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UniProtKB/Swiss-Prot entry Q8K9N0

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name K6PF_BUCAP
Primary accession number Q8K9N0
Secondary accession numbers None
Integrated into Swiss-Prot on November 8, 2002
Sequence was last modified on October 1, 2002 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 43)
Name and origin of the protein
Protein name 6-phosphofructokinase
Synonyms Phosphofructokinase
EC 2.7.1.11
Phosphohexokinase
Gene name
Name: pfkA
OrderedLocusNames: BUsg_295
From
Buchnera aphidicola subsp. Schizaphis graminum [TaxID: 98794] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Buchnera.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1126/science.1071278; PubMed=12089438 [NCBI, ExPASy, EBI, Israel, Japan]
Tamas I., Klasson L., Canbaeck B., Naeslund A.K., Eriksson A.-S., Wernegreen J.J., Sandstroem J.P., Moran N.A., Andersson S.G.E.;
"50 million years of genomic stasis in endosymbiotic bacteria.";
Science 296:2376-2379(2002).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE013218; AAM67850.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_660639.1; -.
3D structure databases
HSSP P06998; 2PFK. [HSSP ENTRY / PDB]
SMR Q8K9N0; 1-320.
ModBase Q8K9N0.
Enzyme and pathway databases
BioCyc BAPH198804:BUSG295-MON; -.
Ontologies
GO
GO:0005945; Cellular component: 6-phosphofructokinase complex (inferred from electronic annotation from InterPro).
GO:0003872; Molecular function: 6-phosphofructokinase activity (inferred from electronic annotation from HAMAP).
GO:0005524; Molecular function: ATP binding (inferred from electronic annotation from InterPro).
GO:0000287; Molecular function: magnesium ion binding (inferred from electronic annotation from UniProtKB-KW).
GO:0006002; Biological process: fructose 6-phosphate metabolic process (inferred from electronic annotation from InterPro).
GO:0006096; Biological process: glycolysis (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00339; -; 1.
PBIL [Tree]
InterPro IPR012003; ATP_PFK_prok.
IPR012828; PFKA_ATP.
IPR015912; Phosphofructokinase_CS.
IPR000023; Ppfruckinase.
Graphical view of domain structure.
PANTHER PTHR13697; Ppfruckinase; 1.
Pfam PF00365; PFK; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000532; ATP_PFK_prok; 1.
PRINTS PR00476; PHFRCTKINASE.
ProDom PD000707; Ppfruckinase; 1.
[Domain structure / List of seq. sharing at least 1 domain]
TIGRFAMs TIGR02482; PFKA_ATP; 1.
PROSITE PS00433; PHOSPHOFRUCTOKINASE; 1.
Genome annotation databases
GeneID 1005499; -.
GenomeReviews AE013218_GR; BUsg_295.
KEGG bas:BUsg295; -.
Phylogenomic databases
HOGENOM Q8K9N0; -.
Genome annotation databases
CMR Q8K9N0; BUsg_295.
Other
ProtoNet Q8K9N0.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Allosteric enzyme; ATP-binding; Complete proteome; Cytoplasm; Glycolysis; Kinase; Magnesium; Metal-binding; Nucleotide-binding; Transferase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   320  320     6-phosphofructokinase. PRO_0000111941
NP_BIND   22    26  5     ATP (By similarity). 
NP_BIND   155   159  5     ATP (By similarity). 
NP_BIND   172   188  17     ATP (By similarity). 
ACT_SITE   128   128        Proton acceptor (By similarity). 
METAL   186   186        Magnesium; via carbonyl oxygen (By similarity). 
METAL   188   188        Magnesium (By similarity). 
BINDING   163   163        Substrate (By similarity). 
BINDING   244   244        Substrate (By similarity). 
BINDING   250   250        Substrate (By similarity). 
BINDING   253   253        Substrate (By similarity). 
Sequence information
Length: 320 AA [This is the length of the unprocessed precursor] Molecular weight: 35239 Da [This is the MW of the unprocessed precursor] CRC64: FA57FB8507548ED1 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MIKKIGVLTS GGDAPGMNAA IRGVVRTALS EKLEVFGIYD GYLGLYENRM TLLDRYSVSD 

        70         80         90        100        110        120 
MINRGGTFLG SARFPGFYKN EIRTIAVNNL NKRNIDALVV IGGDGSYIGA QKLTKMGIPC 

       130        140        150        160        170        180 
ISIPGTIDND VAGTDYTIGY FTALETVVEA IDRLRDTSSS HQRISIVEVM GRYCGDLTLA 

       190        200        210        220        230        240 
AAIAGGCEFI VLPEIHYKKE ELVSEIQAGI EKGKKHAIVA ITEYICDVEK LAKYIEKKTN 

       250        260        270        280        290        300 
RETRATILGH IQRGGAPVVY DRILASRMGA YAVELLIEGY KGKCVGIQNE KMVFNDITDA 

       310        320 
LKNMKRVFKK DWLITAKKLY
Q8K9N0 in FASTA format

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