NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=DSM 14371 / JCM 11309 / KCTC 3954 / HTE831;
DOI=10.1093/nar/gkf526; PubMed=12235376 [NCBI, ExPASy, EBI, Israel, Japan]
Takami H., Takaki Y., Uchiyama I.;
"Genome sequence of Oceanobacillus iheyensis isolated from the Iheya Ridge and its unexpected adaptive capabilities to extreme environments.";
Nucleic Acids Res. 30:3927-3935(2002).

Comments

FUNCTION: Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity).
CATALYTIC ACTIVITY: ATP + NAD⁺ = ADP + NADP⁺.
COFACTOR: Divalent metal ions (By similarity).
SUBCELLULAR LOCATION: Cytoplasm (By similarity).
SIMILARITY: Belongs to the NAD kinase family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

BA000028; BAC13177.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

RefSeq

NP_692142.1; -.

3D structure databases

ModBase

Q8ERS9.

Enzyme and pathway databases

BioCyc

OIHE221109:OB1221-MON; -.

Ontologies

GO:0005737;	Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0046872;	Molecular function: metal ion binding (inferred from electronic annotation from HAMAP).
GO:0003951;	Molecular function: NAD+ kinase activity (inferred from electronic annotation from HAMAP).
GO:0008152;	Biological process: metabolic process (inferred from electronic annotation from InterPro).
QuickGo view.

Family and domain databases

HAMAP

MF_00361; -; 1.
PBIL [Tree]

InterPro

IPR017437; ATP-NAD_kinase_PpnK-typ_all-b.
IPR002504; ATP_NADK.
Graphical view of domain structure.

Gene3D

G3DSA:2.60.200.30; ATP-NAD_kinase_PpnK-typ; 1.

PANTHER

PTHR20275; ATP_NADK; 1.

Pfam

PF01513; NAD_kinase; 1.
Pfam graphical view of domain structure.

Genome annotation databases

1017393; -.

BA000028_GR; OB1221.

oih:OB1221; -.

fig|221109.1.peg.1220; -.

Phylogenomic databases

HOGENOM

Q8ERS9; -.

Genome annotation databases

CMR

Q8ERS9; OB1221.

Other

ProtoNet

Q8ERS9.

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Complete proteome; Cytoplasm; Kinase; NAD; NADP; Transferase.

Features

Feature table viewer

`Key`	`From To`	`Length`		`Description`	`FTId`
`CHAIN`	`1 267`	`267`		`Probable inorganic polyphosphate/ATP-NAD kinase 1.`	`PRO_0000120642`

Sequence information

Length: 267 AA [This is the length of the unprocessed precursor]

Molecular weight: 30240 Da [This is the MW of the unprocessed precursor]

CRC64: A76087334F01B60A [This is a checksum on the sequence]

        10         20         30         40         50         60 
MNFKIVSKGD DRSEKIKAMM RQYLSEFGLT YDKETPDLVI SVGGDGTFLE AFHRYVHRLE 

        70         80         90        100        110        120 
DTAFIGIHTG HLGFYTDWTP KDVERLIIEI AKTPFQTVEY PLLEVIIRAK AGGKEDRILA 

       130        140        150        160        170        180 
LNEAMIKTAD GSSVVFDVEI KGEHFETFRG DGICISTPSG STAYNKALGG AILHPSLEAI 

       190        200        210        220        230        240 
QITENASINN RVFRTIGSPL ILPKHHTCFL KPMVDSSFLI QIDHFTKNYQ NVKSIQCRVA 

       250        260 
KEKVRFARFK QFPFWNRVRD SFVSEEG

Q8ERS9 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools