Species code:	BRUSU
Taxonomy:	Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales; Brucellaceae; Brucella (TaxID: 29461) [NEWT/ NCBI]
Description:	Brucellosis is a major infectious disease for both human and animals. Several Brucella species (B.abortus, B.melitensis and B.suis) have been isolated from many different animals. All three Brucella species cause a severe human disease characterized in its acute phase by undulant fever and in its chronic phase by damage of different organs. When the infection is localized to the brain or the heart, it can result in a fatal meningitidis or fatal endocarditis, respectively. Brucellosis is a major problem in the Mediterranean region and parts of Asia, Africa and Latin America. Brucella suis was the first pathogenic organism weaponized by the U.S. military during the 1950s. Although Brucellae contain a large set of flagellar genes, they display a species-specific gene inactivation and consequently are nonmotile.
Properties:	Presence of flagella: No Interaction: Animal pathogen in Mammalia Number of membranes: 2 Number of inteins:0
Statistics:	Number of BRUSU entries in the UniProt Knowledgebase: 3256 (535 in UniProtKB/Swiss-Prot + 2721 in UniProtKB/TrEMBL)

Genome structure	• Chromosome I EMBL accession number AE014291 (circular; 2,107,794 bp) (download entry) (download Genome Reviews). • Chromosome II EMBL accession number AE014292 (circular; 1,207,381 bp) (download entry) (download Genome Reviews).
References	[1] MEDLINE=22247741; PubMed=12271122; [ NCBI , EBI , Israel , Japan ] Paulsen I.T., Seshadri R., Nelson K.E., Eisen J.A., Heidelberg J.F., Read T.D., Dodson R.J., Umayam L.A., Brinkac L.M., Beanan M.J., Daugherty S.C., DeBoy R.T., Durkin A.S., Kolonay J.F., Madupu R., Nelson W.C., Ayodeji B., Kraul M., Shetty J., Malek J.A., Van Aken S.E., Riedmuller S., Tettelin H., Gill S.R., White O., Salzberg S.L., Hoover D.L., Lindler L.E., Halling S.M., Boyle S.M., Fraser C.M. ; "The Brucella suis genome reveals fundamental similarities between animal and plant pathogens and symbionts."; Proc. Natl. Acad. Sci. U.S.A. 99:13148-13153(2002).
Web links	CBS: http://www.cbs.dtu.dk/services/GenomeAtlas/show-genus.php?kingdom=Bacteria&GLgenus=Brucella&GLspecies=Suis&GLstrain=1330 Entrez Genome Project: http://www.ncbi.nlm.nih.gov/sites/entrez?Db=genomeprj&Cmd=DetailsSearch&Term=txid204722%5Borgn%5D GIB (DDBJ): http://gib.genes.nig.ac.jp/single/index.php?spid=Bsui_1330 Karyn's Genomes: http://www.ebi.ac.uk/2can/genomes/bacteria/Brucella_suis.html PATRIC: http://patric.vbi.vt.edu/genome/overview.php?genomeId=7 PEDANT: http://pedant.gsf.de:3345/pedant3htmlview/pedant3view?Method=start_method&Db=p3_p320_Bru_suis RhizoDB: http://xbase.bham.ac.uk/rhizodb/genome.pl?id=970 TIGR CMR: http://cmr.tigr.org/tigr-scripts/CMR/GenomePage.cgi?database=gbr  EBI Proteome Analysis page

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