[1]	PROTEIN SEQUENCE. TISSUE=Venom; PubMed=9531050 [NCBI, ExPASy, EBI, Israel, Japan] Kowalska M.A., Tan L., Holt J.C., Peng M., Karczewski J., Calvete J.J., Niewiarowski S.; "Alboaggregins A and B. Structure and interaction with human platelets."; Thromb. Haemost. 79:609-613(1998).

Comments

FUNCTION: Binds to platelet GPIb/IX receptor system and stimulates agglutination.
SUBUNIT: Heterotetramer of the subunits 1, 2, 3 and 4, disulfide-linked.
SUBCELLULAR LOCATION: Secreted.
TISSUE SPECIFICITY: Expressed by the venom gland.
SIMILARITY: Contains 1 C-type lectin domain.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

3D structure databases

HSSP

P22030; 1IJK. [HSSP ENTRY / PDB]

SMR

P81113; 1-123.

ModBase

P81113.

Ontologies

GO:0005576;	Cellular component: extracellular region (inferred from electronic annotation from UniProtKB-KW).
GO:0005529;	Molecular function: sugar binding (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.

Family and domain databases

InterPro

IPR001304; C-type_lectin.
IPR016186; C-type_lectin-like.
Graphical view of domain structure.

Gene3D

G3DSA:3.10.100.10; C-type_lectin-like; 1.

Pfam

PF00059; Lectin_C; 1.
Pfam graphical view of domain structure.

SMART

SM00034; CLECT; 1.
SMART graphical view of domain structure.

PROSITE

PS00615; C_TYPE_LECTIN_1; FALSE_NEG.
PS50041; C_TYPE_LECTIN_2; 1.
PROSITE graphical view of domain structure (profiles).

ProtoNet

P81113.

Phylogenomic databases

HOVERGEN

P81113; -.

Other

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Direct protein sequencing; Lectin; Secreted.

Features

Feature table viewer

Feature aligner

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 125`	`125`	`Alboaggregin-A subunit 3.`	`PRO_0000046710`
`DOMAIN`	`1 125`	`125`	`C-type lectin.`
`DISULFID`	`4 15`		`By similarity.`
`DISULFID`	`32 121`		`By similarity.`
`DISULFID`	`98 113`		`By similarity.`

Sequence information

Length: 125 AA [This is the length of the unprocessed precursor]

Molecular weight: 14799 Da [This is the MW of the unprocessed precursor]

CRC64: CAFA24C098DF3293 [This is a checksum on the sequence]

        10         20         30         40         50         60 
GFDCPFGWSS YEGYCYKVYN KKMNWEDAES FCREQHKRSH LVSFHSSGEV DFVVSKTFPI 

        70         80         90        100        110        120 
LRYDFVWMGL SDIWKECTKE WSDGARLDYK AWSGKSYCLV SKTTNNEWLS MDCSRTRYPV 


CKFXG

P81113 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools