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UniProtKB/Swiss-Prot entry P06130

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name FDHB_METFO
Primary accession number P06130
Secondary accession numbers None
Integrated into Swiss-Prot on January 1, 1988
Sequence was last modified on January 1, 1988 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 58)
Name and origin of the protein
Protein name Formate dehydrogenase beta chain
Synonym EC 1.2.1.2
Gene name
Name: fdhB
From
Methanobacterium formicicum [TaxID: 2162] 
Taxonomy Archaea; Euryarchaeota; Methanobacteria; Methanobacteriales; Methanobacteriaceae; Methanobacterium.
Protein existence 1: Evidence at protein level;
References
[1]
 NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND PROTEIN SEQUENCE OF 1-22.
STRAIN=JF-1;
PubMed=3531194 [NCBI, ExPASy, EBI, Israel, Japan]
Shuber A.P., Orr E.C., Recny M.A., Schendel P.F., May H.D., Schauer N.L., Ferry J.G.;
"Cloning, expression, and nucleotide sequence of the formate dehydrogenase genes from Methanobacterium formicicum.";
J. Biol. Chem. 261:12942-12947(1986).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
J02581; AAA72183.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR B24698; B24698.
3D structure databases
ModBase P06130.
Ontologies
GO
GO:0051539; Molecular function: 4 iron, 4 sulfur cluster binding (inferred from electronic annotation from UniProtKB-KW).
GO:0009055; Molecular function: electron carrier activity (inferred from electronic annotation from InterPro).
GO:0008863; Molecular function: formate dehydrogenase activity (inferred from electronic annotation from EC).
GO:0005506; Molecular function: iron ion binding (inferred from electronic annotation from UniProtKB-KW).
GO:0022900; Biological process: electron transport chain (inferred from electronic annotation from UniProtKB-KW).
GO:0006810; Biological process: transport (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
InterPro IPR001450; 4Fe4S_Fe_S_bd.
IPR007516; Co_F420_Hydgase/DHase_bsu_N.
IPR007525; FrhB_FdhB_C.
IPR012285; Fum_reductase_C.
Graphical view of domain structure.
Gene3D G3DSA:1.10.1060.10; Fum_reductase_C; 1.
Pfam PF00037; Fer4; 1.
PF04432; FrhB_FdhB_C; 1.
PF04422; FrhB_FdhB_N; 1.
Pfam graphical view of domain structure.
PROSITE PS00198; 4FE4S_FER_1; 2.
PS51379; 4FE4S_FER_2; 2.
PROSITE graphical view of domain structure (profiles).
ProtoNet P06130.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
4Fe-4S; Direct protein sequencing; Electron transport; Iron; Iron-sulfur; Metal-binding; NAD; Oxidoreductase; Repeat; Transport.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   399  399     Formate dehydrogenase beta chain. PRO_0000159222
DOMAIN   287   316  30     4Fe-4S ferredoxin-type 1. 
DOMAIN   339   367  29     4Fe-4S ferredoxin-type 2. 
METAL   296   296        Iron-sulfur (4Fe-4S) (By similarity). 
METAL   299   299        Iron-sulfur (4Fe-4S) (By similarity). 
METAL   302   302        Iron-sulfur (4Fe-4S) (By similarity). 
METAL   306   306        Iron-sulfur (4Fe-4S) (By similarity). 
METAL   348   348        Iron-sulfur (4Fe-4S) (By similarity). 
METAL   351   351        Iron-sulfur (4Fe-4S) (By similarity). 
METAL   354   354        Iron-sulfur (4Fe-4S) (By similarity). 
METAL   358   358        Iron-sulfur (4Fe-4S) (By similarity). 
Sequence information
Length: 399 AA [This is the length of the unprocessed precursor] Molecular weight: 43922 Da [This is the MW of the unprocessed precursor] CRC64: D57F778C6C8F67BB [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MINTNDMFYA KSSDAEIAEA GEYGGAVTTL LKFLLKEGIV DAVLAVDSSA DLYDVVPILI 

        70         80         90        100        110        120 
EDPEDVVKAA GSLHFGTLNL AKVVTRYLDG AQDMKIAVTV KPCDAMTMVE LMKREKVNAD 

       130        140        150        160        170        180 
NVIMVGLNCG GTMPPVKGRQ MMEEFYEVDP DSVVKEEIAK GKLIVETEDG TEKEIPIDEL 

       190        200        210        220        230        240 
EDEGFGRRTN CRRCEVNIPR MADLACGNWG VIGPLAGKAT FIEVCSPKGA EVLEKAKEAG 

       250        260        270        280        290        300 
VIDLEDPIPK GIEIREKIDG AMVKLADKWQ GNDWEDKAGR EIFSVLTEYM DDFSRCLKCY 

       310        320        330        340        350        360 
GCREACPICY CEDCCLEANN GPDWLSKGEI PPSPMFHLER MLHMVESCTN CGQCEEVCPG 

       370        380        390 
EIPLAKIWHE VNAKMKDTFG YVKGTGDEKP PIAYFPVGK
P06130 in FASTA format

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