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UniProtKB/Swiss-Prot entry Q8BTZ7


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name GMPPB_MOUSE
Primary accession number Q8BTZ7
Secondary accession numbers None
Integrated into Swiss-Prot on October 23, 2007
Sequence was last modified on March 1, 2003 (Sequence version 1)
Annotations were last modified on    December 16, 2008 (Entry version 46)
Name and origin of the protein
Protein name Mannose-1-phosphate guanyltransferase beta
Synonyms EC 2.7.7.13
GTP-mannose-1-phosphate guanylyltransferase beta
GDP-mannose pyrophosphorylase B
Gene name
Name: Gmppb
From
Mus musculus (Mouse) [TaxID: 10090] 
Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus.
Protein existence 2: Evidence at transcript level;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
STRAIN=C57BL/6J, and NOD;
TISSUE=Inner ear, and Thymus;
DOI=10.1126/science.1112014; PubMed=16141072 [NCBI, ExPASy, EBI, Israel, Japan]
Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J., Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
"The transcriptional landscape of the mammalian genome.";
Science 309:1559-1563(2005).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
TISSUE=Pituitary;
DOI=10.1101/gr.2596504; PubMed=15489334 [NCBI, ExPASy, EBI, Israel, Japan]
The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AK088295; BAC40266.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AK148125; BAE28361.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AK158470; BAE34527.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
BC061207; AAH61207.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_808578.1; -.
UniGene Mm.22554
3D structure databases
ModBase Q8BTZ7.
Protein-protein interaction databases
IntAct Q8BTZ7; 1.
PTM databases
PhosphoSite Q8BTZ7; -.
2D gel databases
REPRODUCTION-2DPAGE Q8BTZ7; -.
Organism-specific databases
MGI MGI:2660880; Gmppb.
Gene expression databases
CleanEx MM_GMPPB; -.
Ontologies
GO
GO:0004475; Molecular function: mannose-1-phosphate guanylyltransferase activity (inferred from electronic annotation from EC).
GO:0009058; Biological process: biosynthetic process (inferred from electronic annotation from InterPro).
QuickGo view.
Family and domain databases
InterPro IPR001451; Hexapep_transf.
IPR005835; NTP_transferase.
Graphical view of domain structure.
Pfam PF00132; Hexapep; 3.
PF00483; NTP_transferase; 1.
Pfam graphical view of domain structure.
PROSITE PS00101; HEXAPEP_TRANSFERASES; 1.
Proteomics databases
PRIDE Q8BTZ7; -.
Genome annotation databases
Ensembl ENSMUSG00000070284; Mus musculus. [Contig view]
GeneID 331026; -.
KEGG mmu:331026; -.
Phylogenomic databases
HOGENOM Q8BTZ7; -.
HOVERGEN Q8BTZ7; -.
Other
NextBio 399690; -.
SOURCE Gmppb; Mus musculus.
ProtoNet Q8BTZ7.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Nucleotidyltransferase; Transferase.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   360  360     Mannose-1-phosphate guanyltransferase beta. PRO_0000307163
Sequence information
Length: 360 AA [This is the length of the unprocessed precursor] Molecular weight: 39917 Da [This is the MW of the unprocessed precursor] CRC64: 2AF911A12C801A1D [This is a checksum on the sequence]
        10         20         30         40         50         60 
MKALILVGGY GTRLRPLTLS TPKPLVDFCN KPILLHQVEA LAAAGVDHVI LAVSYMSQML 

        70         80         90        100        110        120 
EKEMKAQEQR LGIRISMSHE EEPLGTAGPL ALARDLLSET ADPFFVLNSD VICDFPFQAM 

       130        140        150        160        170        180 
VQFHRHHGQE GSILVTKVEE PSKYGVVVCE ADTGRIHRFV EKPQVFVSNK INAGMYILSP 

       190        200        210        220        230        240 
AVLQRIQLKP TSIEKEIFPV MAKEGQLYAM ELQGFWMDIG QPKDFLTGMC LFLQSLRQKH 

       250        260        270        280        290        300 
PERLYSGPGI VGNVLVDPSA RIGQNCSIGP NVSLGPGVVV EDGVCIRRCT VLRDAHIRSH 

       310        320        330        340        350        360 
SWLESCIVGW RCRVGQWVRM ENVTVLGEDV IVNDELYLNG ASVLPHKSIG ESVPEPRIIM 

Q8BTZ7 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
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BLAST logo BLAST submission on ExPASy/SIB
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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
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