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UniProtKB/Swiss-Prot entry Q8K2A8

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name ALG3_MOUSE
Primary accession number Q8K2A8
Secondary accession numbers None
Integrated into Swiss-Prot on January 4, 2005
Sequence was last modified on October 1, 2002 (Sequence version 1)
Annotations were last modified on    December 16, 2008 (Entry version 39)
Name and origin of the protein
Protein name Dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase
Synonyms EC 2.4.1.130
Dol-P-Man-dependent alpha(1-3)-mannosyltransferase
Dolichyl-phosphate-mannose--glycolipid alpha-mannosyltransferase
Asparagine-linked glycosylation protein 3
Not56-like protein
Gene name
Name: Alg3
Synonyms: Not, Not56l
From
Mus musculus (Mouse) [TaxID: 10090] 
Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus.
Protein existence 2: Evidence at transcript level;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
STRAIN=FVB/N-3;
TISSUE=Mammary tumor;
DOI=10.1101/gr.2596504; PubMed=15489334 [NCBI, ExPASy, EBI, Israel, Japan]
The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
BC031893; AAH31893.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_666051.1; -.
UniGene Mm.24950
3D structure databases
ModBase Q8K2A8.
PTM databases
PhosphoSite Q8K2A8; -.
Organism-specific databases
MGI MGI:1098592; Alg3.
Gene expression databases
GermOnline ENSMUSG00000033809; Mus musculus.
Ontologies
GO
GO:0005789; Cellular component: endoplasmic reticulum membrane (inferred from electronic annotation from UniProtKB-SubCell).
GO:0016021; Cellular component: integral to membrane (inferred from electronic annotation from InterPro).
GO:0004584; Molecular function: dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity (inferred from electronic annotation from EC).
QuickGo view.
Family and domain databases
InterPro IPR007873; ALG3.
Graphical view of domain structure.
PANTHER PTHR12646; ALG3; 1.
Pfam PF05208; ALG3; 1.
Pfam graphical view of domain structure.
Genome annotation databases
Ensembl ENSMUSG00000033809; Mus musculus. [Contig view]
GeneID 208624; -.
KEGG mmu:208624; -.
Phylogenomic databases
HOGENOM Q8K2A8; -.
HOVERGEN Q8K2A8; -.
Other
NextBio 372337; -.
SOURCE Alg3; Mus musculus.
ProtoNet Q8K2A8.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Endoplasmic reticulum; Glycosyltransferase; Membrane; Phosphoprotein; Transferase; Transmembrane.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   438  438     Dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase. PRO_0000080567
TRANSMEM   41    61  21     Potential. 
TRANSMEM   95   115  21     Potential. 
TRANSMEM   123   143  21     Potential. 
TRANSMEM   149   169  21     Potential. 
TRANSMEM   172   192  21     Potential. 
TRANSMEM   203   223  21     Potential. 
TRANSMEM   231   251  21     Potential. 
TRANSMEM   289   309  21     Potential. 
TRANSMEM   332   352  21     Potential. 
TRANSMEM   356   376  21     Potential. 
TRANSMEM   407   427  21     Potential. 
MOD_RES   13    13        Phosphoserine (By similarity). 
Sequence information
Length: 438 AA [This is the length of the unprocessed precursor] Molecular weight: 50166 Da [This is the MW of the unprocessed precursor] CRC64: 99297B2F51F6330F [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MAAGLRKRGQ PASVGQPAGI WKQWLQRAWQ ERYLLLREPR YTLLVASCLC IAEVGITFWV 

        70         80         90        100        110        120 
IHRVAYTEID WKAYMAQVEG FINGTYDYTQ LQGDTGPLVY PAGFLYIFTG LFYATDRGTD 

       130        140        150        160        170        180 
IPMAQNIFAV LYLVTLVLVF LIYHQTSKVP PFVFFFMCCA SYRVHSIFVL RLFNDPVAMA 

       190        200        210        220        230        240 
LLFLSINLFL AQCWSWGCCC FSLAVSVKMN VLLFAPGLLF LLLTQFGFRG ALPKLAICAA 

       250        260        270        280        290        300 
LQVVLGLPFL LENPIGYLSR SFDLGRQFLF QWTVNWRFLP ETIFLHRAFH LALLAAHLSL 

       310        320        330        340        350        360 
LLLFALCRWH RTGESILALL KDPSKRKVPP QALTPNQIVS ILFTSNFIGI CFSHSLHYQF 

       370        380        390        400        410        420 
YVWYFHTLPY LLWAMPARWL THLLRLLVLG LIELSWNTYP STSFSSAALH LCHAVVLLQL 

       430 
WLSPESFPKS IQPSRKTH
Q8K2A8 in FASTA format

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