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UniProtKB/Swiss-Prot entry P39616


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name ALDH2_BACSU
Primary accession number P39616
Secondary accession numbers None
Integrated into Swiss-Prot on February 1, 1995
Sequence was last modified on February 1, 1995 (Sequence version 1)
Annotations were last modified on    November 4, 2008 (Entry version 61)
Name and origin of the protein
Protein name Probable aldehyde dehydrogenase ywdH
Synonym EC 1.2.1.3
Gene name
Name: ywdH
OrderedLocusNames: BSU37960
ORFNames: ipa-58r
From
Bacillus subtilis [TaxID: 1423] [HAMAP proteome]
Taxonomy Bacteria; Firmicutes; Bacillales; Bacillaceae; Bacillus.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=168;
DOI=10.1111/j.1365-2958.1993.tb01963.x; PubMed=7934828 [NCBI, ExPASy, EBI, Israel, Japan]
Glaser P., Kunst F., Arnaud M., Coudart M.P., Gonzales W., Hullo M.-F., Ionescu M., Lubochinsky B., Marcelino L., Moszer I., Presecan E., Santana M., Schneider E., Schweizer J., Vertes A., Rapoport G., Danchin A.;
"Bacillus subtilis genome project: cloning and sequencing of the 97 kb region from 325 degrees to 333 degrees.";
Mol. Microbiol. 10:371-384(1993).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=168;
DOI=10.1038/36786; PubMed=9384377 [NCBI, ExPASy, EBI, Israel, Japan]
Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S., Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K., Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F., Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D., Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M., Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P., Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K., Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S., Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y., Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G., Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J., Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C., Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S., Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B., Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S., Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M., Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y., Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J., Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A., Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M., Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S., Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E., Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K., Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E., Yoshikawa H., Danchin A.;
"The complete genome sequence of the Gram-positive bacterium Bacillus subtilis.";
Nature 390:249-256(1997).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
X73124; CAA51614.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
Z99123; CAB15822.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR S39713; S39713.
RefSeq NP_391675.1; -.
3D structure databases
HSSP P11883; 1AD3. [HSSP ENTRY / PDB]
ModBase P39616.
Enzyme and pathway databases
BioCyc BSUB224308:BSU3792-MON; -.
Organism-specific databases
SubtiList BG10604; ywdH. [Micado]
Ontologies
GO
GO:0004029; Molecular function: aldehyde dehydrogenase (NAD) activity (inferred from electronic annotation from EC).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
InterPro IPR016160; Ald_DHase_CS.
IPR016162; Ald_DHase_N.
IPR012394; Ald_DHase_NAD(P).
IPR015590; Aldehyde_DHase.
Graphical view of domain structure.
Gene3D G3DSA:3.40.605.10; Aldehyde_dehydrogenase_N; 1.
PANTHER PTHR11699; Aldehyde_dehyd; 1.
PTHR11699:SF15; ALDH; 1.
Pfam PF00171; Aldedh; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF036492; ALDH; 1.
PROSITE PS00070; ALDEHYDE_DEHYDR_CYS; 1.
PS00687; ALDEHYDE_DEHYDR_GLU; 1.
BLOCKS P39616.
ProtoNet P39616.
Genome annotation databases
GeneID 937252; -.
GenomeReviews AL009126_GR; BSU37960.
KEGG bsu:BSU37960; -.
NMPDR fig|224308.1.peg.3801; -.
Phylogenomic databases
HOGENOM P39616; -.
Genome annotation databases
CMR P39616; BSU37960.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; NAD; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   457  457     Probable aldehyde dehydrogenase ywdH. PRO_0000056445
ACT_SITE   211   211        By similarity. 
ACT_SITE   245   245        By similarity. 
Sequence information
Length: 457 AA [This is the length of the unprocessed precursor] Molecular weight: 50766 Da [This is the MW of the unprocessed precursor] CRC64: C238D9FD07DFB92A [This is a checksum on the sequence]
        10         20         30         40         50         60 
MNSSIPSIIS KHKAYFAAGH TRPLESRLNI LRKLKQAVRT HEADLIAALY QDLHKSEQEA 

        70         80         90        100        110        120 
YSTEIGIVLE EISFVMKRLR KWSKPKRVKT PLTHLGSKSI IIPEPYGTVL VIAPWNYPLQ 

       130        140        150        160        170        180 
LALSPLIGAI AAGNTVVLKP SEYTPAVSAI LSKLISSVFP TDYVAMAEGG PDVSTALLQQ 

       190        200        210        220        230        240 
PFDYIFFTGS VAVGKIVMEA AAKQLIPVTL ELGGKSPCIV HKDADIQLAA KRIVFGKFTN 

       250        260        270        280        290        300 
AGQTCIAPDY LFVHEDIKTK LTEEMKRAIR EFYGPQPERN PQYGKIVSER HYQRLLSFLN 

       310        320        330        340        350        360 
DGIPLTGGQS DPNHHKIAPT ILEQVRDDSP VMQEEIFGPI LPLFTYRNIG EVIEKVQSRP 

       370        380        390        400        410        420 
KPLALYLFTT NKEIERAVLG NLSFGGGCVN DTLMHVATPY LPFGGVGESG IGSYHGFDSF 

       430        440        450 
NTFTHKKSVV KQTNRFDFAF RYPSSKNGLR MIRKILK 

P39616 in FASTA format

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BLAST logo BLAST submission on ExPASy/SIB
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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
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