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UniProtKB/Swiss-Prot entry Q8LB01


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name DAPB2_ARATH
Primary accession number Q8LB01
Secondary accession numbers Q3EAH1 Q9M1Y5
Integrated into Swiss-Prot on October 23, 2007
Sequence was last modified on October 1, 2002 (Sequence version 1)
Annotations were last modified on    December 16, 2008 (Entry version 32)
Name and origin of the protein
Protein name Dihydrodipicolinate reductase 2, chloroplastic [Precursor]
Synonyms DHPR 2
EC 1.3.1.26
Gene name
Name: DAPB2
OrderedLocusNames: At3g59890
ORFNames: F24G16.160
From
Arabidopsis thaliana (Mouse-ear cress) [TaxID: 3702] 
Taxonomy Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliophyta; eudicotyledons; core eudicotyledons; rosids; eurosids II; Brassicales; Brassicaceae; Arabidopsis.
Protein existence 2: Evidence at transcript level;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=cv. Columbia;
DOI=10.1038/35048706; PubMed=11130713 [NCBI, ExPASy, EBI, Israel, Japan]
Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B., Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M., Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V., Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P., Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H., Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H., Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A., Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H., Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J., Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B., Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D., de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E., Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G., Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X., Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M., Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B., Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J., Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C., Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y., Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K., Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.;
"Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
Nature 408:820-822(2000).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B., Feldmann K.A.;
"Full-length cDNA from Arabidopsis thaliana.";
Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
[3]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
STRAIN=cv. Columbia;
Quinitio C., Chen H., Kim C.J., Shinn P., Ecker J.R.;
"Arabidopsis ORF Clones.";
Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
[4]
FUNCTION.
DOI=10.1016/j.bbagen.2004.09.008; PubMed=15652176 [NCBI, ExPASy, EBI, Israel, Japan]
Hudson A.O., Bless C., Macedo P., Chatterjee S.P., Singh B.K., Gilvarg C., Leustek T.;
"Biosynthesis of lysine in plants: evidence for a variant of the known bacterial pathways.";
Biochim. Biophys. Acta 1721:27-36(2005).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AL138647; CAB75808.1; ALT_SEQ; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AY087505; AAM65048.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
BT026511; ABH04618.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR T47813; T47813.
RefSeq NP_567088.1; -.
NP_974464.1; -.
UniGene At.34540
3D structure databases
ModBase Q8LB01.
Organism-specific databases
TAIR At3g59890; -.
Ontologies
GO
GO:0009507; Cellular component: chloroplast (inferred from electronic annotation from InterPro).
GO:0005488; Molecular function: binding (inferred from electronic annotation from InterPro).
GO:0008839; Molecular function: dihydrodipicolinate reductase activity (inferred from electronic annotation from InterPro).
GO:0019877; Biological process: diaminopimelate biosynthetic process (inferred from electronic annotation from UniProtKB-KW).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
InterPro IPR000846; DapB.
IPR011770; DapB_bac/pln.
IPR011859; DapB_pln.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
PANTHER PTHR20836; DapB_bac/pln; 1.
Pfam PF05173; DapB_C; 1.
PF01113; DapB_N; 1.
Pfam graphical view of domain structure.
ProDom PD004105; DapB; 1.
[Domain structure / List of seq. sharing at least 1 domain]
TIGRFAMs TIGR02130; dapB_plant; 1.
Proteomics databases
PRIDE Q8LB01; -.
Genome annotation databases
GeneID 825159; -.
GenomeReviews BA000014_GR; AT3G59890.
KEGG ath:AT3G59890; -.
Other
ProtoNet Q8LB01.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Alternative splicing; Amino-acid biosynthesis; Chloroplast; Complete proteome; Diaminopimelate biosynthesis; Lysine biosynthesis; NADP; Oxidoreductase; Plastid; Transit peptide.
Features
SEVIEWER logo Feature table viewer
KeyFrom  To Length Description FTId
TRANSIT   1    53  53     Chloroplast (Potential). 
CHAIN   54   349  296     Dihydrodipicolinate reductase 2, chloroplastic. PRO_0000307183
VAR_SEQ   1     6        Missing (in isoform 2). VSP_028629
Sequence information
Length: 349 AA [This is the length of the unprocessed precursor] Molecular weight: 37870 Da [This is the MW of the unprocessed precursor] CRC64: D7CA92482ECA28CA [This is a checksum on the sequence]
        10         20         30         40         50         60 
MAANGLMAAS SVFLHRPVHP HFSFSSRTNQ MVPLGFKGRV SFIGNVKRCF PVVLSMGKSE 

        70         80         90        100        110        120 
TFEEAGNSVA PGNGISIMVN GCSGKMGKAV IKAADSAGVN IVPTSFGSVE EAGQTVEVCG 

       130        140        150        160        170        180 
KEILVHGPTE REKVLSSVFE KYPELIVVDY TIPSAVNDNA ELYGKVGVPF VMGTTGGDRT 

       190        200        210        220        230        240 
RLYKTVEESK IYAVISPQMG KQVVAFLAAM EIMSEQFPGA FAGYSLEVME SHQASKLDAS 

       250        260        270        280        290        300 
GTAKAVISCF QKLGVSYDMD QIQLIRDPKQ QIEVVGVPEE HVSGHAFHLY HLTSPDKTVS 

       310        320        330        340 
FEFQHNVCGR SIYAEGTVDA VLFLAKKIRS KAEKRIYNMI DVLREGNMR 

Q8LB01 in FASTA format

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