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UniProtKB/Swiss-Prot entry P74572


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name P5CR_SYNY3
Primary accession number P74572
Secondary accession numbers None
Integrated into Swiss-Prot on July 15, 1998
Sequence was last modified on February 1, 1997 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 46)
Name and origin of the protein
Protein name Pyrroline-5-carboxylate reductase
Synonyms P5C reductase
P5CR
EC 1.5.1.2
Gene name
Name: proC
OrderedLocusNames: slr0661
From
Synechocystis sp. (strain PCC 6803) [TaxID: 1148] [HAMAP proteome]
Taxonomy Bacteria; Cyanobacteria; Chroococcales; Synechocystis.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1093/dnares/3.3.109; PubMed=8905231 [NCBI, ExPASy, EBI, Israel, Japan]
Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S., Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.;
"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions.";
DNA Res. 3:109-136(1996).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
BA000022; BAA18679.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR S76767; S76767.
RefSeq NP_442867.1; -.
3D structure databases
ModBase P74572.
Protein-protein interaction databases
IntAct P74572; -.
Enzyme and pathway databases
BioCyc SSP1148:SLR0661-MON; -.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from UniProtKB-KW).
GO:0005488; Molecular function: binding (inferred from electronic annotation from InterPro).
GO:0004735; Molecular function: pyrroline-5-carboxylate reductase activity (inferred from electronic annotation from InterPro).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
GO:0006561; Biological process: proline biosynthetic process (inferred from electronic annotation from InterPro).
QuickGo view.
Family and domain databases
InterPro IPR004455; NADP_OxRdtase_F420.
IPR000304; P5CR.
Graphical view of domain structure.
PANTHER PTHR11645; P5CR; 1.
Pfam PF03807; F420_oxidored; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000193; Pyrrol-5-carb_rd; 1.
TIGRFAMs TIGR00112; proC; 1.
PROSITE PS00521; P5CR; 1.
ProtoNet P74572.
Genome annotation databases
GeneID 952360; -.
GenomeReviews BA000022_GR; slr0661.
KEGG syn:slr0661; -.
NMPDR fig|1148.1.peg.2968; -.
Phylogenomic databases
HOGENOM P74572; -.
Genome annotation databases
CMR P74572; slr0661.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Amino-acid biosynthesis; Complete proteome; Cytoplasm; NADP; Oxidoreductase; Proline biosynthesis.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   267  267     Pyrroline-5-carboxylate reductase. PRO_0000187308
Sequence information
Length: 267 AA [This is the length of the unprocessed precursor] Molecular weight: 27883 Da [This is the MW of the unprocessed precursor] CRC64: FD9C428047F391B0 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MSIQLGIIGG GVMAEAILAR LIAEKTYAPE EIIVGEPHGA RRDYLQKTYQ VRVSPDNQEA 

        70         80         90        100        110        120 
ANVSEVLLLA VKPQVLDRVL ASLAGGANRP LVISILAGVS LQRIQKGFPD HAIIRAMPNT 

       130        140        150        160        170        180 
PATVGAGMTA IAANKMVEPD QLAKAKAIFS AVGNVVEVPE NLMDAVTGVS GSGPAYVALM 

       190        200        210        220        230        240 
IEALADGGVL AGLPRAIAQK LALQTVLGTA ELIKETEEHP AQIKDKVTSP GGTTIAGVAV 

       250        260 
LEKMGFRSAI IEAVRAAYRR SQELGKK 

P74572 in FASTA format

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BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA)
Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

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