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[1]
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NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440;
PubMed=8688087 [NCBI, ExPASy, EBI, Israel, Japan]
Bult C.J.,
White O.,
Olsen G.J.,
Zhou L.,
Fleischmann R.D.,
Sutton G.G.,
Blake J.A.,
FitzGerald L.M.,
Clayton R.A.,
Gocayne J.D.,
Kerlavage A.R.,
Dougherty B.A.,
Tomb J.-F.,
Adams M.D.,
Reich C.I.,
Overbeek R.,
Kirkness E.F.,
Weinstock K.G.,
Merrick J.M., ![]()
Glodek A.,
Scott J.L.,
Geoghagen N.S.M.,
Weidman J.F.,
Fuhrmann J.L.,
Nguyen D.,
Utterback T.R.,
Kelley J.M.,
Peterson J.D.,
Sadow P.W.,
Hanna M.C.,
Cotton M.D.,
Roberts K.M.,
Hurst M.A.,
Kaine B.P.,
Borodovsky M.,
Klenk H.-P.,
Fraser C.M.,
Smith H.O.,
Woese C.R.,
Venter J.C.;
"Complete genome sequence of the methanogenic archaeon, Methanococcus jannaschii.";
Science 273:1058-1073(1996).
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[2]
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CHARACTERIZATION.
PubMed=9555910 [NCBI, ExPASy, EBI, Israel, Japan]
Ishino Y.,
Komori K.,
Cann I.K.O.,
Koga Y.;
"A novel DNA polymerase family found in Archaea.";
J. Bacteriol. 180:2232-2236(1998).
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- FUNCTION: Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase.
- CATALYTIC ACTIVITY: Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
- CATALYTIC ACTIVITY: Degradation of single-stranded DNA. It acts progressively in a 3'- to 5'-direction, releasing nucleoside 5'-phosphates.
- SUBUNIT: Heterodimer of a large subunit and a small subunit.
- SIMILARITY: Belongs to the archaeal DNA polymerase II family.
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Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms.
Distributed under the Creative Commons Attribution-NoDerivs License.
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| Length: 1139 AA [This is the length of the unprocessed precursor] |
Molecular weight: 129402 Da [This is the MW of the unprocessed precursor] |
CRC64: 3B7968A013AAC45A [This is a checksum on the sequence] |
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10 20 30 40 50 60
MIVMVHVACS ENMKKYFENI VDEVKKIYRI AEECRKKGFD PTDEVEIPLA ADMADRVEGL
70 80 90 100 110 120
VGPKGVAERI RELVKELGKE PAALEIAKEI VEGKFGNFDK EKKAEQAVRT ALAVLTEGIV
130 140 150 160 170 180
AAPLEGIADV KIKKNPDGTE YLAIYYAGPI RSAGGTAQAL SVLVGDFVRK AMGLDRYKPT
190 200 210 220 230 240
EDEIERYVEE VELYQSEVGS FQYNPTADEI RTAIRNIPIE ITGEATDDVE VSGHRDLPRV
250 260 270 280 290 300
ETNQLRGGAL LVLVEGVLLK APKILRHVDK LGIEGWDWLK DLMSKKEEKE EEKDEKVDDE
310 320 330 340 350 360
EIDEEEEEIS GYWRDVKIEA NKKFISEVIA GRPVFAHPSK VGGFRLRYGR SRNTGFATQG
370 380 390 400 410 420
FHPALMYLVD EFMAVGTQLK TERPGKATCV VPVDSIEPPI VKLKNGDVIR VDTIEKAMDV
430 440 450 460 470 480
RNRVEEILFL GDVLVNYGDF LENNHPLLPS CWCEEWYEKI LIANNIEYDK DFIKNPKPEE
490 500 510 520 530 540
AVKFALETKT PLHPRFTYHW HDVSKEDIIL LRNWLLKGKE DSLEGKKVWI VDLEIEEDKK
550 560 570 580 590 600
AKRILELIGC CHLVRNKKVI IEEYYPLLYS LGFDVENKKD LVENIEKILE SAKNSMHLIN
610 620 630 640 650 660
LLAPFEVRRN TYVYVGARMG RPEKAAPRKM KPPVNGLFPI GNAGGQVRLI NKAVEENNTD
670 680 690 700 710 720
DVDVSYTRCP NCGKISLYRV CPFCGTKVEL DNFGRIKAPL KDYWYAALKR LGINKPGDVK
730 740 750 760 770 780
CIKGMTSKQK IVEPLEKAIL RAINEVYVFK DGTTRFDCTD VPVTHFKPNE INVTVEKLRE
790 800 810 820 830 840
LGYDKDIYGN ELVDGEQVVE LKPQDVIIPE SCAEYFVKVA NFIDDLLEKF YKVERFYNVK
850 860 870 880 890 900
KKEDLIGHLV IGMAPHTSAG MVGRIIGYTK ANVGYAHPYF HAAKRRNCDG DEDSFFLLLD
910 920 930 940 950 960
AFLNFSKKFL PDKRGGQMDA PLVLTTILDP KEVDGEVHNM DTMWSYPLEF YEKTLEMPSP
970 980 990 1000 1010 1020
KEVKEFMETV EDRLGKPEQY EGIGYTHETS RIDLGPKVCA YKTLGSMLEK TTSQLSVAKK
1030 1040 1050 1060 1070 1080
IRATDERDVA EKVIQSHFIP DLIGNLRAFS RQAVRCKCGA KYRRIPLKGK CPKCGSNLIL
1090 1100 1110 1120 1130
TVSKGAVEKY MDVAEKMAEE YNVNDYIKQR LKIIKEGINS IFENEKSRQV KLSDFFKIG
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Q59024 in FASTA format |
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