NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1093/dnares/3.3.109; PubMed=8905231 [NCBI, ExPASy, EBI, Israel, Japan]
Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S., Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.;
"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions.";
DNA Res. 3:109-136(1996).

Comments

FUNCTION: Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity).
CATALYTIC ACTIVITY: ATP + NAD⁺ = ADP + NADP⁺.
COFACTOR: Divalent metal ions (By similarity).
SUBCELLULAR LOCATION: Cytoplasm (By similarity).
SIMILARITY: Belongs to the NAD kinase family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

BA000022; BAA18530.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

PIR

S76401; S76401.

RefSeq

NP_441852.1; -.

3D structure databases

ModBase

P74430.

Enzyme and pathway databases

BioCyc

SSP1148:SLR0400-MON; -.

Ontologies

GO:0005737;	Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0046872;	Molecular function: metal ion binding (inferred from electronic annotation from HAMAP).
GO:0003951;	Molecular function: NAD+ kinase activity (inferred from electronic annotation from HAMAP).
GO:0008152;	Biological process: metabolic process (inferred from electronic annotation from InterPro).
QuickGo view.

Family and domain databases

HAMAP

MF_00361; -; 1.
PBIL [Tree]

InterPro

IPR017437; ATP-NAD_kinase_PpnK-typ_all-b.
IPR002504; ATP_NADK.
Graphical view of domain structure.

Gene3D

G3DSA:2.60.200.30; ATP-NAD_kinase_PpnK-typ; 1.

PANTHER

PTHR20275; ATP_NADK; 1.

Pfam

PF01513; NAD_kinase; 1.
Pfam graphical view of domain structure.

ProtoNet

P74430.

Genome annotation databases

GeneID

952880; -.

GenomeReviews

BA000022_GR; slr0400.

KEGG

syn:slr0400; -.

NMPDR

fig|1148.1.peg.1953; -.

Phylogenomic databases

HOGENOM

P74430; -.

Genome annotation databases

CMR

P74430; slr0400.

Other

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Complete proteome; Cytoplasm; Kinase; NAD; NADP; Transferase.

Features

Feature table viewer

`Key`	`From To`	`Length`		`Description`	`FTId`
`CHAIN`	`1 305`	`305`		`Probable inorganic polyphosphate/ATP-NAD kinase 1.`	`PRO_0000120678`

Sequence information

Length: 305 AA [This is the length of the unprocessed precursor]

Molecular weight: 33398 Da [This is the MW of the unprocessed precursor]

CRC64: 695ED7EA16244E2C [This is a checksum on the sequence]

        10         20         30         40         50         60 
MPKVGIIFND DKPTACSVAQ ELQEQLQQSG FTVAMETGSG GLLGYSQPDR PICHTRIEHL 

        70         80         90        100        110        120 
TPPHFDESMP FAIVLGGDGT VLSAFRQLAP LGIPLLTINT GHMGFLTEIY LNQLPTAIEQ 

       130        140        150        160        170        180 
LINGDYQIES RSMMTVRLMR EENLLWEALS LNEMVLHREP LTSMCHFEIQ VGYHASVDIA 

       190        200        210        220        230        240 
ADGIIVSTPT GSTAYSLSAG GPVVTPDVPV FQLAPICPHS LASRALVFSD LEPVTIFPAT 

       250        260        270        280        290        300 
PNRMVLVVDG NGGCYVLPED RVHLSKSPYP AKFIRLQTPE FFRILREKLG WGLPHIAKPT 


SVELP

P74430 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools