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UniProtKB/Swiss-Prot entry Q92IR2


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name UCRI_RICCN
Primary accession number Q92IR2
Secondary accession numbers None
Integrated into Swiss-Prot on May 15, 2007
Sequence was last modified on December 1, 2001 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 39)
Name and origin of the protein
Protein name Ubiquinol-cytochrome c reductase iron-sulfur subunit
Synonyms EC 1.10.2.2
Rieske iron-sulfur protein
RISP
Gene name
Name: petA
OrderedLocusNames: RC0358
From
Rickettsia conorii [TaxID: 781] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales; Rickettsiaceae; Rickettsieae; Rickettsia; spotted fever group.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC VR-613 / Malish 7;
DOI=10.1126/science.1061471; PubMed=11557893 [NCBI, ExPASy, EBI, Israel, Japan]
Ogata H., Audic S., Renesto-Audiffren P., Fournier P.-E., Barbe V., Samson D., Roux V., Cossart P., Weissenbach J., Claverie J.-M., Raoult D.;
"Mechanisms of evolution in Rickettsia conorii and R. prowazekii.";
Science 293:2093-2098(2001).
Comments
  • FUNCTION: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
  • CATALYTIC ACTIVITY: QH2 + 2 ferricytochrome c = Q + 2 ferrocytochrome c + 2 H+.
  • COFACTOR: Binds 1 2Fe-2S cluster per subunit (By similarity).
  • SUBUNIT: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.
  • SUBCELLULAR LOCATION: Cell membrane; Single-pass membrane protein (Potential).
  • MISCELLANEOUS: The Rieske protein is a high potential 2Fe-2S protein.
  • SIMILARITY: Contains 1 Rieske domain.
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE008601; AAL02896.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR F97744; F97744.
RefSeq NP_359995.1; -.
3D structure databases
HSSP P13272; 1RIE. [HSSP ENTRY / PDB]
ModBase Q92IR2.
Enzyme and pathway databases
BioCyc RCON272944:RC0358-MON; -.
Ontologies
GO
GO:0016021; Cellular component: integral to membrane (inferred from electronic annotation from UniProtKB-KW).
GO:0005886; Cellular component: plasma membrane (inferred from electronic annotation from UniProtKB-KW).
GO:0051537; Molecular function: 2 iron, 2 sulfur cluster binding (inferred from electronic annotation from InterPro).
GO:0009055; Molecular function: electron carrier activity (inferred from electronic annotation from InterPro).
GO:0005506; Molecular function: iron ion binding (inferred from electronic annotation from UniProtKB-KW).
GO:0008121; Molecular function: ubiquinol-cytochrome-c reductase activity (inferred from electronic annotation from InterPro).
GO:0022900; Biological process: electron transport chain (inferred from electronic annotation from UniProtKB-KW).
GO:0006810; Biological process: transport (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
InterPro IPR014349; Rieske.
IPR005805; Rieske_C.
IPR006317; Rieske_proteo.
IPR005806; Rieske_reg.
IPR006311; Tat.
Graphical view of domain structure.
Gene3D G3DSA:2.102.10.10; Rieske_reg; 1.
PANTHER PTHR10134; Rieske; 1.
Pfam PF00355; Rieske; 1.
Pfam graphical view of domain structure.
PRINTS PR00162; RIESKE.
TIGRFAMs TIGR01416; Rieske_proteo; 1.
TIGR01409; TAT_signal_seq; 1.
PROSITE PS51296; RIESKE; 1.
PS51318; TAT; 1.
PROSITE graphical view of domain structure (profiles).
ProtoNet Q92IR2.
Genome annotation databases
GeneID 927519; -.
GenomeReviews AE006914_GR; RC0358.
KEGG rco:RC0358; -.
NMPDR fig|272944.1.peg.358; -.
Phylogenomic databases
HOGENOM Q92IR2; -.
Genome annotation databases
CMR Q92IR2; RC0358.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
2Fe-2S; Cell membrane; Complete proteome; Electron transport; Iron; Iron-sulfur; Membrane; Metal-binding; Oxidoreductase; Transmembrane; Transport.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   177  177     Ubiquinol-cytochrome c reductase iron-sulfur subunit. PRO_0000286642
TRANSMEM   18    38  21     Potential. 
DOMAIN   88   175  88     Rieske. 
METAL   120   120        Iron-sulfur (2Fe-2S) (By similarity). 
METAL   122   122        Iron-sulfur (2Fe-2S); via pros nitrogen (By similarity). 
METAL   139   139        Iron-sulfur (2Fe-2S) (By similarity). 
METAL   142   142        Iron-sulfur (2Fe-2S); via pros nitrogen (By similarity). 
DISULFID   125   141        By similarity. 
Sequence information
Length: 177 AA [This is the length of the unprocessed precursor] Molecular weight: 19211 Da [This is the MW of the unprocessed precursor] CRC64: C40EAD3C4D1ABD40 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MSDTEDNKNK QTTRRDFMVL TASSVAAIGA VCTLWPLVDS LNPSADVLAL SSIEVDLSNI 

        70         80         90        100        110        120 
AVGQTVTVKW QGKPVFITNR TPDKIAEARA VKMSELIDPE ADQARVKAGH DNWLVTIGIC 

       130        140        150        160        170 
THLGCVPLAN QGEYDGWFCP CHGSQYDSSG RVRRGPAPLN LAVPPYTFIS DKKIRIG 

Q92IR2 in FASTA format

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