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UniProtKB/Swiss-Prot entry Q81IU1

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name DDLB_BACCR
Primary accession number Q81IU1
Secondary accession numbers None
Integrated into Swiss-Prot on December 15, 2003
Sequence was last modified on June 1, 2003 (Sequence version 1)
Annotations were last modified on    November 4, 2008 (Entry version 45)
Name and origin of the protein
Protein name D-alanine--D-alanine ligase B
Synonyms EC 6.3.2.4
D-alanylalanine synthetaseB
D-Ala-D-Ala ligase B
Gene name
Name: ddlB
OrderedLocusNames: BC_0257
From
Bacillus cereus (strain ATCC 14579 / DSM 31) [TaxID: 226900] [HAMAP proteome]
Taxonomy Bacteria; Firmicutes; Bacillales; Bacillaceae; Bacillus; Bacillus cereus group.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1038/nature01582; PubMed=12721630 [NCBI, ExPASy, EBI, Israel, Japan]
Ivanova N., Sorokin A., Anderson I., Galleron N., Candelon B., Kapatral V., Bhattacharyya A., Reznik G., Mikhailova N., Lapidus A., Chu L., Mazur M., Goltsman E., Larsen N., D'Souza M., Walunas T., Grechkin Y., Pusch G., Haselkorn R., Fonstein M., Ehrlich S.D., Overbeek R., Kyrpides N.C.;
"Genome sequence of Bacillus cereus and comparative analysis with Bacillus anthracis.";
Nature 423:87-91(2003).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE016877; AAP07326.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_830125.1; -.
3D structure databases
HSSP P07862; 1IOW. [HSSP ENTRY / PDB]
ModBase Q81IU1.
Enzyme and pathway databases
BioCyc BCER226900:BC_0257-MON; -.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0008716; Molecular function: D-alanine-D-alanine ligase activity (inferred from electronic annotation from HAMAP).
GO:0000287; Molecular function: magnesium ion binding (inferred from electronic annotation from UniProtKB-KW).
GO:0030145; Molecular function: manganese ion binding (inferred from electronic annotation from UniProtKB-KW).
GO:0009252; Biological process: peptidoglycan biosynthetic process (inferred from electronic annotation from HAMAP).
GO:0008360; Biological process: regulation of cell shape (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
HAMAP MF_00047; -; 1.
PBIL [Tree]
InterPro IPR011761; ATP-grasp.
IPR013816; ATP_grasp_subdomain_2.
IPR000291; D-Ala_lig_Van_CS.
IPR005905; D_ala_D_ala.
IPR011095; Dala_Dala_lig_C.
IPR011127; Dala_Dala_lig_N.
IPR013817; Pre-ATP_grasp.
Graphical view of domain structure.
Gene3D G3DSA:3.30.470.20; ATP_grasp_subdomain_2; 1.
G3DSA:3.40.50.20; Pre-ATP_grasp; 1.
Pfam PF07478; Dala_Dala_lig_C; 1.
PF01820; Dala_Dala_lig_N; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR01205; D_ala_D_alaTIGR; 1.
PROSITE PS50975; ATP_GRASP; 1.
PS00843; DALA_DALA_LIGASE_1; 1.
PS00844; DALA_DALA_LIGASE_2; 1.
PROSITE graphical view of domain structure (profiles).
BLOCKS Q81IU1.
ProtoNet Q81IU1.
Genome annotation databases
GeneID 1202610; -.
GenomeReviews AE016877_GR; BC_0257.
KEGG bce:BC0257; -.
Phylogenomic databases
HOGENOM Q81IU1; -.
Genome annotation databases
CMR Q81IU1; BC_0257.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
ATP-binding; Cell shape; Cell wall biogenesis/degradation; Complete proteome; Cytoplasm; Ligase; Magnesium; Manganese; Metal-binding; Nucleotide-binding; Peptidoglycan synthesis.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   361  361     D-alanine--D-alanine ligase B. PRO_0000177783
DOMAIN   140   345  206     ATP-grasp. 
NP_BIND   173   228  56     ATP (By similarity). 
METAL   299   299        Magnesium or manganese 1 (By similarity). 
METAL   312   312        Magnesium or manganese 1 (By similarity). 
METAL   312   312        Magnesium or manganese 2 (By similarity). 
METAL   314   314        Magnesium or manganese 2 (By similarity). 
Sequence information
Length: 361 AA [This is the length of the unprocessed precursor] Molecular weight: 40073 Da [This is the MW of the unprocessed precursor] CRC64: 885D9E7C8FDC9214 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MTKIKLGLLY GGKSAEHQVS LQTALAAIKA LNQDKFEIHP IYITEQGQWV RGERIEGEVT 

        70         80         90        100        110        120 
DVEALKMSGA ENAISPLSLS TEIIPSAASE ENAIDVIFPL LHGPNGEDGT VQGLLELMNI 

       130        140        150        160        170        180 
PYVGNGVLAS SAGMDKVVMK NIFAEAGLKQ AKYASFIRSA WEKNREEAYS KVEDKLGYPC 

       190        200        210        220        230        240 
FVKPANLGSS VGINKCKNRE ELEDAFVEAF QFDRKIIVEE NIVGREVEVG VLGNDEPKCS 

       250        260        270        280        290        300 
VVGEIVPKKD FYDYKSKYID GDTALIIPAE MTEEESNVIK RDAIIAFQSL DGAGLTRADF 

       310        320        330        340        350        360 
FLTKDGEVYI NEVNTMPGFT PFSMFPLLWQ HTGLPYPELI EELIRLAIER HEEKQKIKYT 


I
Q81IU1 in FASTA format

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