NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1371/journal.pone.0001271; PubMed=18060065 [NCBI, ExPASy, EBI, Israel, Japan]
Smith T.J., Hill K.K., Foley B.T., Detter J.C., Munk A.C., Bruce D.C., Doggett N.A., Smith L.A., Marks J.D., Xie G., Brettin T.S.;
"Analysis of the neurotoxin complex genes in Clostridium botulinum A1-A4 and B1 strains: BoNT/A3, /Ba4 and /B1 clusters are located within plasmids.";
PLoS ONE 2:E1271-E1271(2007).

Comments

CATALYTIC ACTIVITY: ATP + acetate = ADP + acetyl phosphate.
CATALYTIC ACTIVITY: ATP + propanoate = ADP + propanoyl phosphate.
PATHWAY: Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2 .
SUBCELLULAR LOCATION: Cytoplasm (By similarity).
SIMILARITY: Belongs to the acetokinase family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

CP000726; ABS32709.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

RefSeq

YP_001384635.1; -.

3D structure databases

ModBase

A7FW24.

Ontologies

GO:0005737;	Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0008776;	Molecular function: acetate kinase activity (inferred from electronic annotation from HAMAP).
GO:0016310;	Biological process: phosphorylation (inferred from electronic annotation from HAMAP).
QuickGo view.

Family and domain databases

HAMAP

MF_00020; -; 1.
PBIL [Tree]

InterPro

IPR000890; Acetate_kin.
IPR004372; AckA.
Graphical view of domain structure.

PANTHER

PTHR21060; Acetate_kin; 1.
PTHR21060:SF11; AckA; 1.

Pfam

PF00871; Acetate_kinase; 1.
Pfam graphical view of domain structure.

PIRSF

PIRSF000722; Acetate_prop_kin; 1.

PRINTS

PR00471; ACETATEKNASE.

TIGRFAMs

TIGR00016; ackA; 1.

PROSITE

PS01075; ACETATE_KINASE_1; 1.
PS01076; ACETATE_KINASE_2; 1.

Genome annotation databases

GeneID

5396212; -.

GenomeReviews

CP000726_GR; CLB_2324.

KEGG

cba:CLB_2324; -.

CMR

A7FW24; CLB_2324.

Other

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Complete proteome; Cytoplasm; Kinase; Transferase.

Features

Feature table viewer

`Key`	`From To`	`Length`		`Description`	`FTId`
`CHAIN`	`1 397`	`397`		`Acetate kinase.`	`PRO_1000002220`

Sequence information

Length: 397 AA [This is the length of the unprocessed precursor]

Molecular weight: 43430 Da [This is the MW of the unprocessed precursor]

CRC64: AEA792DAF684F2DA [This is a checksum on the sequence]

        10         20         30         40         50         60 
MKILVVNCGS SSLKYQLIDM TSEEALAKGL VERIGIEGSI LTQKVNGEKY IIEEPMKDHK 

        70         80         90        100        110        120 
KAIELVLKAL VDKEHGVISD MSEIAAVGHR VVHGGEKYAS SVLINDEVMK ALEDCVKLAP 

       130        140        150        160        170        180 
LHNPPNIIGI NACRELMPKT PMVAVFDTAF HQTLPDYAYM YPLPYELYEQ NGIRKYGFHG 

       190        200        210        220        230        240 
TSHRYVSSVA SEMMGKDLKD LKVITCHLGN GASLCAVKEG KSVETSMGFT PLAGLAMGTR 

       250        260        270        280        290        300 
CGDIDPAILL FMERELKMSP DEVDTVINKK SGVLGISGVS SDFRDIEGAA EEGNKRAKLA 

       310        320        330        340        350        360 
LDVYHYTVRQ TIGAYTAVLN GVDAIVFTAG LGENSAASRE EILNGLEYLG IKIDAEKNKQ 

       370        380        390 
RGKQIEISTE DSKVKVFVIP TDEELMIARD TKEITVK

A7FW24 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools