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UniProtKB/Swiss-Prot entry Q8CPB5

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name TYRA_STAES
Primary accession number Q8CPB5
Secondary accession numbers None
Integrated into Swiss-Prot on April 3, 2007
Sequence was last modified on March 1, 2003 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 37)
Name and origin of the protein
Protein name Prephenate dehydrogenase
Synonyms PDH
EC 1.3.1.12
Gene name
Name: tyrA
OrderedLocusNames: SE_1047
From
Staphylococcus epidermidis (strain ATCC 12228) [TaxID: 176280] [HAMAP proteome]
Taxonomy Bacteria; Firmicutes; Bacillales; Staphylococcus.
Protein existence 4: Predicted;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1046/j.1365-2958.2003.03671.x; PubMed=12950922 [NCBI, ExPASy, EBI, Israel, Japan]
Zhang Y.-Q., Ren S.-X., Li H.-L., Wang Y.-X., Fu G., Yang J., Qin Z.-Q., Miao Y.-G., Wang W.-Y., Chen R.-S., Shen Y., Chen Z., Yuan Z.-H., Zhao G.-P., Qu D., Danchin A., Wen Y.-M.;
"Genome-based analysis of virulence genes in a non-biofilm-forming Staphylococcus epidermidis strain (ATCC 12228).";
Mol. Microbiol. 49:1577-1593(2003).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE015929; AAO04644.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_764602.1; -.
3D structure databases
ModBase Q8CPB5.
Enzyme and pathway databases
BioCyc SEPI176280:SE_1047-MON; -.
Ontologies
GO
GO:0016597; Molecular function: amino acid binding (inferred from electronic annotation from InterPro).
GO:0004665; Molecular function: prephenate dehydrogenase (NADP+) activity (inferred from electronic annotation from InterPro).
GO:0008977; Molecular function: prephenate dehydrogenase activity (inferred from electronic annotation from EC).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
GO:0006571; Biological process: tyrosine biosynthetic process (inferred from electronic annotation from InterPro).
QuickGo view.
Family and domain databases
InterPro IPR002912; ACT_bd.
IPR003099; Prephen_DHase.
Graphical view of domain structure.
PANTHER PTHR21363; Prephen_DH; 1.
Pfam PF01842; ACT; 1.
PF02153; PDH; 1.
Pfam graphical view of domain structure.
PROSITE PS51176; PDH_ADH; 1.
PROSITE graphical view of domain structure (profiles).
Genome annotation databases
GeneID 1056563; -.
GenomeReviews AE015929_GR; SE_1047.
KEGG sep:SE1047; -.
Phylogenomic databases
HOGENOM Q8CPB5; -.
Genome annotation databases
CMR Q8CPB5; SE_1047.
Other
ProtoNet Q8CPB5.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Amino-acid biosynthesis; Aromatic amino acid biosynthesis; Complete proteome; NAD; Oxidoreductase; Tyrosine biosynthesis.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   362  362     Prephenate dehydrogenase. PRO_0000282663
DOMAIN   2   291  290     Prephenate/arogenate dehydrogenase. 
DOMAIN   295   355  61     ACT. 
NP_BIND   3    33  31     NAD (Potential). 
Sequence information
Length: 362 AA [This is the length of the unprocessed precursor] Molecular weight: 40710 Da [This is the MW of the unprocessed precursor] CRC64: BB0D1A12046E0A3B [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MRNILFVGLG LIGGSLASNL KYHYSNFNIL AYDSDYTQLD EALSIGIIDQ KVNDYATAVE 

        70         80         90        100        110        120 
IADIIIFATP VEQTIKYLSE LTNYNTKTHL IVTDTGSTKL TIQSFEKELL KHDIHLISGH 

       130        140        150        160        170        180 
PMAGSHKSGV LNAKKHLFEN AYYILVFNEI ENNEAATYLK KLLKPTLAKF IVTHANEHDF 

       190        200        210        220        230        240 
VTGIVSHVPH IIASILVHLS ANHVKDHSLI EKLAAGGFRD ITRIASSNAQ MWKDITLNNQ 

       250        260        270        280        290        300 
NHILSLLNEI KEQITGIENL IREQNSNSIY DFFVKAKDYR DQLPVKQHGA ISTAYDLYVD 

       310        320        330        340        350        360 
IPDKPGMISQ ITNIISSHNI SIINLKILEV REDIYGALQI SFKSPEDREN AIKALANFDT 


YY
Q8CPB5 in FASTA format

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