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NiceZyme View of ENZYME: EC 1.2.1.2

Official Name
Formate dehydrogenase.
Reaction catalysed
Formate + NAD(+) <=> CO(2) + NADH
Cofactor(s)
Flavin; Iron-sulfur; Molybdenum.
Comment(s)
  • The enzyme from most aerobic organisms is devoid of redox-active centers but that from the proteobacterium Methylosinus trichosporium contains iron-sulfur centers, flavin and a molybdenum center.
  • Together with EC 1.12.1.2, forms a system previously known as formate hydrogenlyase.
Cross-references
Biochemical Pathways; map number(s)A7 ; D5 ; G5
PROSITEPDOC00063 ; PDOC00392
BRENDA1.2.1.2
PUMA21.2.1.2
PRIAM enzyme-specific profiles1.2.1.2
KEGG Ligand Database for Enzyme Nomenclature1.2.1.2
IUBMB Enzyme Nomenclature1.2.1.2
IntEnz1.2.1.2
MEDLINEFind literature relating to 1.2.1.2
MetaCyc1.2.1.2
UniProtKB/Swiss-Prot
Q9SXP2, FDH1_ORYSJ;  Q08911, FDH1_YEAST;  Q67U69, FDH2_ORYSJ;  
Q08987, FDH2_YEAST;  Q934F5, FDHA_DESGI;  P06131, FDHA_METFO;  
P61159, FDHA_METJA;  P06130, FDHB_METFO;  Q60316, FDHB_METJA;  
Q50570, FDHB_METTF;  P07658, FDHF_ECOLI;  Q2FEI5, FDHL_STAA3;  
Q2FVV9, FDHL_STAA8;  Q2YYT1, FDHL_STAAB;  Q5HDP9, FDHL_STAAC;  
Q931G2, FDHL_STAAM;  Q99RW4, FDHL_STAAN;  Q6GEC4, FDHL_STAAR;  
Q6G711, FDHL_STAAS;  Q7A057, FDHL_STAAW;  Q4L8G8, FDHL_STAHJ;  
Q49ZN0, FDHL_STAS1;  Q9S7E4, FDH_ARATH;  Q03134, FDH_EMENI;  
Q9ZRI8, FDH_HORVU;  Q07103, FDH_NEUCR;  P33677, FDH_PICAN;  
P33160, FDH_PSESR;  Q07511, FDH_SOLTU;  P24183, FDNG_ECOLI;  
P32176, FDOG_ECOLI;  P46448, FDXG_HAEIN;  

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All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.2.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.2.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-

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