NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=CHA0;
PubMed=8526497 [NCBI, ExPASy, EBI, Israel, Japan]
Schnider U., Keel C., Defago G., Haas D.;
"Tn5-directed cloning of pqq genes from Pseudomonas fluorescens CHA0: mutational inactivation of the genes results in overproduction of the antibiotic pyoluteorin.";
Appl. Environ. Microbiol. 61:3856-3864(1995).

Comments

FUNCTION: Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ (By similarity).
CATALYTIC ACTIVITY: 6-(2-amino-2-carboxyethyl)-7,8-dioxo-1,2,3,4,7,8-hexahydroquinoline-2,4-dicarboxylate + 3 O₂ = 4,5-dioxo-4,5-dihydro-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylate + 2 H₂O₂ + 2 H₂O.
PATHWAY: Cofactor biosynthesis; pyrroloquinoline quinone biosynthesis .
SIMILARITY: Belongs to the pqqC family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

X87299; CAA60734.1; -; Genomic_DNA.

S58244; S58244.

3D structure databases

Ontologies

GO:0033732;	Molecular function: pyrroloquinoline-quinone synthase activity (inferred from electronic annotation from EC).
GO:0055114;	Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
GO:0018189;	Biological process: pyrroloquinoline quinone biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.

Family and domain databases

MF_00654; -; 1.
PBIL [Tree]

Other

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Oxidoreductase; PQQ biosynthesis.

Features

Feature table viewer

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 >11`	`>11`	`Pyrroloquinoline-quinone synthase.`	`PRO_0000219983`
`NON_TER`	`11 11`

Sequence information

Length: 11 AA [This is the length of the partial sequence of the unprocessed precursor]

Molecular weight: 1182 Da [This is the MW of the partial sequence of the unprocessed precursor]

CRC64: 89DF46E4C5B73771 [This is a checksum on the sequence]

        10 
MTDTPLSAAE F

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools