Species code:	BART1
Taxonomy:	Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales; Bartonellaceae; Bartonella (TaxID: 382640) [NEWT/ NCBI]
Description:	Bartonella sp. are alphaproteobacteria known to be involved in mammalian diseases of varying gravity, including cat scratch fever, endocarditis and bartonellosis. They are transmitted by insect vectors and survive in mammalian reservoir hosts. A variety of Bartonella have been isolated from different mammalian hosts in both Europe and the Americas. They grow facultatively within erythrocytes and vascular epithelial cells. B.tribocorum strain was isolated from a wild rat (R.norvegicus) near the Rhine River in France. It has not yet been observed to be a human pathogen. It is aerobic, has no flagella, but seems to have polar fimbriae, and is catalase, oxidase and urease negative. Comparative analyses of the 4 available (December 2007; B.tribocorum, B.henselae, B.quintana and B.bacilliformis) Bartonella genomes indicates that the presence of 2 type IV secretion systems (virB and trw) which have been acquired by lateral gene transfer since B.tribocorum, B.henselae, and B.quintana separated from B.bacilliformis. As B.bacilliformis is very virulent it is suggested that these type IV secretion system may be involved in virulence attenuation and increased host range (modified from PubMed 9828434 and 18037886).
Properties:	Presence of flagella: No Interaction: Animal pathogen in Mammalia Number of membranes: 2 Number of inteins:0
Statistics:	Number of BART1 entries in the UniProt Knowledgebase: 1962 (227 in UniProtKB/Swiss-Prot + 1735 in UniProtKB/TrEMBL)

Genome structure:	• Chromosome EMBL accession number AM260525 (circular; 2,619,061 bp) (download entry) (download Genome Reviews). • Plasmid pBT EMBL accession number AM260524 (circular; 23,343 bp) (download entry) (download Genome Reviews).
Reference(s):	[1] PubMed=18037886; [ NCBI , EBI , Israel , Japan ] Saenz H.L., Engel P., Stoeckli M.C., Lanz C., Raddatz G., Vayssier-Taussat M., Birtles R., Schuster S.C., Dehio C. ; "Genomic analysis of Bartonella identifies type IV secretion systems as host adaptability factors."; Nat. Genet. 39:1469-1476(2007).
Web links:	Entrez Genome Project: http://www.ncbi.nlm.nih.gov/sites/entrez?Db=genomeprj&cmd=ShowDetailView&TermToSearch=28109 GIB (DDBJ): http://gib.genes.nig.ac.jp/single/index.php?spid=Btri_CIP105476  EBI Proteome Analysis page

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