR004455; NADP_OxRdtase_F420.
IPR000304; P5CR.
Graphical view of domain structure.
PANTHER PTHR11645; P5CR; 1.
Pfam PF03807; F420_oxidored; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000193; Pyrrol-5-carb_rd; 1.
TIGRFAMs TIGR00112; proC; 1.
Genome annotation databases
GeneID 1121478; -.
GenomeReviews BA000017_GR; SAV1503.
KEGG sav:SAV1503; -.
Phylogenomic databases
HOGENOM Q99TZ0; -.
Other
LinkHub Q99TZ0; -.
Genome annotation databases
CMR Q99TZ0; SAV1503.
Other
ProtoNet Q99TZ0.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Amino-acid biosynthesis; Complete proteome; Cytoplasm; NADP; Oxidoreductase; Proline biosynthesis.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   271  271     Pyrroline-5-carboxylate reductase. PRO_0000187299
Sequence information
Length: 271 AA [This is the length of the unprocessed precursor] Molecular weight: 29826 Da [This is the MW of the unprocessed precursor] CRC64: BBFB9C15896A9633 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MKLVFYGAGN MAQAIFTGII NSSNLDANDI YLTNKSNEQA LKAFAEKLGV NYSYDDATLL 

        70         80         90        100        110        120 
KDADYVFLGT KPHDFDALAT RIKPHITKDN CFISIMAGIP IDYIKQQLEC QNPVARIMPN 

       130        140        150        160        170        180 
TNAQVGHSVT GISFSNNFDP KSKDEINDLV KAFGSVIEVS EDHLHQVTAI TGSGPAFLYH 

       190        200        210        220        230        240 
VFEQYVKAGT KLGLEKEQVE ESIRNLIIGT SKMIERSDLS MAQLRKNITS KGGTTQAGLD 

       250        260        270 
TLSQYDLVSI FEDCLNAAVD RSIELSNVED Q
Q99TZ0 in FASTA format

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