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[1]
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NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Bristol N2;
DOI=10.1126/science.282.5396.2012; PubMed=9851916 [NCBI, ExPASy, EBI, Israel, Japan]
The C. elegans sequencing consortium;
"Genome sequence of the nematode C. elegans: a platform for investigating biology.";
Science 282:2012-2018(1998).
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[2]
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X-RAY CRYSTALLOGRAPHY (1.77 ANGSTROMS) OF 135-229.
DOI=10.1074/jbc.M208512200; PubMed=12221106 [NCBI, ExPASy, EBI, Israel, Japan]
Li S.,
Finley J.,
Liu Z.J.,
Qiu S.H.,
Chen H.,
Luan C.H.,
Carson M.,
Tsao J.,
Johnson D.,
Lin G.,
Zhao J.,
Thomas W.,
Nagy L.A.,
Sha B.,
DeLucas L.J.,
Wang B.C.,
Luo M.;
"Crystal structure of the cytoskeleton-associated protein glycine-rich (CAP-Gly) domain.";
J. Biol. Chem. 277:48596-48601(2002).
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[3]
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STRUCTURE BY NMR OF 1-120.
DOI=10.1074/jbc.M409422200; PubMed=15364906 [NCBI, ExPASy, EBI, Israel, Japan]
Lytle B.L.,
Peterson F.C.,
Qiu S.H.,
Luo M.,
Zhao Q.,
Markley J.L.,
Volkman B.F.;
"Solution structure of a ubiquitin-like domain from tubulin-binding cofactor B.";
J. Biol. Chem. 279:46787-46793(2004).
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- FUNCTION: Binds to alpha-tubulin folding intermediates after their interaction with cytosolic chaperonin in the pathway leading from newly synthesized tubulin to properly folded heterodimer (By similarity).
- SUBUNIT: Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state (By similarity).
- SUBCELLULAR LOCATION: Cytoplasm (By similarity). Cytoplasm, cytoskeleton (By similarity).
- SIMILARITY: Belongs to the TBCB family.
- SIMILARITY: Contains 1 CAP-Gly domain.
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Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms.
Distributed under the Creative Commons Attribution-NoDerivs License.
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| Length: 229 AA [This is the length of the unprocessed precursor] |
Molecular weight: 25441 Da [This is the MW of the unprocessed precursor] |
CRC64: C465365DAE378A0F [This is a checksum on the sequence] |
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10 20 30 40 50 60
MTEVYDLEIT TNATDFPMEK KYPAGMSLND LKKKLELVVG TTVDSMRIQL FDGDDQLKGE
70 80 90 100 110 120
LTDGAKSLKD LGVRDGYRIH AVDVTGGNED FKDESMVEKY EMSDDTYGKR TDSVRAWKKK
130 140 150 160 170 180
MQEEQGSAAP MENESDKLNE EAAKNIMVGN RCEVTVGAQM ARRGEVAYVG ATKFKEGVWV
190 200 210 220
GVKYDEPVGK NDGSVAGVRY FDCDPKYGGF VRPVDVKVGD FPELSIDEI
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Q20728 in FASTA format |
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ExPASy Home page
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