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UniProtKB/Swiss-Prot entry Q8KGD2

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name MURD_CHLTE
Primary accession number Q8KGD2
Secondary accession numbers None
Integrated into Swiss-Prot on April 30, 2003
Sequence was last modified on October 1, 2002 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 47)
Name and origin of the protein
Protein name UDP-N-acetylmuramoylalanine--D-glutamate ligase
Synonyms EC 6.3.2.9
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase
D-glutamic acid-adding enzyme
Gene name
Name: murD
OrderedLocusNames: CT0036
From
Chlorobium tepidum [TaxID: 1097] [HAMAP proteome]
Taxonomy Bacteria; Chlorobi; Chlorobia; Chlorobiales; Chlorobiaceae; Chlorobaculum.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 49652 / DSM 12025 / TLS;
DOI=10.1073/pnas.132181499; PubMed=12093901 [NCBI, ExPASy, EBI, Israel, Japan]
Eisen J.A., Nelson K.E., Paulsen I.T., Heidelberg J.F., Wu M., Dodson R.J., DeBoy R.T., Gwinn M.L., Nelson W.C., Haft D.H., Hickey E.K., Peterson J.D., Durkin A.S., Kolonay J.F., Yang F., Holt I.E., Umayam L.A., Mason T.M., Brenner M., Shea T.P., Parksey D.S., Nierman W.C., Feldblyum T.V., Hansen C.L., Craven M.B., Radune D., Vamathevan J.J., Khouri H.M., White O., Gruber T.M., Ketchum K.A., Venter J.C., Tettelin H., Bryant D.A., Fraser C.M.;
"The complete genome sequence of Chlorobium tepidum TLS, a photosynthetic, anaerobic, green-sulfur bacterium.";
Proc. Natl. Acad. Sci. U.S.A. 99:9509-9514(2002).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE006470; AAM71284.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_660942.1; -.
3D structure databases
HSSP P14900; 2UAG. [HSSP ENTRY / PDB]
ModBase Q8KGD2.
Enzyme and pathway databases
BioCyc CTEP194439:CT_0036-MON; -.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0005524; Molecular function: ATP binding (inferred from electronic annotation from HAMAP).
GO:0008764; Molecular function: UDP-N-acetylmuramoylalanine-D-glutamate ligase activity (inferred from electronic annotation from HAMAP).
GO:0007049; Biological process: cell cycle (inferred from electronic annotation from UniProtKB-KW).
GO:0051301; Biological process: cell division (inferred from electronic annotation from InterPro).
GO:0009252; Biological process: peptidoglycan biosynthetic process (inferred from electronic annotation from HAMAP).
GO:0008360; Biological process: regulation of cell shape (inferred from electronic annotation from InterPro).
QuickGo view.
Family and domain databases
HAMAP MF_00639; -; 1.
PBIL [Tree]
InterPro IPR004101; Mur_ligase_C.
IPR013221; Mur_ligase_cen.
IPR016040; NAD(P)-bd.
IPR005762; UDP-N-AcMur-Glu_ligase.
Graphical view of domain structure.
Gene3D G3DSA:3.90.190.20; Mur_ligase_C; 1.
G3DSA:3.40.1190.10; Mur_ligase_cen; 1.
G3DSA:3.40.50.720; NAD(P)-bd; 1.
Pfam PF02875; Mur_ligase_C; 1.
PF08245; Mur_ligase_M; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR01087; murD; 1.
Genome annotation databases
GeneID 1006454; -.
GenomeReviews AE006470_GR; CT0036.
KEGG cte:CT0036; -.
NMPDR fig|194439.1.peg.36; -.
TIGR CT0036; -.
Phylogenomic databases
HOGENOM Q8KGD2; -.
Other
ProtoNet Q8KGD2.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
ATP-binding; Cell cycle; Cell division; Cell shape; Cell wall biogenesis/degradation; Complete proteome; Cytoplasm; Ligase; Nucleotide-binding; Peptidoglycan synthesis.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   465  465     UDP-N-acetylmuramoylalanine--D-glutamate ligase. PRO_0000108997
NP_BIND   115   121  7     ATP (Potential). 
Sequence information
Length: 465 AA [This is the length of the unprocessed precursor] Molecular weight: 49631 Da [This is the MW of the unprocessed precursor] CRC64: D5DC9676E1DD8EB7 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MKPEELKGKV ASVIGAGKSG VSAAGLLARA GARPFLSEFG AVSPEAAATL RQLGVPFEEG 

        70         80         90        100        110        120 
GHSERVFEAA LCIVSPGIPQ TVPVIREMHA RGIPVVSEIE LASWFCPARI IGITGTDGKT 

       130        140        150        160        170        180 
TTATLLHRIC AAEGERKGFR AFSVGNIGIP FSSEVPGMTA ADIAVLELSS YQLEACFDFR 

       190        200        210        220        230        240 
PNIAVLTNVT PDHMDRYGGS IEAYATAKYR IHARQGAGDT LIYNHDDPIL RAHFDRSEPW 

       250        260        270        280        290        300 
PFRLVRLGLR AETLDVAPGD FVSVEDGEIV VRASGSTERL MRVDEIMKPG FRGEHNLYNA 

       310        320        330        340        350        360 
LSSVAAALAA GVAPETMRGV LAGFGGVEHR QELAGNACGL NWINDSKATS VNALRQALQS 

       370        380        390        400        410        420 
VPAGMVLIAG GRDKGNDYSA IADLVREKVA CIVAIGESRR KIADAFRGVT PVVEAASLAE 

       430        440        450        460 
AVELARQNAR PGASVLFSPA CSSFDMFRDF EDRGRQFKQL VRELT
Q8KGD2 in FASTA format

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