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UniProtKB/Swiss-Prot entry Q8NQ39

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name PYRC_CORGL
Primary accession number Q8NQ39
Secondary accession numbers None
Integrated into Swiss-Prot on February 1, 2003
Sequence was last modified on October 1, 2002 (Sequence version 1)
Annotations were last modified on    December 16, 2008 (Entry version 42)
Name and origin of the protein
Protein name Dihydroorotase
Synonyms DHOase
EC 3.5.2.3
Gene name
Name: pyrC
OrderedLocusNames: Cgl1611, cg1815
From
Corynebacterium glutamicum (Brevibacterium flavum) [TaxID: 1718] [HAMAP proteome]
Taxonomy Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales; Corynebacterineae; Corynebacteriaceae; Corynebacterium.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025;
Nakagawa S.;
"Complete genomic sequence of Corynebacterium glutamicum ATCC 13032.";
Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases.
[2]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025;
DOI=10.1016/S0168-1656(03)00154-8; PubMed=12948626 [NCBI, ExPASy, EBI, Israel, Japan]
Kalinowski J., Bathe B., Bartels D., Bischoff N., Bott M., Burkovski A., Dusch N., Eggeling L., Eikmanns B.J., Gaigalat L., Goesmann A., Hartmann M., Huthmacher K., Kraemer R., Linke B., McHardy A.C., Meyer F., Moeckel B., Pfefferle W., Puehler A., Rey D.A., Rueckert C., Rupp O., Sahm H., Wendisch V.F., Wiegraebe I., Tauch A.;
"The complete Corynebacterium glutamicum ATCC 13032 genome sequence and its impact on the production of L-aspartate-derived amino acids and vitamins.";
J. Biotechnol. 104:5-25(2003).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
BA000036; BAB99004.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
BX927152; CAF21620.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_600825.1; -.
YP_225896.1; -.
3D structure databases
ModBase Q8NQ39.
Enzyme and pathway databases
BioCyc CGLU196627-1:CG1815-MON; -.
Ontologies
GO
GO:0004151; Molecular function: dihydroorotase activity (inferred from electronic annotation from HAMAP).
GO:0008270; Molecular function: zinc ion binding (inferred from electronic annotation from HAMAP).
GO:0006221; Biological process: pyrimidine nucleotide biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00220; -; 1.
PBIL [Tree]
InterPro IPR006680; Amidohydro_1.
IPR004722; DHOmult.
IPR002195; Dihydroorotase_CS.
Graphical view of domain structure.
Pfam PF01979; Amidohydro_1; 1.
Pfam graphical view of domain structure.
ProDom PD000518; DHOase; 1.
[Domain structure / List of seq. sharing at least 1 domain]
TIGRFAMs TIGR00857; pyrC_multi; 1.
PROSITE PS00482; DIHYDROOROTASE_1; 1.
PS00483; DIHYDROOROTASE_2; 1.
Genome annotation databases
GeneID 1019579; -.
3343550; -.
GenomeReviews BA000036_GR; Cgl1611.
BX927147_GR; cg1815.
KEGG cgb:cg1815; -.
cgl:NCgl1549; -.
Phylogenomic databases
HOGENOM Q8NQ39; -.
Genome annotation databases
CMR Q8NQ39; Cgl1611.
Other
ProtoNet Q8NQ39.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Hydrolase; Metal-binding; Pyrimidine biosynthesis; Zinc.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   447  447     Dihydroorotase. PRO_0000147232
METAL   73    73        Zinc 1 (By similarity). 
METAL   75    75        Zinc 1 (By similarity). 
METAL   194   194        Zinc 2 (By similarity). 
METAL   247   247        Zinc 2 (By similarity). 
METAL   320   320        Zinc 1 (By similarity). 
Sequence information
Length: 447 AA [This is the length of the unprocessed precursor] Molecular weight: 47827 Da [This is the MW of the unprocessed precursor] CRC64: 5AAD2377CF5F6572 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MVDSNTQYPE TGALAPAPAD SLLISNVLVY GEGEPTNVFV KDGVIAAIGG THEADRTIDG 

        70         80         90        100        110        120 
NGGVLLPGFV DMHVHLREPG REDTETIATG SAAAAKGGFT AVFTMANTTP VMDQPVIAES 

       130        140        150        160        170        180 
VWFKGQNIGL CDVHPVGSIT KGLEGKELTE FGMMARSEAK VRMFSDDGKC VDDPQVMRRA 

       190        200        210        220        230        240 
LEYAKGMDVL IAQHAEDHRL TEGASAHEGE NAARLGLRGW PRVAEESIVV RDAIMARDYG 

       250        260        270        280        290        300 
NRVHICHAST EGTVELLRWA KSQGIPITAE VTPHHLTLTD ERLETYDAVN KVNPPLRESR 

       310        320        330        340        350        360 
DAEALKKALL DGTIDVVATD HAPHGSEDKC CEFENAKPGM LGLETSLSII VDTFVATGLA 

       370        380        390        400        410        420 
DWRFVARVMS ERPAEITRLP GQGRPIAEGE PANLAIVDPG KTWTASGADF ASKAENTPFE 

       430        440 
GQEFSAKVTH TVLRGKVTCA DGVAQNA
Q8NQ39 in FASTA format

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