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[1]
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NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=LT2 / SGSC1412 / ATCC 700720;
DOI=10.1038/35101614; PubMed=11677609 [NCBI, ExPASy, EBI, Israel, Japan]
McClelland M.,
Sanderson K.E.,
Spieth J.,
Clifton S.W.,
Latreille P.,
Courtney L.,
Porwollik S.,
Ali J.,
Dante M.,
Du F.,
Hou S.,
Layman D.,
Leonard S.,
Nguyen C.,
Scott K.,
Holmes A.,
Grewal N.,
Mulvaney E.,
Ryan E., ![]()
Sun H.,
Florea L.,
Miller W.,
Stoneking T.,
Nhan M.,
Waterston R.,
Wilson R.K.;
"Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
Nature 413:852-856(2001).
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- FUNCTION: Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'-monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP. Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain-length substrates (P20-25). Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3'-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs (By similarity).
- CATALYTIC ACTIVITY: A 5'-ribonucleotide + H2O = a ribonucleoside + phosphate.
- CATALYTIC ACTIVITY: A 3'-ribonucleotide + H2O = a ribonucleoside + phosphate.
- CATALYTIC ACTIVITY: (Polyphosphate)(n) + H2O = (polyphosphate)(n-1) + phosphate.
- COFACTOR: Binds 1 divalent metal cation per subunit (By similarity).
- SUBCELLULAR LOCATION: Cytoplasm (Potential).
- SIMILARITY: Belongs to the surE nucleotidase family.
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Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms.
Distributed under the Creative Commons Attribution-NoDerivs License.
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| Length: 253 AA [This is the length of the unprocessed precursor] |
Molecular weight: 26980 Da [This is the MW of the unprocessed precursor] |
CRC64: A8C4DD6EE42372F8 [This is a checksum on the sequence] |
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10 20 30 40 50 60
MRILLSNDDG VHAPGIQTLA KALREFADVQ VVAPDRNRSG ASNSLTLESS LRTFTFDNGD
70 80 90 100 110 120
IAVQMGTPTD CVYLGVNALM RPRPDIVVSG INAGPNLGDD VIYSGTVAAA MEGRHLGFPA
130 140 150 160 170 180
LAVSLNGYQH YDTAAAVTCA LLRGLSREPL RTGRILNVNV PDLPLAQVKG IRVTRCGSRH
190 200 210 220 230 240
PADKVIPQED PRGNTLYWIG PPGDKYDAGP DTDFAAVDEG YVSVTPLHVD LTAHSAHDVV
250
SDWLDSVGVG TQW
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P66881 in FASTA format |
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