[1]	NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Jones P.M., Clarkson J.M., Wheals A.E.; "Acetyl-CoA synthetase 2 of Candida albicans."; Submitted (AUG-2002) to the EMBL/GenBank/DDBJ databases.

Comments

CATALYTIC ACTIVITY: ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA.
SIMILARITY: Belongs to the ATP-dependent AMP-binding enzyme family.

Copyright

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Cross-references

Sequence databases

EMBL

AF535132; AAN01233.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

3D structure databases

ModBase

Q8NJN3.

Ontologies

GO:0003987;	Molecular function: acetate-CoA ligase activity (inferred from electronic annotation from InterPro).
GO:0016208;	Molecular function: AMP binding (inferred from electronic annotation from InterPro).
GO:0008152;	Biological process: metabolic process (inferred from electronic annotation from InterPro).
QuickGo view.

Family and domain databases

InterPro

IPR011904; Ac_CoA_lig_AcsA.
IPR000873; AMP-dep_Synth/Lig.
Graphical view of domain structure.

Pfam

PF00501; AMP-binding; 1.
Pfam graphical view of domain structure.

PRINTS

PR00154; AMPBINDING.

TIGRFAMs

TIGR02188; Ac_CoA_lig_AcsA; 1.

PROSITE

PS00455; AMP_BINDING; 1.

Other

ProtoNet

Q8NJN3.

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Ligase.

Features

Feature table viewer

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 >581`	`>581`	`Acetyl-coenzyme A synthetase 2.`	`PRO_0000208406`
`NON_TER`	`581 581`

Sequence information

Length: 581 AA [This is the length of the partial sequence of the unprocessed precursor]

Molecular weight: 64105 Da [This is the MW of the partial sequence of the unprocessed precursor]

CRC64: E9420D2385DD0943 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MPTEQTHNVV HEANGVKLRE TPKEFFERQP NKGHIHDVNQ YKQMYEQSIK DPQGFFGPLA 

        70         80         90        100        110        120 
KELLSWDHDF HTVKSGTLKN GDAAWFLGGE LNASYNCVDR HAFANPDKPA LICEADDEKD 

       130        140        150        160        170        180 
SHILTYGDLL REVSKVAGVL QSWGIKKGDT VAVYLPMNAQ AIIAMLAIAR LGAAHSVIFA 

       190        200        210        220        230        240 
GFSAGSIKDR VNDASCKALI TCDEGKRGGR TTNIKKLCDE ALVDCPTVEK VLVYKRTNNP 

       250        260        270        280        290        300 
EIHLTEGRDY YWDVETAKFP GYLPPVSVNS EDPLFLLYTS GSTGTPKGVV HSTAGYLLGA 

       310        320        330        340        350        360 
ALSTKYIFDI HPEDILFTAG DVGWITGHTY ALYGPLLLGV PTIIFEGTPA YPDYGRFWQI 

       370        380        390        400        410        420 
VEKHKATHFY VAPTALRLLR KAGEQEIVKY DLSSLRTLGS VGEPISPDIW EWYNEFVGKN 

       430        440        450        460        470        480 
QCHISDTYWQ TESGSHLIAP LAGVVPNKPG SASYPFFGID AALIDPVTGV EIEGNDAEGV 

       490        500        510        520        530        540 
LAIKDHWPSM ARTVYKNHTK YMDTYMNPYP GYYFTGDGAA RDHDGYYWIR GRVDDVVNVS 

       550        560        570        580 
GHRLSTAEIE AALIEDKKVS EAAVVGIHDD ITGQAALLTL P

Q8NJN3 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools