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UniProtKB/Swiss-Prot entry Q8FKI9

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name BETA_ECOL6
Primary accession number Q8FKI9
Secondary accession numbers None
Integrated into Swiss-Prot on February 16, 2004
Sequence was last modified on February 16, 2004 (Sequence version 2)
Annotations were last modified on    November 25, 2008 (Entry version 44)
Name and origin of the protein
Protein name Choline dehydrogenase
Synonyms CHD
CDH
EC 1.1.99.1
Gene name
Name: betA
OrderedLocusNames: c0431
From
Escherichia coli O6 [TaxID: 217992] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Escherichia.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=O6:H1 / CFT073 / ATCC 700928 / UPEC;
DOI=10.1073/pnas.252529799; PubMed=12471157 [NCBI, ExPASy, EBI, Israel, Japan]
Welch R.A., Burland V., Plunkett G. III, Redford P., Roesch P., Rasko D., Buckles E.L., Liou S.-R., Boutin A., Hackett J., Stroud D., Mayhew G.F., Rose D.J., Zhou S., Schwartz D.C., Perna N.T., Mobley H.L.T., Donnenberg M.S., Blattner F.R.;
"Extensive mosaic structure revealed by the complete genome sequence of uropathogenic Escherichia coli.";
Proc. Natl. Acad. Sci. U.S.A. 99:17020-17024(2002).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE014075; AAN78912.1; ALT_INIT; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_752368.2; -.
3D structure databases
ModBase Q8FKI9.
Ontologies
GO
GO:0005886; Cellular component: plasma membrane (inferred from electronic annotation from UniProtKB-KW).
GO:0008812; Molecular function: choline dehydrogenase activity (inferred from electronic annotation from HAMAP).
GO:0050660; Molecular function: FAD binding (inferred from electronic annotation from InterPro).
GO:0006066; Biological process: cellular alcohol metabolic process (inferred from electronic annotation from InterPro).
GO:0019285; Biological process: glycine betaine biosynthetic process from choline (inferred from electronic annotation from HAMAP).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
HAMAP MF_00750; -; 1.
PBIL [Tree]
InterPro IPR011533; Choline_dehydrogenase.
IPR012132; GMC_OxRdtase.
IPR000172; GMC_OxRdtase_N.
IPR007867; GMC_OxRtase_C.
Graphical view of domain structure.
Pfam PF05199; GMC_oxred_C; 1.
PF00732; GMC_oxred_N; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000137; Alcohol_oxidase; 1.
TIGRFAMs TIGR01810; betA; 1.
PROSITE PS00623; GMC_OXRED_1; 1.
PS00624; GMC_OXRED_2; 1.
Genome annotation databases
GeneID 1036260; -.
GenomeReviews AE014075_GR; c0431.
KEGG ecc:c0431; -.
NMPDR fig|199310.1.peg.412; -.
Phylogenomic databases
HOGENOM Q8FKI9; -.
Genome annotation databases
CMR Q8FKI9; c0431.
Other
ProtoNet Q8FKI9.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Cell membrane; Complete proteome; FAD; Flavoprotein; Membrane; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   556  556     Choline dehydrogenase. PRO_0000205588
NP_BIND   4    33  30     FAD (Probable). 
ACT_SITE   473   473        By similarity. 
Sequence information
Length: 556 AA [This is the length of the unprocessed precursor] Molecular weight: 61899 Da [This is the MW of the unprocessed precursor] CRC64: 7958C0BD6D20BFC1 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MQFDYIIIGA GSAGNVLATR LTEDPNTTVL LLEAGGPDYR FDFRTQMPAA LAFPLQGKRY 

        70         80         90        100        110        120 
NWAYETEPEP FMNNRRMECG RGKGLGGSSL INGMCYIRGN ALDLDNWAQE PSLENWSYLD 

       130        140        150        160        170        180 
CLPYYRKAET RDVGENDYHG GDGPVSVTTS KPGVNPLFEA MIEAGMQAGY PRTDDLNGYQ 

       190        200        210        220        230        240 
QEGFGPMDRT VTPHGRRAST ARGYLDQAKS RPNLTIRTHA MTDHIIFDGK RAVGVEWLEG 

       250        260        270        280        290        300 
DSTIPTRAAA NKEVLLCAGA IASPQILQRS GVGNAELLAE FDIPLVHELP GVGENLQDHL 

       310        320        330        340        350        360 
EMYLQYECKE PVSLYPALQW WNQPRIGAEW LFGGTGVGAS NHFEAGGFIR SREEFAWPNI 

       370        380        390        400        410        420 
QYHFLPVAIN YNGSNAVKEH GFQCHVGSMR SPSRGHVRIK SRDPHQHPGI LFNYMSHEQD 

       430        440        450        460        470        480 
WQEFRDAIRI TREIMHQPAL DQYRGREISP GVECQTDEQL DEFVRNHAET AFHPCGTCKM 

       490        500        510        520        530        540 
GYDEMAVVDG EGRVHGLEGL RVVDASIMPQ IITGNLNATT IMIGEKIADM IRGKEALPRS 

       550 
TAGYFVANGM PVRAKK
Q8FKI9 in FASTA format

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