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UniProtKB/Swiss-Prot entry Q8EB00

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name CYSI_SHEON
Primary accession number Q8EB00
Secondary accession numbers None
Integrated into Swiss-Prot on September 13, 2005
Sequence was last modified on March 1, 2003 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 35)
Name and origin of the protein
Protein name Sulfite reductase [NADPH] hemoprotein beta-component
Synonyms SIR-HP
SIRHP
EC 1.8.1.2
Gene name
Name: cysI
OrderedLocusNames: SO_3737
From
Shewanella oneidensis [TaxID: 70863] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Alteromonadales; Shewanellaceae; Shewanella.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=MR-1;
DOI=10.1038/nbt749; PubMed=12368813 [NCBI, ExPASy, EBI, Israel, Japan]
Heidelberg J.F., Paulsen I.T., Nelson K.E., Gaidos E.J., Nelson W.C., Read T.D., Eisen J.A., Seshadri R., Ward N.L., Methe B.A., Clayton R.A., Meyer T., Tsapin A., Scott J., Beanan M.J., Brinkac L.M., Daugherty S.C., DeBoy R.T., Dodson R.J., Durkin A.S., Haft D.H., Kolonay J.F., Madupu R., Peterson J.D., Umayam L.A., White O., Wolf A.M., Vamathevan J.J., Weidman J.F., Impraim M., Lee K., Berry K.J., Lee C., Mueller J., Khouri H.M., Gill J., Utterback T.R., McDonald L.A., Feldblyum T.V., Smith H.O., Venter J.C., Nealson K.H., Fraser C.M.;
"Genome sequence of the dissimilatory metal ion-reducing bacterium Shewanella oneidensis.";
Nat. Biotechnol. 20:1118-1123(2002).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE014299; AAN56720.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_719276.1; -.
3D structure databases
HSSP P17846; 1AOP. [HSSP ENTRY / PDB]
ModBase Q8EB00.
Enzyme and pathway databases
BioCyc SONE211586:SO_3737-MON; -.
Ontologies
GO
GO:0009337; Cellular component: sulfite reductase complex (NADPH) (inferred from electronic annotation from InterPro).
GO:0051539; Molecular function: 4 iron, 4 sulfur cluster binding (inferred from electronic annotation from InterPro).
GO:0009055; Molecular function: electron carrier activity (inferred from electronic annotation from InterPro).
GO:0020037; Molecular function: heme binding (inferred from electronic annotation from InterPro).
GO:0005506; Molecular function: iron ion binding (inferred from electronic annotation from UniProtKB-KW).
GO:0050661; Molecular function: NADP binding (inferred from electronic annotation from InterPro).
GO:0004783; Molecular function: sulfite reductase (NADPH) activity (inferred from electronic annotation from HAMAP).
GO:0019344; Biological process: cysteine biosynthetic process (inferred from electronic annotation from UniProtKB-KW).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
GO:0000103; Biological process: sulfate assimilation (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_01540; -; 1.
PBIL [Tree]
InterPro IPR011786; CysI.
IPR006066; Nir_Si_BS.
IPR006067; Nir_Sir_4Fe4S.
IPR005117; NiRdtase/SiRdtase_haem-b_fer.
Graphical view of domain structure.
Pfam PF01077; NIR_SIR; 1.
PF03460; NIR_SIR_ferr; 2.
Pfam graphical view of domain structure.
PRINTS PR00397; SIROHAEM.
TIGRFAMs TIGR02041; CysI; 1.
PROSITE PS00365; NIR_SIR; 1.
Genome annotation databases
GeneID 1171387; -.
GenomeReviews AE014299_GR; SO_3737.
KEGG son:SO_3737; -.
NMPDR fig|211586.1.peg.3396; -.
TIGR SO_3737; -.
Phylogenomic databases
HOGENOM Q8EB00; -.
Other
ProtoNet Q8EB00.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
4Fe-4S; Amino-acid biosynthesis; Complete proteome; Cysteine biosynthesis; Heme; Iron; Iron-sulfur; Metal-binding; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   565  565     Sulfite reductase [NADPH] hemoprotein beta-component. PRO_0000199909
METAL   429   429        Iron-sulfur (4Fe-4S) (By similarity). 
METAL   435   435        Iron-sulfur (4Fe-4S) (By similarity). 
METAL   474   474        Iron-sulfur (4Fe-4S) (By similarity). 
METAL   478   478        Iron (siroheme axial ligand) (By similarity). 
METAL   478   478        Iron-sulfur (4Fe-4S) (By similarity). 
Sequence information
Length: 565 AA [This is the length of the unprocessed precursor] Molecular weight: 63063 Da [This is the MW of the unprocessed precursor] CRC64: 420F3290EE85066C [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MSEQKLALNE YLKTDSDYLR GTIKEGLDSS VTGSFSDGDQ QLIKFHGFYQ QDDRDLRNER 

        70         80         90        100        110        120 
KEQKLEPLYS FMLRARVPGG VCTPKQWLGV DEIASTLTSS NSIRLTTRQT FQYHGIPKRN 

       130        140        150        160        170        180 
LKTIIQGLDR EALDSIAACG DVNRNVMCNP NPVESKLHAQ AYEVAKKLSD HLLPHTRAYA 

       190        200        210        220        230        240 
EIWLDEEKLL TTEDETVEPV YGKTYLPRKF KMAVAVPPDN DVDVYTNDLG FIAVAENGEL 

       250        260        270        280        290        300 
VGFNLTAGGG MGSTHGEVET FPRLADDFGF IKTEDVMKFA EAVMTVQRDW GNRTNRKRSR 

       310        320        330        340        350        360 
LKYTIVDHGY EKFKAEVEVR AGVKFEPKRD VVIGDRGDRY GWVEGVDGKW HLTLFIESGR 

       370        380        390        400        410        420 
IKDMPGKSLQ TGMREIAKIH KGDFRMTSNQ NMIIAGVAPE DKATIEGLAR KRGLLGQVLT 

       430        440        450        460        470        480 
QTRGHSIACV ALPTCPLAMA EAERYFPEFI DHIDALQAKN GISDQAIVVR MTGCPNGCAR 

       490        500        510        520        530        540 
PFAAEIGLVG KAPGRYNLYL GANFEGTRLN KMYRENIQEA EILAELDALF ARYAIERNAG 

       550        560 
ETFGNFTVRV GVVKAVIDAA KDFHG
Q8EB00 in FASTA format

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