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UniProtKB/Swiss-Prot entry Q8A1E8

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name PROA_BACTN
Primary accession number Q8A1E8
Secondary accession numbers None
Integrated into Swiss-Prot on December 15, 2003
Sequence was last modified on June 1, 2003 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 49)
Name and origin of the protein
Protein name Gamma-glutamyl phosphate reductase
Synonyms GPR
EC 1.2.1.41
Glutamate-5-semialdehyde dehydrogenase
Glutamyl-gamma-semialdehyde dehydrogenase
GSA dehydrogenase
Gene name
Name: proA
OrderedLocusNames: BT_3718
From
Bacteroides thetaiotaomicron [TaxID: 818] [HAMAP proteome]
Taxonomy Bacteria; Bacteroidetes; Bacteroidia; Bacteroidales; Bacteroidaceae; Bacteroides.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482;
DOI=10.1126/science.1080029; PubMed=12663928 [NCBI, ExPASy, EBI, Israel, Japan]
Xu J., Bjursell M.K., Himrod J., Deng S., Carmichael L.K., Chiang H.C., Hooper L.V., Gordon J.I.;
"A genomic view of the human-Bacteroides thetaiotaomicron symbiosis.";
Science 299:2074-2076(2003).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE015928; AAO78823.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_812629.1; -.
3D structure databases
HSSP Q9WYC9; 1O20. [HSSP ENTRY / PDB]
ModBase Q8A1E8.
Enzyme and pathway databases
BioCyc BTHE226186:BT_3718-MON; -.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0004350; Molecular function: glutamate-5-semialdehyde dehydrogenase activity (inferred from electronic annotation from HAMAP).
GO:0050661; Molecular function: NADP binding (inferred from electronic annotation from InterPro).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
GO:0006561; Biological process: proline biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00412; -; 1.
PBIL [Tree]
InterPro IPR016163; Ald_DHase_C.
IPR016162; Ald_DHase_N.
IPR000965; Gglut_pp_reduct.
IPR012134; Glu-5-SA_DHase.
Graphical view of domain structure.
Gene3D G3DSA:3.40.309.10; Aldehyde_dehydrogenase_C; 1.
G3DSA:3.40.605.10; Aldehyde_dehydrogenase_N; 1.
PANTHER PTHR11063:SF1; GSA_DH; 1.
PIRSF PIRSF000151; GPR; 1.
TIGRFAMs TIGR00407; proA; 1.
PROSITE PS01223; PROA; 1.
Genome annotation databases
GeneID 1075939; -.
GenomeReviews AE015928_GR; BT_3718.
KEGG bth:BT_3718; -.
NMPDR fig|226186.1.peg.3716; -.
Phylogenomic databases
HOGENOM Q8A1E8; -.
Genome annotation databases
CMR Q8A1E8; BT_3718.
Other
ProtoNet Q8A1E8.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Amino-acid biosynthesis; Complete proteome; Cytoplasm; NADP; Oxidoreductase; Proline biosynthesis.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   417  417     Gamma-glutamyl phosphate reductase. PRO_0000189697
Sequence information
Length: 417 AA [This is the length of the unprocessed precursor] Molecular weight: 45645 Da [This is the MW of the unprocessed precursor] CRC64: 2B2D91E6B4D7A8C5 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MTTNLNGTFA AVQAASRELA LLSDDTINQI LNAVADATIA ETSFILSENE KDLARMDKSN 

        70         80         90        100        110        120 
PKYDRLKLTE ERLKGIAADT RNVATLPSPL GRILKETSRP NGMKLTKVSV PFGVIGIIYE 

       130        140        150        160        170        180 
ARPNVSFDVF SLCLKSGNAC ILKGGSDADD SNRAIISVIH KVLEKFHVNP HIVELLPADR 

       190        200        210        220        230        240 
EATAALLNAT GYVDLIIPRG SSNLINFVRE NARIPVIETG AGICHTYFDE FGDTRKGADI 

       250        260        270        280        290        300 
IHNAKTRRVS VCNALDCTII HEKRLGDLPA LCDQLKESKV TIYADTQAYQ ALEGYYPAEL 

       310        320        330        340        350        360 
LQPATPESFG TEFLDYKMAV KTVKSFEDAL GHIQENSSRH SECIVTENKE RATLFTKIVD 

       370        380        390        400        410 
AACVYTNVST AFTDGAQFGL GAEIGISTQK LHARGPMGLE EITSYKWVIE GDGQTRW
Q8A1E8 in FASTA format

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