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UniProtKB/Swiss-Prot entry Q8FH01

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name ASTD_ECOL6
Primary accession number Q8FH01
Secondary accession numbers None
Integrated into Swiss-Prot on November 28, 2006
Sequence was last modified on March 1, 2003 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 44)
Name and origin of the protein
Protein name N-succinylglutamate 5-semialdehyde dehydrogenase
Synonyms EC 1.2.1.71
Succinylglutamic semialdehyde dehydrogenase
SGSD
Gene name
Name: astD
OrderedLocusNames: c2146
From
Escherichia coli O6 [TaxID: 217992] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Escherichia.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=O6:H1 / CFT073 / ATCC 700928 / UPEC;
DOI=10.1073/pnas.252529799; PubMed=12471157 [NCBI, ExPASy, EBI, Israel, Japan]
Welch R.A., Burland V., Plunkett G. III, Redford P., Roesch P., Rasko D., Buckles E.L., Liou S.-R., Boutin A., Hackett J., Stroud D., Mayhew G.F., Rose D.J., Zhou S., Schwartz D.C., Perna N.T., Mobley H.L.T., Donnenberg M.S., Blattner F.R.;
"Extensive mosaic structure revealed by the complete genome sequence of uropathogenic Escherichia coli.";
Proc. Natl. Acad. Sci. U.S.A. 99:17020-17024(2002).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE014075; AAN80605.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_754040.1; -.
3D structure databases
ModBase Q8FH01.
Ontologies
GO
GO:0043824; Molecular function: succinylglutamate-semialdehyde dehydrogenase activity (inferred from electronic annotation from InterPro).
GO:0019544; Biological process: arginine catabolic process to glutamate (inferred from electronic annotation from HAMAP).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
HAMAP MF_01174; -; 1.
PBIL [Tree]
InterPro IPR016160; Ald_DHase_CS.
IPR016162; Ald_DHase_N.
IPR015590; Aldehyde_DHase.
IPR017649; SuccinylGlu_semiald_DH_AstD.
Graphical view of domain structure.
Gene3D G3DSA:3.40.605.10; Aldehyde_dehydrogenase_N; 1.
PANTHER PTHR11699; Aldehyde_dehyd; 1.
Pfam PF00171; Aldedh; 1.
Pfam graphical view of domain structure.
PROSITE PS00070; ALDEHYDE_DEHYDR_CYS; 1.
PS00687; ALDEHYDE_DEHYDR_GLU; 1.
Genome annotation databases
GeneID 1036571; -.
GenomeReviews AE014075_GR; c2146.
KEGG ecc:c2146; -.
NMPDR fig|199310.1.peg.2083; -.
Phylogenomic databases
HOGENOM Q8FH01; -.
Genome annotation databases
CMR Q8FH01; c2146.
Other
ProtoNet Q8FH01.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Arginine metabolism; Complete proteome; NAD; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   492  492     N-succinylglutamate 5-semialdehyde dehydrogenase. PRO_0000262401
NP_BIND   220   225  6     NAD (By similarity). 
ACT_SITE   243   243        By similarity. 
ACT_SITE   277   277        By similarity. 
Sequence information
Length: 492 AA [This is the length of the unprocessed precursor] Molecular weight: 52987 Da [This is the MW of the unprocessed precursor] CRC64: E40838B4D2F8E6E4 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MTLWINGDWV TGQGALRVKR NPVSGEVLWQ GNDADAAQVG QACRAARAAF PRWARLSFGD 

        70         80         90        100        110        120 
RQVRVERFAG LLESNKAELT AIIARETGKP RWEAATEVTA MINKIAISIK AYHVRTGEQR 

       130        140        150        160        170        180 
SEMPDGAASL RHRPHGVLAV FGPYNFPGHL PNGHIVPALL AGNTIIFKPS ELTPWSGEAV 

       190        200        210        220        230        240 
MRLWQQAGLP PGVLNLVQGG RATGQALSAL EDLDGLLFTG SANTGYQLHR QLSGQPEKIL 

       250        260        270        280        290        300 
ALEMGGNNPL IIDEVADIDA AVHLTIQSAF VTAGQRCTCA RRLFLKSGTQ GDAFLARMVA 

       310        320        330        340        350        360 
VSQRLTPGTW DDEPQPFIGG LISEQAAQQV VTAWQELEAM GGRTLLAPRL LQAGTSLLTP 

       370        380        390        400        410        420 
GIIEMTGVTG VPDEEVFGPL LRVWRYDNFD EAIRMANNTR FGLSCGLVSP EREKFDQLLL 

       430        440        450        460        470        480 
GARAGIVNWN KPLTGAASTA PFGGIGASGN HRPSAWYAAD YCAWPMASLE SDSLTLPATL 

       490 
NPGLDFSDEV VR
Q8FH01 in FASTA format

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