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UniProtKB/Swiss-Prot entry Q8Z553

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information

Entry name

GLPB_SALTI

Primary accession number

Q8Z553

Secondary accession numbers

None

Integrated into Swiss-Prot on

March 29, 2004

Sequence was last modified on

March 1, 2002 (Sequence version 1)

Annotations were last modified on

November 25, 2008 (Entry version 44)

Name and origin of the protein

Protein name

Anaerobic glycerol-3-phosphate dehydrogenase subunit B

Synonyms

Anaerobic G-3-P dehydrogenase subunit B
Anaerobic G3Pdhase B
EC 1.1.99.5

Gene name

	Name:	glpB
	OrderedLocusNames:	STY2514, t0579

From

Salmonella typhi

[TaxID: 601]

[HAMAP proteome]

Taxonomy

Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Salmonella.

Protein existence

3: Inferred from homology;

References

[1]

NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=CT18;
DOI=10.1038/35101607; PubMed=11677608 [NCBI, ExPASy, EBI, Israel, Japan]
Parkhill J., Dougan G., James K.D., Thomson N.R., Pickard D., Wain J., Churcher C.M., Mungall K.L., Bentley S.D., Holden M.T.G., Sebaihia M., Baker S., Basham D., Brooks K., Chillingworth T., Connerton P., Cronin A., Davis P., Davies R.M., Dowd L., White N., Farrar J., Feltwell T., Hamlin N., Haque A., Hien T.T., Holroyd S., Jagels K., Krogh A., Larsen T.S., Leather S., Moule S., O'Gaora P., Parry C., Quail M.A., Rutherford K.M., Simmonds M., Skelton J., Stevens K., Whitehead S., Barrell B.G.;
"Complete genome sequence of a multiple drug resistant Salmonella enterica serovar Typhi CT18.";
Nature 413:848-852(2001).

[2]

NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 700931 / Ty2;
DOI=10.1128/JB.185.7.2330-2337.2003; PubMed=12644504 [NCBI, ExPASy, EBI, Israel, Japan]
Deng W., Liou S.-R., Plunkett G. III, Mayhew G.F., Rose D.J., Burland V., Kodoyianni V., Schwartz D.C., Blattner F.R.;
"Comparative genomics of Salmonella enterica serovar Typhi strains Ty2 and CT18.";
J. Bacteriol. 185:2330-2337(2003).

Comments

FUNCTION: Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor (By similarity).
CATALYTIC ACTIVITY: sn-glycerol 3-phosphate + acceptor = glycerone phosphate + reduced acceptor.
COFACTOR: FMN (By similarity).
PATHWAY: Polyol metabolism; glycerol degradation via glycerol kinase pathway; glycerone phosphate from sn-glycerol 3-phosphate (anaerobic route): step 1/1 .
SUBUNIT: Composed of a catalytic glpA/B dimer and of membrane bound glpC (By similarity).
SUBCELLULAR LOCATION: Cell inner membrane; Peripheral membrane protein (By similarity). Note=Loosely bound to the cytoplasmic membrane often occurring in vesicles associated with fumarate reductase (By similarity).
SIMILARITY: Belongs to the anaerobic G-3-P dehydrogenase subunit B family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

AL627274; CAD07517.1; -; Genomic_DNA.	[EMBL / GenBank / DDBJ] [CoDingSequence]
AE014613; AAO68285.1; -; Genomic_DNA.	[EMBL / GenBank / DDBJ] [CoDingSequence]

RefSeq

NP_456828.1; -.
NP_804436.1; -.

3D structure databases

ModBase

Q8Z553.

Enzyme and pathway databases

BioCyc

SENT209261:T0579-MON; -.
SENT220341:STY2514-MON; -.

Ontologies

GO:0005886;	Cellular component: plasma membrane (inferred from electronic annotation from UniProtKB-KW).
GO:0009055;	Molecular function: electron carrier activity (inferred from electronic annotation from InterPro).
GO:0004368;	Molecular function: glycerol-3-phosphate dehydrogenase activity (inferred from electronic annotation from HAMAP).
GO:0055114;	Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.

Family and domain databases

HAMAP

MF_00753; -; 1.
PBIL [Tree]

InterPro

IPR009158; Anaerobic_glycerol3P_DH_bsu.
IPR003953; FAD_bind2_N.
IPR013027; FAD_pyr_nucl-diS_OxRdtase.
Graphical view of domain structure.

Pfam

PF00890; FAD_binding_2; 1.
Pfam graphical view of domain structure.

PIRSF

PIRSF000141; Anaerobic_G3P_dh; 1.

PRINTS

PR00368; FADPNR.

TIGRFAMs

TIGR03378; glycerol3P_GlpB; 1.

ProtoNet

Q8Z553.

Genome annotation databases

GeneID

1069605; -.
1248840; -.

GenomeReviews

AL513382_GR; STY2514.
AE014613_GR; t0579.

KEGG

stt:t0579; -.
sty:STY2514; -.

Phylogenomic databases

HOGENOM

Q8Z553; -.

Genome annotation databases

CMR

Q8Z553; STY2514.

Other

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Cell inner membrane; Cell membrane; Complete proteome; Flavoprotein; FMN; Membrane; Oxidoreductase.

Features

Feature table viewer

`Key`	`From To`	`Length`		`Description`	`FTId`
`CHAIN`	`1 419`	`419`		`Anaerobic glycerol-3-phosphate dehydrogenase subunit B.`	`PRO_0000204565`

Sequence information

Length: 419 AA [This is the length of the unprocessed precursor]

Molecular weight: 45754 Da [This is the MW of the unprocessed precursor]

CRC64: 407F9BA4032D6274 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MKFDTVIMGG GLAGLLCGLQ LQQHGLRCAI VTRGQSALHF SSGSLDLLSA LPNGQPVTDI 

        70         80         90        100        110        120 
TAGLDALRRQ APEHPYSRLG AQKVLTLAQQ AQTLLNASGA QLYGDVQQAH QRVTPLGTLR 

       130        140        150        160        170        180 
STWLSSPEVP VWPLSAQRIC VVGVSGLLDF QAHLAAASLR QRDLNVETAE IDLPELDVLR 

       190        200        210        220        230        240 
DNPTEFRAVN IARLLDNEEK WQLLYDALSP IATNCDMIIM PACFGLANDT LWRWLNERLP 

       250        260        270        280        290        300 
CALTLLPTLP PSVLGIRLHN QLQRQFVRQG GIWMPGDEVK KVTCRRGTVS EIWTRNHADI 

       310        320        330        340        350        360 
PLRPRFAVLA SGSFFSSGLV AEREGIREPI LGLDVQQTAT RAEWYQQHFF DPQPWQQFGV 

       370        380        390        400        410 
VTDDAFRPSL AGNTVENLYA IGSVLAGFDP IAEGCGGGVC AVSALQAAHH IAERAGEQQ

Q8Z553 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools