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UniProtKB/Swiss-Prot entry Q8PTR0


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name MCH_METMA
Primary accession number Q8PTR0
Secondary accession numbers None
Integrated into Swiss-Prot on October 10, 2002
Sequence was last modified on October 10, 2002 (Sequence version 1)
Annotations were last modified on    November 4, 2008 (Entry version 44)
Name and origin of the protein
Protein name Methenyltetrahydromethanopterin cyclohydrolase
Synonyms EC 3.5.4.27
Methenyl-H4MPT cyclohydrolase
Gene name
Name: mch
OrderedLocusNames: MM_2653
From
Methanosarcina mazei (Methanosarcina frisia) [TaxID: 2209] [HAMAP proteome]
Taxonomy Archaea; Euryarchaeota; Methanomicrobia; Methanosarcinales; Methanosarcinaceae; Methanosarcina.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11883 / OCM 88;
PubMed=12125824 [NCBI, ExPASy, EBI, Israel, Japan]
Deppenmeier U., Johann A., Hartsch T., Merkl R., Schmitz R.A., Martinez-Arias R., Henne A., Wiezer A., Baeumer S., Jacobi C., Brueggemann H., Lienard T., Christmann A., Boemecke M., Steckel S., Bhattacharyya A., Lykidis A., Overbeek R., Klenk H.-P., Gunsalus R.P., Fritz H.-J., Gottschalk G.;
"The genome of Methanosarcina mazei: evidence for lateral gene transfer between Bacteria and Archaea.";
J. Mol. Microbiol. Biotechnol. 4:453-461(2002).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE008384; AAM32349.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_634677.1; -.
3D structure databases
HSSP P94954; 1QLM. [HSSP ENTRY / PDB]
ModBase Q8PTR0.
Enzyme and pathway databases
BioCyc MMAZ192952:MM2653-MON; -.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0018759; Molecular function: methenyltetrahydromethanopterin cyclohydrolase activity (inferred from electronic annotation from HAMAP).
GO:0015948; Biological process: methanogenesis (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
HAMAP MF_00486; -; 1.
PBIL [Tree]
InterPro IPR003209; METHMP_CycOHase.
Graphical view of domain structure.
Pfam PF02289; MCH; 1.
Pfam graphical view of domain structure.
ProDom PD011637; Cyclohydrolase; 1.
[Domain structure / List of seq. sharing at least 1 domain]
TIGRFAMs TIGR03120; one_C_mch; 1.
Genome annotation databases
GeneID 1480995; -.
GenomeReviews AE008384_GR; MM_2653.
KEGG mma:MM_2653; -.
NMPDR fig|192952.1.peg.2653; -.
Phylogenomic databases
HOGENOM Q8PTR0; -.
Genome annotation databases
CMR Q8PTR0; MM_2653.
Other
ProtoNet Q8PTR0.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Cytoplasm; Hydrolase; Methanogenesis; One-carbon metabolism.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   321  321     Methenyltetrahydromethanopterin cyclohydrolase. PRO_0000140883
Sequence information
Length: 321 AA [This is the length of the unprocessed precursor] Molecular weight: 34982 Da [This is the MW of the unprocessed precursor] CRC64: E52D1A7D169FAA8E [This is a checksum on the sequence]
        10         20         30         40         50         60 
MISVNEMGSY VIEEMLDWSE DLKTEVIKLE NGATIIDCGI KAEGGYEAGM YLARLCLADL 

        70         80         90        100        110        120 
ADLKYSTFDL NGIKWPAIQV ATDNPVIACM ASQYAGWRIS VGNYFGMGSG PARALGLKPK 

       130        140        150        160        170        180 
ELYEEIGYED DFEAAVLVME SDKLPDEKVV EYIAKHCSVD PENVMIAVAP TASIAGSVQI 

       190        200        210        220        230        240 
SARVVETGIH KFESIGFDIN CIKSGYGIAP IAPIVGNDVQ CMGSTNDCVI YCGETNYTVS 

       250        260        270        280        290        300 
FEGELAKLED FVRKVPSTTS DDFGKPFYQT FKAANFDFFK VDAGMFAPAR VTVNDLKNKK 

       310        320 
TISSGGLYPE ILLESFGIRK V 

Q8PTR0 in FASTA format

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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
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