| Official Name |
|---|
| CoA-disulfide reductase.
|
| Alternative Name(s) |
|---|
| CoA-disulfide reductase (NAD(P)H). |
| CoADR. |
| Coenzyme A disulfide reductase. |
| NADH:CoA-disulfide oxidoreductase. |
| Reaction catalysed |
|---|
| 2 CoA + NAD(P)(+) <=> CoA-disulfide + NAD(P)H |
| Cofactor(s) |
|---|
| FAD.
|
| Comment(s) |
|---|
- While the enzyme from Staphylococcus aureus has a strong preference
for NADPH, that from the thermophilic archaea Pyrococcus horikoshii
can use both NADH and NADPH efficiently.
- Not identical with EC 1.8.1.6, EC 1.8.1.7, or EC 1.8.1.13.
- Formerly EC 1.6.4.10.
|
| Cross-references |
|---|
| BRENDA | 1.8.1.14 |
| PUMA2 | 1.8.1.14 |
| PRIAM enzyme-specific profiles | 1.8.1.14 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.8.1.14 |
| IUBMB Enzyme Nomenclature | 1.8.1.14 |
| IntEnz | 1.8.1.14 |
| MEDLINE | Find literature relating to 1.8.1.14 |
| MetaCyc | 1.8.1.14 |
| UniProtKB/Swiss-Prot |
| Q9UYU5, CDR_PYRAB; | Q8U1M0, CDR_PYRFU; | O58308, CDR_PYRHO; |
| Q5JGP4, CDR_PYRKO; | A7X0I7, CDR_STAA1; | A6U077, CDR_STAA2; |
| Q2FIA5, CDR_STAA3; | O52582, CDR_STAA8; | A5IRE8, CDR_STAA9; |
| Q2YWW1, CDR_STAAB; | Q5HHB4, CDR_STAAC; | A6QFI1, CDR_STAAE; |
| Q99VC0, CDR_STAAM; | Q7A6H1, CDR_STAAN; | Q6GIB7, CDR_STAAR; |
| Q6GAV6, CDR_STAAS; | A8Z076, CDR_STAAT; | Q8NXE8, CDR_STAAW; |
| Q5HQI9, CDR_STAEQ; | Q8CPT6, CDR_STAES; | Q4L4Y7, CDR_STAHJ; |
| Q49WB0, CDR_STAS1; |
|
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