NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1016/S0140-6736(02)08713-5; PubMed=12044378 [NCBI, ExPASy, EBI, Israel, Japan]
Baba T., Takeuchi F., Kuroda M., Yuzawa H., Aoki K., Oguchi A., Nagai Y., Iwama N., Asano K., Naimi T., Kuroda H., Cui L., Yamamoto K., Hiramatsu K.;
"Genome and virulence determinants of high virulence community-acquired MRSA.";
Lancet 359:1819-1827(2002).

Comments

CATALYTIC ACTIVITY: 2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde.
PATHWAY: Carbohydrate degradation; 2-deoxy-D-ribose 1-phosphate degradation; D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose 1-phosphate: step 2/2 .
SUBCELLULAR LOCATION: Cytoplasm (By similarity).
SIMILARITY: Belongs to the deoC/fbaB aldolase family. DeoC type 1 subfamily.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

BA000033; BAB95926.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

RefSeq

NP_646878.1; -.

3D structure databases

HSSP

Q9X1P5; 1O0Y. [HSSP ENTRY / PDB]

ModBase

Q8NVF5.

Enzyme and pathway databases

BioCyc

SAUR196620:MW2061-MON; -.

Ontologies

GO:0005737;	Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0004139;	Molecular function: deoxyribose-phosphate aldolase activity (inferred from electronic annotation from HAMAP).
GO:0016052;	Biological process: carbohydrate catabolic process (inferred from electronic annotation from HAMAP).
GO:0009264;	Biological process: deoxyribonucleotide catabolic process (inferred from electronic annotation from InterPro).
QuickGo view.

Family and domain databases

HAMAP

MF_00114; -; 1.
PBIL [Tree]

InterPro

IPR013785; Aldolase_TIM.
IPR011343; DeoC.
IPR002915; DeoC/AroFGH_arch.
Graphical view of domain structure.

Gene3D

G3DSA:3.20.20.70; Aldolase_TIM; 1.

PANTHER

PTHR10889; DeoC; 1.

Pfam

PF01791; DeoC; 1.
Pfam graphical view of domain structure.

PIRSF

PIRSF001357; DeoC; 1.

TIGRFAMs

TIGR00126; deoC; 1.

Genome annotation databases

GeneID

1004177; -.

GenomeReviews

BA000033_GR; MW2061.

KEGG

sam:MW2061; -.

Phylogenomic databases

HOGENOM

Q8NVF5; -.

Genome annotation databases

CMR

Q8NVF5; MW2061.

Other

ProtoNet

Q8NVF5.

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Complete proteome; Cytoplasm; Lyase; Schiff base.

Features

Feature table viewer

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 220`	`220`	`Deoxyribose-phosphate aldolase 2.`	`PRO_0000057266`
`ACT_SITE`	`151 151`		`Schiff-base intermediate with acetaldehyde (By similarity).`
`ACT_SITE`	`180 180`		`By similarity.`

Sequence information

Length: 220 AA [This is the length of the unprocessed precursor]

Molecular weight: 23336 Da [This is the MW of the unprocessed precursor]

CRC64: 16068532B2A33B06 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MHSAKLIDHT LLKPESTRTQ IDQIIDEAKA YHFKSVCVNP THVKYAAERL ADSEVLVCTV 

        70         80         90        100        110        120 
IGFPLGASTT ATKAFETEDA IQNGADEIDM VINIGALKDG RFDDVQQDIE AVVKAAKGHT 

       130        140        150        160        170        180 
VKVIIETVLL DHDEIVKASE LTKAAGADFV KTSTGFAGGG ATAEDVKLMK DTVGADVEVK 

       190        200        210        220 
ASGGVRNLED FNKMVEAGAT RIGASAGVQI MQGLEADSDY

Q8NVF5 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools