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UniProtKB/Swiss-Prot entry Q5PHC0

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name ASTD_SALPA
Primary accession number Q5PHC0
Secondary accession numbers None
Integrated into Swiss-Prot on November 28, 2006
Sequence was last modified on January 4, 2005 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 31)
Name and origin of the protein
Protein name N-succinylglutamate 5-semialdehyde dehydrogenase
Synonyms EC 1.2.1.71
Succinylglutamic semialdehyde dehydrogenase
SGSD
Gene name
Name: astD
OrderedLocusNames: SPA1539
From
Salmonella paratyphi A [TaxID: 54388] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Salmonella.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 9150 / SARB42;
DOI=10.1038/ng1470; PubMed=15531882 [NCBI, ExPASy, EBI, Israel, Japan]
McClelland M., Sanderson K.E., Clifton S.W., Latreille P., Porwollik S., Sabo A., Meyer R., Bieri T., Ozersky P., McLellan M., Harkins C.R., Wang C., Nguyen C., Berghoff A., Elliott G., Kohlberg S., Strong C., Du F., Carter J., Kremizki C., Layman D., Leonard S., Sun H., Fulton L., Nash W., Miner T., Minx P., Delehaunty K., Fronick C., Magrini V., Nhan M., Warren W., Florea L., Spieth J., Wilson R.K.;
"Comparison of genome degradation in Paratyphi A and Typhi, human-restricted serovars of Salmonella enterica that cause typhoid.";
Nat. Genet. 36:1268-1274(2004).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CP000026; AAV77472.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_150784.1; -.
3D structure databases
ModBase Q5PHC0.
Enzyme and pathway databases
BioCyc SENT295319:SPA1539-MON; -.
Ontologies
GO
GO:0043824; Molecular function: succinylglutamate-semialdehyde dehydrogenase activity (inferred from electronic annotation from InterPro).
GO:0019544; Biological process: arginine catabolic process to glutamate (inferred from electronic annotation from HAMAP).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
HAMAP MF_01174; -; 1.
PBIL [Tree]
InterPro IPR016160; Ald_DHase_CS.
IPR016162; Ald_DHase_N.
IPR015590; Aldehyde_DHase.
IPR017649; SuccinylGlu_semiald_DH_AstD.
Graphical view of domain structure.
Gene3D G3DSA:3.40.605.10; Aldehyde_dehydrogenase_N; 1.
PANTHER PTHR11699; Aldehyde_dehyd; 1.
Pfam PF00171; Aldedh; 1.
Pfam graphical view of domain structure.
PROSITE PS00070; ALDEHYDE_DEHYDR_CYS; 1.
PS00687; ALDEHYDE_DEHYDR_GLU; 1.
Genome annotation databases
GeneID 3176125; -.
GenomeReviews CP000026_GR; SPA1539.
KEGG spt:SPA1539; -.
NMPDR fig|295319.3.peg.1459; -.
Phylogenomic databases
HOGENOM Q5PHC0; -.
Genome annotation databases
CMR Q5PHC0; SPA1539.
Other
ProtoNet Q5PHC0.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Arginine metabolism; Complete proteome; NAD; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   492  492     N-succinylglutamate 5-semialdehyde dehydrogenase. PRO_0000262420
NP_BIND   220   225  6     NAD (By similarity). 
ACT_SITE   243   243        By similarity. 
ACT_SITE   277   277        By similarity. 
Sequence information
Length: 492 AA [This is the length of the unprocessed precursor] Molecular weight: 53088 Da [This is the MW of the unprocessed precursor] CRC64: 096438045D3F8695 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MTLWINGDWI TGQGERRRKT NPVSAEILWQ GNDANAAQVA EACQAARAAF PRWARQPFTA 

        70         80         90        100        110        120 
RQAIVQKFAA LLEAHKADLT EVIARETGKP RWEAATEVTA MINKIAISIK AYHARTGEQK 

       130        140        150        160        170        180 
SELVDGAATL RHRPHGVLAV FGPYNFPGHL PNGHIVSALL AGNTLIFKPS ELTPWTGETV 

       190        200        210        220        230        240 
IKLWERAGLP AGVLNLVQGG RETGQALSSL DDLDGLLFTG SASTGYQLHR QLSGQPEKIL 

       250        260        270        280        290        300 
ALEMGGNNPL IIEDVANIDA AVHLTLQSAF ITAGQRCTCA RRLLVKQGAQ GDAFLARLVD 

       310        320        330        340        350        360 
VAGRLQPGRW DDDPQSFIGG LISAQAAQHV MEAWRQREAL GGRTLLASRK VKEGTSLLTP 

       370        380        390        400        410        420 
GIIELTGVAD VPDEEVFGPL LNVWRYAHFD EAIRLANNTR FGLSCGLVST DRAQFEQLLL 

       430        440        450        460        470        480 
EARAGIVNWN KPLTGAASTA PFGGVGASGN HRPSAWYAAD YCAWPMASLE SPELTLPATL 

       490 
SPGLDFSRRE AV
Q5PHC0 in FASTA format

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