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UniProtKB/Swiss-Prot entry Q8KEX2

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name NADE_CHLTE
Primary accession number Q8KEX2
Secondary accession numbers None
Integrated into Swiss-Prot on November 15, 2002
Sequence was last modified on October 1, 2002 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 37)
Name and origin of the protein
Protein name NH(3)-dependent NAD(+) synthetase
Synonym EC 6.3.1.5
Gene name
Name: nadE
OrderedLocusNames: CT0560
From
Chlorobium tepidum [TaxID: 1097] [HAMAP proteome]
Taxonomy Bacteria; Chlorobi; Chlorobia; Chlorobiales; Chlorobiaceae; Chlorobaculum.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 49652 / DSM 12025 / TLS;
DOI=10.1073/pnas.132181499; PubMed=12093901 [NCBI, ExPASy, EBI, Israel, Japan]
Eisen J.A., Nelson K.E., Paulsen I.T., Heidelberg J.F., Wu M., Dodson R.J., DeBoy R.T., Gwinn M.L., Nelson W.C., Haft D.H., Hickey E.K., Peterson J.D., Durkin A.S., Kolonay J.F., Yang F., Holt I.E., Umayam L.A., Mason T.M., Brenner M., Shea T.P., Parksey D.S., Nierman W.C., Feldblyum T.V., Hansen C.L., Craven M.B., Radune D., Vamathevan J.J., Khouri H.M., White O., Gruber T.M., Ketchum K.A., Venter J.C., Tettelin H., Bryant D.A., Fraser C.M.;
"The complete genome sequence of Chlorobium tepidum TLS, a photosynthetic, anaerobic, green-sulfur bacterium.";
Proc. Natl. Acad. Sci. U.S.A. 99:9509-9514(2002).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE006470; AAM71802.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_661460.1; -.
3D structure databases
HSSP P08164; 1IFX. [HSSP ENTRY / PDB]
ModBase Q8KEX2.
Enzyme and pathway databases
BioCyc CTEP194439:CT_0560-MON; -.
Ontologies
GO
GO:0005524; Molecular function: ATP binding (inferred from electronic annotation from HAMAP).
GO:0003952; Molecular function: NAD+ synthase (glutamine-hydrolyzing) activity (inferred from electronic annotation from InterPro).
GO:0008795; Molecular function: NAD+ synthase activity (inferred from electronic annotation from EC).
GO:0009435; Biological process: NAD biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00193; -; 1.
PBIL [Tree]
InterPro IPR003694; NAD_synthase.
IPR014729; Rossmann-like_a/b/a_fold.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.620; Rossmann-like_a/b/a_fold; 1.
Pfam PF02540; NAD_synthase; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR00552; nadE; 1.
Genome annotation databases
GeneID 1006143; -.
GenomeReviews AE006470_GR; CT0560.
KEGG cte:CT0560; -.
NMPDR fig|194439.1.peg.554; -.
TIGR CT0560; -.
Phylogenomic databases
HOGENOM Q8KEX2; -.
Other
ProtoNet Q8KEX2.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
ATP-binding; Complete proteome; Ligase; NAD; Nucleotide-binding.
Features
SEVIEWER logo Feature table viewer
KeyFrom  To Length Description FTId
CHAIN   1   277  277     NH(3)-dependent NAD(+) synthetase. PRO_0000152163
NP_BIND   36    43  8     ATP (By similarity). 
ACT_SITE   38    38        By similarity. 
Sequence information
Length: 277 AA [This is the length of the unprocessed precursor] Molecular weight: 31125 Da [This is the MW of the unprocessed precursor] CRC64: CBEBD73BE5A462E2 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MKPQNLHFDY GLVEAILVPF IRNEIRKFGF GSVVLGLSGG IDSAVVCELA VRALGVENVL 

        70         80         90        100        110        120 
ALMMPYKTSS QESLDHAELM VDRLGIRYEI MPVTEVVDAF FATRPDASRL RRGNVMARSR 

       130        140        150        160        170        180 
MLCLYDVSAR DGCLVLGTSN KTELMLGYGT MFGDMASAVN PIGDLYKTQI FGLARHLGIP 

       190        200        210        220        230        240 
APLIDKPPSA DLWEGQSDEA DLGFSYEEVD QLLYMMLEER MDRDAILAEG IDSAFYQRVR 

       250        260        270 
SMVVRNQYKR MMPVIAKLSS RTPGIDFRYA RDWQEVR
Q8KEX2 in FASTA format

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