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UniProtKB/Swiss-Prot entry Q639D2


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name ARSC_BACCZ
Primary accession number Q639D2
Secondary accession numbers None
Integrated into Swiss-Prot on January 10, 2006
Sequence was last modified on October 25, 2004 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 28)
Name and origin of the protein
Protein name Protein arsC
Synonyms Arsenate reductase
EC 1.20.4.-
Arsenical pump modifier
Low molecular weight protein-tyrosine-phosphatase
EC 3.1.3.48
Gene name
Name: arsC
OrderedLocusNames: BCE33L2898
From
Bacillus cereus (strain ZK / E33L) [TaxID: 288681] [HAMAP proteome]
Taxonomy Bacteria; Firmicutes; Bacillales; Bacillaceae; Bacillus; Bacillus cereus group.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1128/JB.188.9.3382-3390.2006; PubMed=16621833 [NCBI, ExPASy, EBI, Israel, Japan]
Han C.S., Xie G., Challacombe J.F., Altherr M.R., Bhotika S.S., Bruce D., Campbell C.S., Campbell M.L., Chen J., Chertkov O., Cleland C., Dimitrijevic M., Doggett N.A., Fawcett J.J., Glavina T., Goodwin L.A., Hill K.K., Hitchcock P., Jackson P.J., Keim P., Kewalramani A.R., Longmire J., Lucas S., Malfatti S., McMurry K., Meincke L.J., Misra M., Moseman B.L., Mundt M., Munk A.C., Okinaka R.T., Parson-Quintana B., Reilly L.P., Richardson P., Robinson D.L., Rubin E., Saunders E., Tapia R., Tesmer J.G., Thayer N., Thompson L.S., Tice H., Ticknor L.O., Wills P.L., Brettin T.S., Gilna P.;
"Pathogenomic sequence analysis of Bacillus cereus and Bacillus thuringiensis isolates closely related to Bacillus anthracis.";
J. Bacteriol. 188:3382-3390(2006).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CP000001; AAU17365.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_084485.1; -.
3D structure databases
SMR Q639D2; 5-134.
ModBase Q639D2.
Enzyme and pathway databases
BioCyc BCER288681:BCE33L2898-MON; -.
Ontologies
GO
GO:0030612; Molecular function: arsenate reductase (thioredoxin) activity (inferred from electronic annotation from HAMAP).
GO:0004725; Molecular function: protein tyrosine phosphatase activity (inferred from electronic annotation from HAMAP).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
GO:0006470; Biological process: protein amino acid dephosphorylation (inferred from electronic annotation from InterPro).
GO:0046685; Biological process: response to arsenic (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
HAMAP MF_01624; -; 1.
PBIL [Tree]
InterPro IPR014064; Arsenate_reductase_StaphA.
IPR000106; Tyr_Pase_low_mol_wt.
Graphical view of domain structure.
PANTHER PTHR11717; Low_mwt_PTPase; 1.
Pfam PF01451; LMWPc; 1.
Pfam graphical view of domain structure.
SMART SM00226; LMWPc; 1.
SMART graphical view of domain structure.
TIGRFAMs TIGR02691; arsC_pI258_fam; 1.
Genome annotation databases
GeneID 3024191; -.
GenomeReviews CP000001_GR; BCE33L2898.
KEGG bcz:BCZK2898; -.
Phylogenomic databases
HOGENOM Q639D2; -.
Genome annotation databases
CMR Q639D2; BCE33L2898.
Other
ProtoNet Q639D2.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Arsenical resistance; Complete proteome; Hydrolase; Oxidoreductase; Redox-active center.
Features
SEVIEWER logo Feature table viewer
KeyFrom  To Length Description FTId
CHAIN   1   134  134     Protein arsC. PRO_0000162515
ACT_SITE   11    11        Nucleophile; for reductase activity and phosphatase activity (By similarity). 
ACT_SITE   83    83        Nucleophile; for reductase activity (By similarity). 
ACT_SITE   90    90        Nucleophile; for reductase activity (By similarity). 
DISULFID   11    83        Redox-active; alternate (By similarity). 
DISULFID   83    90        Redox-active; alternate (By similarity). 
Sequence information
Length: 134 AA [This is the length of the unprocessed precursor] Molecular weight: 15078 Da [This is the MW of the unprocessed precursor] CRC64: 715F16EC0EA10F9D [This is a checksum on the sequence]
        10         20         30         40         50         60 
MENKKTIYFL CTGNSCRSQM AEAWGKQYLG DKWNVYSAGI EVHGVNPNAI KAMNEVNIDI 

        70         80         90        100        110        120 
TNQTSDIIDA NILNRADLVV TLCSHADSVC PSTPPDVNRV HWGFDDPAGK EWSEFQRVRD 

       130 
EIGERIKRFS ETGE 

Q639D2 in FASTA format

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