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UniProtKB/Swiss-Prot entry Q8KA60

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name ASSY_BUCAP
Primary accession number Q8KA60
Secondary accession numbers None
Integrated into Swiss-Prot on November 8, 2002
Sequence was last modified on October 1, 2002 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 46)
Name and origin of the protein
Protein name Argininosuccinate synthase
Synonyms EC 6.3.4.5
Citrulline--aspartate ligase
Gene name
Name: argG
OrderedLocusNames: BUsg_047
From
Buchnera aphidicola subsp. Schizaphis graminum [TaxID: 98794] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Buchnera.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1126/science.1071278; PubMed=12089438 [NCBI, ExPASy, EBI, Israel, Japan]
Tamas I., Klasson L., Canbaeck B., Naeslund A.K., Eriksson A.-S., Wernegreen J.J., Sandstroem J.P., Moran N.A., Andersson S.G.E.;
"50 million years of genomic stasis in endosymbiotic bacteria.";
Science 296:2376-2379(2002).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE013218; AAM67618.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_660407.1; -.
3D structure databases
ModBase Q8KA60.
Enzyme and pathway databases
BioCyc BAPH198804:BUSG047-MON; -.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0004055; Molecular function: argininosuccinate synthase activity (inferred from electronic annotation from HAMAP).
GO:0005524; Molecular function: ATP binding (inferred from electronic annotation from HAMAP).
GO:0006526; Biological process: arginine biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00005; -; 1.
PBIL [Tree]
InterPro IPR001518; Arginosuc_synth.
IPR014729; Rossmann-like_a/b/a_fold.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.620; Rossmann-like_a/b/a_fold; 1.
PANTHER PTHR11587; Arginosuc_synth; 1.
Pfam PF00764; Arginosuc_synth; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR00032; argG; 1.
PROSITE PS00564; ARGININOSUCCIN_SYN_1; 1.
PS00565; ARGININOSUCCIN_SYN_2; 1.
Genome annotation databases
GeneID 1005863; -.
GenomeReviews AE013218_GR; BUsg_047.
KEGG bas:BUsg047; -.
Phylogenomic databases
HOGENOM Q8KA60; -.
Genome annotation databases
CMR Q8KA60; BUsg_047.
Other
ProtoNet Q8KA60.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Amino-acid biosynthesis; Arginine biosynthesis; ATP-binding; Complete proteome; Cytoplasm; Ligase; Nucleotide-binding.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   401  401     Argininosuccinate synthase. PRO_0000148577
NP_BIND   10    18  9     ATP (By similarity). 
BINDING   37    37        ATP; via amide nitrogen and carbonyl oxygen (By similarity). 
BINDING   89    89        Citrulline (By similarity). 
BINDING   119   119        ATP; via amide nitrogen (By similarity). 
BINDING   121   121        Aspartate (By similarity). 
BINDING   125   125        Aspartate (By similarity). 
BINDING   125   125        Citrulline (By similarity). 
BINDING   126   126        Aspartate (By similarity). 
BINDING   129   129        Citrulline (By similarity). 
BINDING   178   178        Citrulline (By similarity). 
BINDING   187   187        Citrulline (By similarity). 
BINDING   263   263        Citrulline (By similarity). 
BINDING   275   275        Citrulline (By similarity). 
Sequence information
Length: 401 AA [This is the length of the unprocessed precursor] Molecular weight: 45124 Da [This is the MW of the unprocessed precursor] CRC64: 16DD4B6F98E13D8C [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MNNFKKVVLA YSGGLDTSAI IPWLKENYHV DVVAFVADIG QSKKDLNGIE KKALQSGAID 

        70         80         90        100        110        120 
CRVFDLKEEF IKDYVYPVLK TGSLYEGNYL LGTAIARPII AKKQVEFASS IGAKFLCHGA 

       130        140        150        160        170        180 
TGKGNDQVRF EIAYAALAPY MKVIAPWREW NLNSRESLLE YLREKNIPTS ATLEKIYSRD 

       190        200        210        220        230        240 
ENSLHISTEG GLLEDLWNKP NADCWNWTVE LEDAPEQPEY ISLIVKNGSV VSVNNEFLTP 

       250        260        270        280        290        300 
LKCIEKLNKI GSKHAIGRID IVENRLVGIK SRGCYETPGG TIMHIALRAI EQLVFDRESF 

       310        320        330        340        350        360 
KWREKIGLEM SSVVYDGRWF TPIRKSLQAS ADSLSSEVNG EVVLKLYKGS VIPVQKKSSN 

       370        380        390        400 
SLYSKEYATF GEDEVYKHSD AEGFIRLFSL SSRIRAQNKL K
Q8KA60 in FASTA format

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