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UniProtKB/Swiss-Prot entry Q8CUL8

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name ODO1_OCEIH
Primary accession number Q8CUL8
Secondary accession numbers None
Integrated into Swiss-Prot on January 24, 2006
Sequence was last modified on March 1, 2003 (Sequence version 1)
Annotations were last modified on    November 4, 2008 (Entry version 35)
Name and origin of the protein
Protein name 2-oxoglutarate dehydrogenase E1 component
Synonyms EC 1.2.4.2
Alpha-ketoglutarate dehydrogenase
Gene name
Name: odhA
OrderedLocusNames: OB1089
From
Oceanobacillus iheyensis [TaxID: 182710] [HAMAP proteome]
Taxonomy Bacteria; Firmicutes; Bacillales; Bacillaceae; Oceanobacillus.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=DSM 14371 / JCM 11309 / KCTC 3954 / HTE831;
DOI=10.1093/nar/gkf526; PubMed=12235376 [NCBI, ExPASy, EBI, Israel, Japan]
Takami H., Takaki Y., Uchiyama I.;
"Genome sequence of Oceanobacillus iheyensis isolated from the Iheya Ridge and its unexpected adaptive capabilities to extreme environments.";
Nucleic Acids Res. 30:3927-3935(2002).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
BA000028; BAC13045.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_692010.1; -.
3D structure databases
ModBase Q8CUL8.
Enzyme and pathway databases
BioCyc OIHE221109:OB1089-MON; -.
Ontologies
GO
GO:0004591; Molecular function: oxoglutarate dehydrogenase (succinyl-transferring) activity (inferred from electronic annotation from HAMAP).
GO:0030976; Molecular function: thiamin pyrophosphate binding (inferred from electronic annotation from HAMAP).
GO:0006096; Biological process: glycolysis (inferred from electronic annotation from HAMAP).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
HAMAP MF_01169; -; 1.
PBIL [Tree]
InterPro IPR011603; 2oxoglutarate_DHase_E1.
IPR001017; DHase_E1.
IPR005475; Transketo_Cen_R.
Graphical view of domain structure.
PANTHER PTHR23152; 2oxoglutarate_DH_E1; 1.
Pfam PF00676; E1_dh; 1.
PF02779; Transket_pyr; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000157; Oxoglu_dh_E1; 1.
TIGRFAMs TIGR00239; 2oxo_dh_E1; 1.
Genome annotation databases
GeneID 1017056; -.
GenomeReviews BA000028_GR; OB1089.
KEGG oih:OB1089; -.
NMPDR fig|221109.1.peg.1090; -.
Phylogenomic databases
HOGENOM Q8CUL8; -.
Genome annotation databases
CMR Q8CUL8; OB1089.
Other
ProtoNet Q8CUL8.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Glycolysis; Oxidoreductase; Thiamine pyrophosphate.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   953  953     2-oxoglutarate dehydrogenase E1 component. PRO_0000162175
Sequence information
Length: 953 AA [This is the length of the unprocessed precursor] Molecular weight: 107266 Da [This is the MW of the unprocessed precursor] CRC64: 78AB32B7CFBE7A6E [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MAENAESAER FWGQFHGQNT GYLEQQFELY KEDPELVESS IRTIFDTHGA PSWLSSTENV 

        70         80         90        100        110        120 
KSVSNASDFD VTKLTSAIRL VEAIRRYGHT DADIYPVGGY KGDRSKMLDL STYNLKEQDL 

       130        140        150        160        170        180 
EKIPASWIWE KQAPGVATAL DVVNQLKKYY TGTITFEYDH VNNDEERKWL FDLIEEGNAR 

       190        200        210        220        230        240 
LDPSDDERKK ILQRLADVEG FEKFLHKTFV GQKRFSIEGL ESMVPMIDHI VQYSNQDSIE 

       250        260        270        280        290        300 
HVMMGMAHRG RLSVLANVLG KPYDKIFSEF NYTKEKELMP SEGSRAINYG WTGDVKYHYG 

       310        320        330        340        350        360 
AEKEVEFGNK GQTRITLAHN PSHLEFVNPV VEGFTRAAQD DRSEKGYPKQ VTNKAVSVLI 

       370        380        390        400        410        420 
HGDAAFIGEG VVAETLNLSG LPGYSTGGTL HIIANNLLGY TTDREDGRST RYASDLAKGF 

       430        440        450        460        470        480 
EIPVIRVNAD DPISCISAIK IAYEYRQKFQ KDFLIDLVGY RRYGHNEMDE PRTTQPSLYQ 

       490        500        510        520        530        540 
QIDDHPSVAS LFGKGMEEKG ILQEGGFEEV KSAVEKKLTD IYKGMTESEI GEPEAKLMPQ 

       550        560        570        580        590        600 
VLTNGLDQFT TAIDLATLKS INEELLERPE GFKGFKKTER ILQRRKDALE EGNKADWGTG 

       610        620        630        640        650        660 
EALAFASILK EGTPIRLTGQ DTERGTFAHR HIVLHDVETG EKYSPLHGLS DVEASFDVRN 

       670        680        690        700        710        720 
SPLSEAGVLG FEYGYSVQSP DTLVIWEAQF GDFANAGQVI FDQFISSARA KWGEKSNMVL 

       730        740        750        760        770        780 
LLPHGYEGQG PEHSSARLER FLQMAAENNW IVANVTSSAQ LFHILRRQAA MRDRDEARPL 

       790        800        810        820        830        840 
VLMTPKSSLI RHPRMGATAE EFTDGGFLAL RDQPGFEANR EKVTRLVVGS GKMMIDIEEA 

       850        860        870        880        890        900 
MDDSDETYDW LQIKRVEQIY PFPKKALEEE IKQLPNLKEI VWVQEEPKNM GAWNFVDDYL 

       910        920        930        940        950 
RELLNEDQKL KVISRPDRSA PAGGIPTVHK TAQNKIIKQA LNQSEGGKSS AGN
Q8CUL8 in FASTA format

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