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UniProtKB/Swiss-Prot entry Q8P0Z2


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name CITX_STRP8
Primary accession number Q8P0Z2
Secondary accession numbers None
Integrated into Swiss-Prot on November 25, 2002
Sequence was last modified on October 1, 2002 (Sequence version 1)
Annotations were last modified on    September 23, 2008 (Entry version 31)
Name and origin of the protein
Protein name Probable apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
Synonyms EC 2.7.7.61
Holo-ACP synthase
Holo-citrate lyase synthase
Apo-ACP nucleodityltransferase
Gene name
Name: citX
OrderedLocusNames: spyM18_1141
From
Streptococcus pyogenes serotype M18 [TaxID: 301451] [HAMAP proteome]
Taxonomy Bacteria; Firmicutes; Lactobacillales; Streptococcaceae; Streptococcus.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=MGAS8232 / Serotype M18;
DOI=10.1073/pnas.062526099; PubMed=11917108 [NCBI, ExPASy, EBI, Israel, Japan]
Smoot J.C., Barbian K.D., Van Gompel J.J., Smoot L.M., Chaussee M.S., Sylva G.L., Sturdevant D.E., Ricklefs S.M., Porcella S.F., Parkins L.D., Beres S.B., Campbell D.S., Smith T.M., Zhang Q., Kapur V., Daly J.A., Veasy L.G., Musser J.M.;
"Genome sequence and comparative microarray analysis of serotype M18 group A Streptococcus strains associated with acute rheumatic fever outbreaks.";
Proc. Natl. Acad. Sci. U.S.A. 99:4668-4673(2002).
Comments
  • FUNCTION: Transfers 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A on a serine residue to the apo-acyl carrier protein (gamma chain) of the citrate lyase to yield holo-acyl carrier protein (By similarity).
  • CATALYTIC ACTIVITY: 2'-(5-triphosphoribosyl)-3'-dephospho-CoA + citrate lyase apo-[acyl-carrier-protein] = citrate lyase holo-[acyl-carrier-protein] + diphosphate.
  • SIMILARITY: Belongs to the citX family.
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE010039; AAL97761.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_607262.1; -.
3D structure databases
ModBase Q8P0Z2.
Enzyme and pathway databases
BioCyc SPYO186103:SPYM18_1141-MON; -.
Ontologies
GO
GO:0050519; Molecular function: holo-citrate lyase synthase activity (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00398; -; 1.
PBIL [Tree]
InterPro IPR005551; CitX.
Graphical view of domain structure.
Pfam PF03802; CitX; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR03124; ctirate_citX; 1.
Genome annotation databases
GeneID 993940; -.
GenomeReviews AE009949_GR; spyM18_1141.
KEGG spm:spyM18_1141; -.
Phylogenomic databases
HOGENOM Q8P0Z2; -.
Genome annotation databases
CMR Q8P0Z2; spyM18_1141.
Other
ProtoNet Q8P0Z2.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Nucleotidyltransferase; Transferase.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   192  192     Probable apo-citrate lyase phosphoribosyl-dephospho-CoA transferase. PRO_0000214691
Sequence information
Length: 192 AA [This is the length of the unprocessed precursor] Molecular weight: 21506 Da [This is the MW of the unprocessed precursor] CRC64: 97AB5835CC1C3B7C [This is a checksum on the sequence]
        10         20         30         40         50         60 
MCKDTYFSGE AIQLSDMLRA REERALRQLH LLKEYPEGSL LSVTMNIPGP IKTSPKLLEA 

        70         80         90        100        110        120 
FDIVIKAIQT ALADDKICYQ LRLLPTTGYE YYLITSLPSQ DLKLKMIALE TDLPIGRLMD 

       130        140        150        160        170        180 
LDVLVLSNGR PSPISRTTLG APPRQCFICS KEAKVCGRLR KHSVEEMQTA ISKLLHSFFN 

       190 
KDNQSSSSDK TG 

Q8P0Z2 in FASTA format

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BLAST logo BLAST submission on ExPASy/SIB
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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
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NPSA logo NPSA Sequence analysis tools

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