ID 1.1.1.3 DE Homoserine dehydrogenase. CA L-homoserine + NAD(P)(+) = L-aspartate 4-semialdehyde + NAD(P)H. CC -!- The enzyme from Saccharomyces cerevisiae acts most rapidly with CC NAD(+); the Neurospora enzyme with NADP(+). CC -!- The enzyme from Escherichia coli is a multifunctional protein, which CC also catalyzes the reaction of EC 2.7.2.4. PR PROSITE; PDOC00800; //