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UniProtKB/Swiss-Prot entry Q8L4Y2


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name LPAT4_ARATH
Primary accession number Q8L4Y2
Secondary accession numbers Q9C9P8 Q9SSH0
Integrated into Swiss-Prot on May 10, 2005
Sequence was last modified on October 1, 2002 (Sequence version 1)
Annotations were last modified on    November 4, 2008 (Entry version 34)
Name and origin of the protein
Protein name Probable 1-acyl-sn-glycerol-3-phosphate acyltransferase 4
Synonyms EC 2.3.1.51
Lysophosphatidyl acyltransferase 4
Gene name
Name: LPAT4
Synonyms: LPAAT4
OrderedLocusNames: At1g75020
ORFNames: F25A4.2
From
Arabidopsis thaliana (Mouse-ear cress) [TaxID: 3702] 
Taxonomy Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliophyta; eudicotyledons; core eudicotyledons; rosids; eurosids II; Brassicales; Brassicaceae; Arabidopsis.
Protein existence 2: Evidence at transcript level;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=cv. Columbia;
DOI=10.1038/35048500; PubMed=11130712 [NCBI, ExPASy, EBI, Israel, Japan]
Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.;
"Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
Nature 408:816-820(2000).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
STRAIN=cv. Columbia;
DOI=10.1126/science.1088305; PubMed=14593172 [NCBI, ExPASy, EBI, Israel, Japan]
Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.;
"Empirical analysis of transcriptional activity in the Arabidopsis genome.";
Science 302:842-846(2003).
[3]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B., Feldmann K.A.;
"Full-length cDNA from Arabidopsis thaliana.";
Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
[4]
TISSUE SPECIFICITY.
DOI=10.1105/tpc.104.030403; PubMed=15772283 [NCBI, ExPASy, EBI, Israel, Japan]
Kim H.U., Li Y., Huang A.H.C.;
"Ubiquitous and endoplasmic reticulum-located lysophosphatidyl acyltransferase, LPAT2, is essential for female but not male gametophyte development in Arabidopsis.";
Plant Cell 17:1073-1089(2005).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AC008263; AAD55275.1; ALT_SEQ; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AC013258; AAG51931.1; ALT_SEQ; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AY099547; AAM20399.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
BT001236; AAN65123.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AY084709; AAM61283.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR B96780; B96780.
RefSeq NP_565098.1; -.
NP_974144.1; -.
UniGene At.43179
3D structure databases
ModBase Q8L4Y2.
Organism-specific databases
TAIR At1g75020; -.
Gene expression databases
ArrayExpress Q8L4Y2; -.
GermOnline AT1G75020; Arabidopsis thaliana.
Ontologies
GO
GO:0016021; Cellular component: integral to membrane (inferred from electronic annotation from UniProtKB-KW).
GO:0003841; Molecular function: 1-acylglycerol-3-phosphate O-acyltransferase activity (inferred from electronic annotation from EC).
GO:0008654; Biological process: phospholipid biosynthetic process (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
InterPro IPR002123; Acyltransferase.
Graphical view of domain structure.
Pfam PF01553; Acyltransferase; 1.
Pfam graphical view of domain structure.
SMART SM00563; PlsC; 1.
SMART graphical view of domain structure.
Genome annotation databases
GeneID 843840; -.
GenomeReviews CT485782_GR; AT1G75020.
KEGG ath:AT1G75020; -.
NMPDR fig|3702.1.peg.7018; -.
Other
ProtoNet Q8L4Y2.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Acyltransferase; Complete proteome; Membrane; Phospholipid biosynthesis; Transferase; Transmembrane.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   378  378     Probable 1-acyl-sn-glycerol-3-phosphate acyltransferase 4. PRO_0000208183
TRANSMEM   26    46  21     Potential. 
TRANSMEM   62    82  21     Potential. 
TRANSMEM   317   337  21     Potential. 
MOTIF   105   110  6     HXXXXD motif. 
Sequence information
Length: 378 AA [This is the length of the unprocessed precursor] Molecular weight: 43064 Da [This is the MW of the unprocessed precursor] CRC64: 36DB41D29E3B7ABC [This is a checksum on the sequence]
        10         20         30         40         50         60 
MEVCGDLKSD NLKNRPLTPL RILRGLMILL VFLSTAFMFL LYFAPIAALG LRLLSVQQSR 

        70         80         90        100        110        120 
KVVSLIFGLW LALWPYLFET VNGTTVVFSG DIIPVEKRVL LIANHRTEVD WMYLWNIALR 

       130        140        150        160        170        180 
KGCLGYIKYV LKSSLMKLPI FGWGFHVLEF IPVERKREVD EPVLLQMLSS FKDPQEPLWL 

       190        200        210        220        230        240 
ALFPEGTDFT EEKCKRSQKF AAEVGLPALS NVLLPKTRGF GVCLEVLHNS LDAVYDLTIA 

       250        260        270        280        290        300 
YKPRCPSFMD NVFGTDPSEV HIHVRRVLLK EIPANEAESS AWLMDSFKLK DKLLSDFNAQ 

       310        320        330        340        350        360 
GKFPNQRPEE ELSVLKCIAT FAGVISLTVV FIYLTLYSHS CFKVYACLSG TYLTFATYYK 

       370 
FQPSPGCFRE DSCKVKNH 

Q8L4Y2 in FASTA format

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