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UniProtKB/Swiss-Prot entry Q83FD0


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name AROE_COXBU
Primary accession number Q83FD0
Secondary accession numbers None
Integrated into Swiss-Prot on January 15, 2008
Sequence was last modified on June 1, 2003 (Sequence version 1)
Annotations were last modified on    November 4, 2008 (Entry version 39)
Name and origin of the protein
Protein name Shikimate dehydrogenase
Synonym EC 1.1.1.25
Gene name
Name: aroE
OrderedLocusNames: CBU_0010
From
Coxiella burnetii [TaxID: 777] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Legionellales; Coxiellaceae; Coxiella.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Nine Mile phase I / RSA 493;
DOI=10.1073/pnas.0931379100; PubMed=12704232 [NCBI, ExPASy, EBI, Israel, Japan]
Seshadri R., Paulsen I.T., Eisen J.A., Read T.D., Nelson K.E., Nelson W.C., Ward N.L., Tettelin H., Davidsen T.M., Beanan M.J., DeBoy R.T., Daugherty S.C., Brinkac L.M., Madupu R., Dodson R.J., Khouri H.M., Lee K.H., Carty H.A., Scanlan D., Heinzen R.A., Thompson H.A., Samuel J.E., Fraser C.M., Heidelberg J.F.;
"Complete genome sequence of the Q-fever pathogen, Coxiella burnetii.";
Proc. Natl. Acad. Sci. U.S.A. 100:5455-5460(2003).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE016828; AAO89580.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_819066.1; -.
3D structure databases
HSSP P15770; 1NYT. [HSSP ENTRY / PDB]
ModBase Q83FD0.
Enzyme and pathway databases
BioCyc CBUR227377:CBU_0010-MON; -.
Ontologies
GO
GO:0004764; Molecular function: shikimate 5-dehydrogenase activity (inferred from electronic annotation from HAMAP).
GO:0009073; Biological process: aromatic amino acid family biosynthetic process (inferred from electronic annotation from HAMAP).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
HAMAP MF_00222; -; 1.
PBIL [Tree]
InterPro IPR016040; NAD(P)-bd.
IPR011342; Quinate/shikimate_5-DHase.
IPR013708; Shikimate_DHase-bd_N.
IPR006151; Shikm_DHase/Glu-tRNA_Rdtase.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
Pfam PF01488; Shikimate_DH; 1.
PF08501; Shikimate_dh_N; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR00507; aroE; 1.
BLOCKS Q83FD0.
ProtoNet Q83FD0.
Genome annotation databases
GeneID 1207872; -.
GenomeReviews AE016828_GR; CBU_0010.
KEGG cbu:CBU_0010; -.
NMPDR fig|227377.1.peg.10; -.
TIGR CBU_0010; -.
Phylogenomic databases
HOGENOM Q83FD0; -.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Amino-acid biosynthesis; Aromatic amino acid biosynthesis; Complete proteome; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   272  272     Shikimate dehydrogenase. PRO_1000021279
NP_BIND   127   131  5     NADP (By similarity). 
ACT_SITE   65    65        Proton acceptor (Potential). 
Sequence information
Length: 272 AA [This is the length of the unprocessed precursor] Molecular weight: 29794 Da [This is the MW of the unprocessed precursor] CRC64: F1DA0DAB51DADB73 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MDKYAVIGNP VEHSLSPVIF QAFEKQTNHS FDYLKIKAPV NGFAAAVKKF HDEGGKGANI 

        70         80         90        100        110        120 
TLPFKEEAYQ LADKRSQEAN EAHVASALQF REDGTIYAVN YDGLGLVQDL TRNHNITLTQ 

       130        140        150        160        170        180 
KSILIVGAGG ATRGILGPLL NAAPEKIVIV NRTPSKAHAL AKIFHLRGEI QGGGFDELEP 

       190        200        210        220        230        240 
MRYDVIIHAT SLGHQGKFPP LPDGLIGSQS CCYDLSYGKI ASPFLQWAKD QGAKYNFDGL 

       250        260        270 
GMLVEHNAAV FYLWFGIYPD TNPVIEMLQA HL 

Q83FD0 in FASTA format

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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
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