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UniProtKB/Swiss-Prot entry Q8A6N4

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name PURA_BACTN
Primary accession number Q8A6N4
Secondary accession numbers None
Integrated into Swiss-Prot on April 13, 2004
Sequence was last modified on June 1, 2003 (Sequence version 1)
Annotations were last modified on    October 14, 2008 (Entry version 42)
Name and origin of the protein
Protein name Adenylosuccinate synthetase
Synonyms EC 6.3.4.4
IMP--aspartate ligase
AdSS
AMPSase
Gene name
Name: purA
OrderedLocusNames: BT_1843
From
Bacteroides thetaiotaomicron [TaxID: 818] [HAMAP proteome]
Taxonomy Bacteria; Bacteroidetes; Bacteroidia; Bacteroidales; Bacteroidaceae; Bacteroides.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482;
DOI=10.1126/science.1080029; PubMed=12663928 [NCBI, ExPASy, EBI, Israel, Japan]
Xu J., Bjursell M.K., Himrod J., Deng S., Carmichael L.K., Chiang H.C., Hooper L.V., Gordon J.I.;
"A genomic view of the human-Bacteroides thetaiotaomicron symbiosis.";
Science 299:2074-2076(2003).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE015928; AAO76950.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_810756.1; -.
3D structure databases
HSSP P12283; 1ADE. [HSSP ENTRY / PDB]
ModBase Q8A6N4.
Enzyme and pathway databases
BioCyc BTHE226186:BT_1843-MON; -.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0004019; Molecular function: adenylosuccinate synthase activity (inferred from electronic annotation from HAMAP).
GO:0005525; Molecular function: GTP binding (inferred from electronic annotation from HAMAP).
GO:0000287; Molecular function: magnesium ion binding (inferred from electronic annotation from HAMAP).
GO:0006164; Biological process: purine nucleotide biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00011; -; 1.
PBIL [Tree]
InterPro IPR001114; AdlSucc_Synth.
Graphical view of domain structure.
PANTHER PTHR11846; Asucc_synthtase; 1.
Pfam PF00709; Adenylsucc_synt; 1.
Pfam graphical view of domain structure.
ProDom PD001188; Asucc_synthtase; 1.
[Domain structure / List of seq. sharing at least 1 domain]
SMART SM00788; Adenylsucc_synt; 1.
SMART graphical view of domain structure.
TIGRFAMs TIGR00184; purA; 1.
PROSITE PS01266; ADENYLOSUCCIN_SYN_1; 1.
PS00513; ADENYLOSUCCIN_SYN_2; 1.
Genome annotation databases
GeneID 1075166; -.
GenomeReviews AE015928_GR; BT_1843.
KEGG bth:BT_1843; -.
NMPDR fig|226186.1.peg.1843; -.
Phylogenomic databases
HOGENOM Q8A6N4; -.
Genome annotation databases
CMR Q8A6N4; BT_1843.
Other
ProtoNet Q8A6N4.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Cytoplasm; GTP-binding; Ligase; Magnesium; Metal-binding; Nucleotide-binding; Purine biosynthesis.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   423  423     Adenylosuccinate synthetase. PRO_0000095147
NP_BIND   12    18  7     GTP (Potential). 
ACT_SITE   140   140        By similarity. 
ACT_SITE   147   147        By similarity. 
METAL   13    13        Magnesium (By similarity). 
METAL   40    40        Magnesium; via carbonyl oxygen (By similarity). 
Sequence information
Length: 423 AA [This is the length of the unprocessed precursor] Molecular weight: 46789 Da [This is the MW of the unprocessed precursor] CRC64: 1569243D88FB2FDB [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MKVDVLLGLQ WGDEGKGKVV DVLTPKYDVV ARFQGGPNAG HTLEFEGQKY VLRSIPSGIF 

        70         80         90        100        110        120 
QGDKVNIIGN GVVLDPALFK AEAEALEASG HPLKERLHIS KKAHLILPTH RILDAAYEAA 

       130        140        150        160        170        180 
KGDAKVGTTG KGIGPTYTDK VSRNGVRVGD ILHNFEQKYG AAKARHEQIL KSLNYEYDLT 

       190        200        210        220        230        240 
ELEKAWMEGI EYLKQFHFVD SEHEVNNYLK DGKSVLCEGA QGTMLDIDFG SYPFVTSSNT 

       250        260        270        280        290        300 
VCAGACTGLG VAPNRIGEVF GIFKAYCTRV GAGPFPTELF DETGDKMCTL GHEFGSVTGR 

       310        320        330        340        350        360 
KRRCGWIDLV ALKYSVMING VTKLIMMKSD VLDTFDTIKA CVAYKVDGEE IDYFPYDITE 

       370        380        390        400        410        420 
GVEPVYAELP GWKTDMTKMQ SEDEFPEEFN AYLTFLEEQL GVEIKIVSVG PDRAQTIERY 


TEE
Q8A6N4 in FASTA format

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