| Official Name |
|---|
| (+)-abscisic acid 8'-hydroxylase.
|
| Alternative Name(s) |
|---|
| (+)-ABA 8'-hydroxylase. |
| ABA 8'-hydroxylase. |
| Reaction catalysed |
|---|
| (+)-abscisate + NADPH + O(2) <=> 8'-hydroxyabscisate + NADP(+) + H(2)O |
| Cofactor(s) |
|---|
| Heme-thiolate.
|
| Comment(s) |
|---|
- Catalyzes the first step in the oxidative degradation of abscisic
acid and is considered to be the pivotal enzyme in controlling the
rate of degradation of this plant hormone.
- CO inhibits the reaction, but its effects can be reversed by the
presence of blue light.
- The 8'-hydroxyabscisate formed can be converted into (-)-phaseic
acid, most probably spontaneously.
- Other enzymes involved in the abscisic-acid biosynthesis pathway are
EC 1.1.1.288, EC 1.2.3.14 and EC 1.13.11.51.
|
| Cross-references |
|---|
| PROSITE | PDOC00081 |
| BRENDA | 1.14.13.93 |
| PUMA2 | 1.14.13.93 |
| PRIAM enzyme-specific profiles | 1.14.13.93 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.14.13.93 |
| IUBMB Enzyme Nomenclature | 1.14.13.93 |
| IntEnz | 1.14.13.93 |
| MEDLINE | Find literature relating to 1.14.13.93 |
| MetaCyc | 1.14.13.93 |
| UniProtKB/Swiss-Prot |
| Q949P1, ABAH1_ARATH; | Q09J79, ABAH1_ORYSI; | Q05JG2, ABAH1_ORYSJ; |
| O81077, ABAH2_ARATH; | Q09J78, ABAH2_ORYSI; | Q6ZDE3, ABAH2_ORYSJ; |
| Q9FH76, ABAH3_ARATH; | A2Z212, ABAH3_ORYSI; | Q0J185, ABAH3_ORYSJ; |
| Q9LJK2, ABAH4_ARATH; |
|
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