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HAMAP: Treponema pallidum complete proteome

General information

Species:  Treponema pallidum
Species code: TREPA
Taxonomy: Bacteria; Spirochaetes; Spirochaetales; Spirochaetaceae; Treponema (TaxID: 160) [NEWT/ NCBI]
Description: Treponema pallidum (Spirochete), is a helical to sinusoidal bacterium with 2 membranes, a thin peptidoglycan layer and flagella that lie in the periplasmic space. It is the causative agent of syphilis. Even if the primary infection is localized, bacteria rapidly disseminate and cause manifestations in the cardiovascular and nervous systems. It is an obligate human parasite.
Properties: Presence of flagella: Yes
Human pathogen: Yes
Interaction: Animal pathogen in Mammalia
Number of membranes: 2
Number of inteins:0
Statistics: Number of TREPA entries in the UniProt Knowledgebase: 1028 (615 in UniProtKB/Swiss-Prot + 413 in UniProtKB/TrEMBL)


Genome(s) sequenced

Strain:    Nichols
Genome structure:
Chromosome EMBL accession number AE000520 (circular; 1,138,011 bp) (download entry) (download Genome Reviews).
Reference(s):
[1] MEDLINE=98332770; PubMed=9665876; [ NCBI , EBI , Israel , Japan ]
Fraser C.M., Norris S.J., Weinstock G.M., White O., Sutton G.G., Dodson R.J., Gwinn M.L., Hickey E.K., Clayton R.A., Ketchum K.A., Sodergren E., Hardham J.M., McLeod M.P., Salzberg S.L., Peterson J.D., Khalak H.G., Richardson D.L., Howell J.K., Chidambaram M., Utterback T.R., McDonald L.A., Artiach P., Bowman C., Cotton M.D., Fujii C., Garland S.A., Hatch B., Horst K., Roberts K.M., Sandusky M., Weidman J.F., Smith H.O., Venter J.C. ;
"Complete genome sequence of Treponema pallidum, the syphilis spirochete.";
Science 281:375-388(1998).
Web links:
CBS: http://www.cbs.dtu.dk/services/GenomeAtlas/show-genus.php?kingdom=Bacteria&GLgenus=Treponema&GLspecies=pallidum&GLstrain=Nichols
Entrez Genome Project: http://www.ncbi.nlm.nih.gov/sites/entrez?Db=genomeprj&Cmd=DetailsSearch&Term=txid243276%5Borgn%5D
GIB (DDBJ): http://gib.genes.nig.ac.jp/single/index.php?spid=Tpal_NICHOLS
Karyn's Genomes: http://www.ebi.ac.uk/2can/genomes/bacteria/Treponema_pallidum.html
NMPDR: http://www.nmpdr.org/FIG/seedviewer.cgi?pattern=243276.1;page=SearchResult
PEDANT: http://pedant.gsf.de:3345/pedant3htmlview/pedant3view?Method=start_method&Db=p3_p5_Tre_palli
TIGR CMR: http://cmr.tigr.org/tigr-scripts/CMR/GenomePage.cgi?database=gtp
 EBI Proteome Analysis page



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